Macrotis lagotis (bilby): 141500287
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Entry
141500287 CDS
T11097
Symbol
PDE4A
Name
(RefSeq) 3',5'-cyclic-AMP phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao00230
Purine metabolism
mlao01100
Metabolic pathways
mlao04024
cAMP signaling pathway
mlao04928
Parathyroid hormone synthesis, secretion and action
mlao05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
141500287 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
141500287 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
141500287 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
141500287 (PDE4A)
Enzymes [BR:
mlao01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
141500287 (PDE4A)
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Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
141500287
NCBI-ProteinID:
XP_074059462
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Position
X:625298017..625332481
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AA seq
831 aa
AA seq
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MELSCSLQAFVLGVPWPLLLRDRRMRRSRSFLAVSVSGDERPRETGESSRCRLSHTGGST
LGTELRSRLHLRRLSSGPYGLGWVDQEPADAAPQPRPNTLALLIPPLISVTRAEPDSFEV
ENGPSPSPGRSPLDSQASPGLVLPPSAPQSQRRESFLYRSDSDYDMSPKTMSRNSSIASE
VHEDLIVTPFAQVLASLRSVRSNFSLLANVPATVGNKKSPVGNQPAVCKATLSEETYQQL
ARETLEELDWCLDQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTT
FLDKQADVEIPAPTPKEQEKQLQQRPQRQPMSQISGVKKLTHSSSLSNSGIPRFGVKTDQ
EELLGKELENLNKWGLNIFQVAEFSNGRSLGCIMYTIFQERDLLKTFKIPVDTLVTYMLT
LEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVS
NQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLNKRQRQSLRRMVIDMV
LATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKPLAL
YRQWTDRIMEEFFHQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLV
HPDAQEILDMLEDNRDWYHSAIPQSPSPPPEEPPGQGQDKFQFELIREEDIAATKPVLQF
EEQDEPAPEMGRVGPGHGPEKGSLPAPPSTRPLSPLVIHHSCQRPDTMEEEEQKPKESTA
AKEAQQPWLVSPQELEADGKVTEVEAASQAEEKTPEEAQALASLEDLECPS
NT seq
2496 nt
NT seq
+upstream
nt +downstream
nt
atggagctttcatgctccctccaggcttttgtcctgggggttccatggcccctacttctt
agggaccgcaggatgaggagaagtcgcagtttcttggccgtgtctgtgagcggagatgag
aggccaagggagaccggggaatctagccgctgtaggctctcccacacagggggcagcact
ctgggcactgagctgcgttcacgtctccaccttcgccgcctttcctccggtccctatggc
ttgggctgggtggaccaggaaccagcggatgcagccccacagccgcggcccaacacgctg
gcgctactgatacctcccctcatctcagtcaccagggcagagcctgacagctttgaggtg
gagaatggaccttctccatccccaggacgtagccccttggattcacaggcgagccccgga
ctggtgctgcctcccagcgccccccagagccagcgccgtgagtctttcctgtaccgatcg
gacagtgactatgacatgtcacccaagaccatgtcccgaaactcttccattgccagtgaa
gtacacgaagacttgattgtgacacccttcgcccaggtgttagcaagtctaagaagtgtc
cgaagcaacttctcccttctggccaatgtaccagccactgttggcaacaagaagtcccca
gtaggcaatcagccagcagtatgcaaggccacactctcagaggagacataccagcaactg
gcccgggagaccctggaagagctagactggtgcttggaccagttagagacaatgcagaca
taccggtcagtgagtgagatggcctcccacaagttcaagaggatgctgaaccgtgagctg
acacacctctcagaaatgagccggtcgggaaatcaggtctcggaatacatctccaccacc
ttcctggacaagcaggctgatgtagagataccagcccctacacccaaggagcaggagaag
caacttcagcaacggccacagaggcaacccatgtcccaaatcagtggggtcaaaaagctc
acacatagttccagtctcagcaactctggcatcccccgatttggggtcaagaccgaccag
gaggagctgttgggcaaggagctggaaaacctgaacaagtggggccttaacatcttccaa
gtagctgagttctccaatggccgatcgctaggatgtatcatgtataccatattccaggag
agagacctgctgaagaccttcaagattccagtggatacattggttacctacatgctgact
ctggaggaccactaccacgctgatgtagcctatcacaacagcctccatgctgctgatgtt
ctacagtccacacacgtgcttttggccacgccagcacttgatgctgtgttcacagacctg
gaaatcctagctgctctgtttgccgcagccatccatgacgttgaccacccgggggtctct
aatcagttcctcatcaataccaactcagaactagccctgatgtacaatgatgagtctgtt
ctggagaatcaccacctggctgtgggcttcaagttgctccaagaagagaattgtgatatc
ttccagaacctgaacaagaggcagaggcagagtcttcgcaggatggtcattgacatggtg
ctggccacagatatgtccaaacatatgagccttctggctgacctgaagaccatggtggaa
accaagaaagtgacaagctcaggggtcctgctgttggacaattatacggaccgaattcag
gtccttcggaacatggtgcactgtgctgacctcagcaacccgacaaagccactggcactg
tacaggcaatggactgaccgcatcatggaagagttcttccaccagggagacaaggagcgg
gaaagaggcatggagattagccctatgtgtgataagcacacagcatctgtggagaaatca
caggtgggctttattgactacattgtgcatccactgtgggagacatgggcagacctggtt
catcctgatgctcaggaaattttggacatgctggaagataatcgggactggtaccatagt
gctatcccacagagcccctcaccaccccctgaagagcctcctggccagggtcaggacaag
ttccaatttgaattaatccgtgaggaggacatagcagccacaaagcctgtcctgcaattt
gaggaacaagatgagccagcccccgagatggggcgggtaggcccaggccatggccccgaa
aagggcagcctacccgccccaccttccacaaggcccctaagcccattagtcattcatcac
agctgtcaaagaccagacacgatggaagaggaagaacagaaaccaaaggagtccacagca
gccaaagaggcgcagcaaccatggctggtatcgcctcaggagctggaggcagacgggaaa
gtaacagaggtcgaagccgcctcacaagcagaggaaaaaacacccgaggaggcccaagcc
ttagccagcctagaggacctggaatgtccatcatga
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