Macrotis lagotis (bilby): 141512365
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Entry
141512365 CDS
T11097
Symbol
PDE4B
Name
(RefSeq) 3',5'-cyclic-AMP phosphodiesterase 4B isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao00230
Purine metabolism
mlao01100
Metabolic pathways
mlao04024
cAMP signaling pathway
mlao04928
Parathyroid hormone synthesis, secretion and action
mlao05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
141512365 (PDE4B)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
141512365 (PDE4B)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
141512365 (PDE4B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
141512365 (PDE4B)
Enzymes [BR:
mlao01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
141512365 (PDE4B)
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Motif
Pfam:
PDEase_I
PDE4_UCR
SPT2_N
Motif
Other DBs
NCBI-GeneID:
141512365
NCBI-ProteinID:
XP_074077344
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Position
2:complement(12169029..12906237)
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AA seq
764 aa
AA seq
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MKKSRSVMTVTADEVPKYMQSNIIQSISGLVDPPVMLNQAHNVKDYLECNLSKSYSSSSN
TLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPDGDSISRPTTLPLLTLPSIAITTVSQE
SFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNS
SLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGATNKRSPAATQPPVSRVNLQDE
SYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSE
YISNTFLDKQNEVEIPSPTQKDREKKKKEQQVMTQISGVKKLMHSSSLNNTSISRFGVKT
EKEDHLAKELEDLNKWGLNIFKVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYM
MTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPG
VSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVID
MVLATDMSKHMGLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSL
ELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWAD
LVQPDAQDILDTLEDNRNWYQSMIPQSPSPPFEDQNRDCQGLMEKFQFELTLEEEDSEGP
EKEGESMGYFGSTKTLCVIDPEHLESPGEAEEETALGDASPVDT
NT seq
2295 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaagcaggagtgttatgacagtgaccgctgatgaggtacccaaatatatgcag
tcaaatattatccagtctatcagtggacttgtggaccctccagtgatgctgaatcaagct
cataatgttaaggattacttggaatgcaacctgagtaaatcttacagctcctccagtaac
accctaggaattgatctctggagggggagaagatgctgctctgggaacctccagttgccc
ccgctatcccagagacagtcagaaagagcccggacacctgatggtgatagcatttcaaga
cctaccactctacctttgctgacacttccaagcattgcaatcacaactgtaagccaagag
agtttcgatgtggaaaatggcccgtctcctggtcgaagccccctggatccacaggccagc
tcttcctcggggctggtgttacacaccacctttccggggcacagccagcggcgagaatca
ttcctctacaggtcagacagtgactatgacctttcaccaaaggctatgtctaggaattct
tcccttccaagtgaacaacatggtgacgacctaatcgtaacaccttttgcacaggtcctc
gccagccttcgaagtgtgagaaataacttcaccctcctgaccaatctgcatggagcaacc
aataagaggtctccagctgctacccaacctcctgtctccagagttaatctccaagacgag
tcctaccagaagctggccatggagaccctggaggagctggactggtgcctggaccagctg
gagaccatccagacctaccgctccgtcagcgagatggcctccaacaagttcaagagaatg
ttgaatcgagaactgacacacctctcggagatgagccggtcagggaaccaggtgtctgaa
tacatttccaacacattcttagataagcagaatgaggtggagattccatctcccactcag
aaagacagggaaaagaagaaaaaagagcagcaagtcatgacccagataagtggagtcaaa
aagctaatgcacagctcaagtctgaacaacaccagtatctctcgctttggagtcaagact
gaaaaggaagatcacctggcaaaagagctggaagacctgaacaaatggggcctcaacatc
ttcaaggtagctggatattctcataacaggcccttgacgtgtatcatgtatgccatattc
caggaaagagaccttttaaagacgttcaaaatttcatctgacacctttgtaacctacatg
atgactttagaagaccattaccattccgacgtggcatatcacaacagcctccatgctgct
gatgttgcccagtcaacccacgttctcctttctactccagccttagatgctgtcttcaca
gatttggaaatcctggctgctatctttgctgctgcgatccatgatgtggatcatccaggg
gtctccaatcaattcctcatcaacacaaattctgaacttgctttgatgtataatgatgag
tctgttttggaaaaccaccacttggctgttgggttcaagttgctccaagaggagcactgt
gacattttccagaatctaaccaagaagcagcgtcagaccctcaggaagatggtgatcgac
atggttttggcaacggatatgtccaagcacatgggcctgttggcagacctgaaaacaatg
gtagagacgaaaaaagtgaccagctctggagtcctccttctggacaactacacagatcgg
atacaggtcctccgcaatatggtacattgtgccgacctgagcaaccccaccaagtctttg
gaattgtaccggcaatggacagaccgtatcatggaggaattcttccaacagggagacaag
gagagagagaggggcatggagattagccccatgtgcgacaaacacactgcctcagtggaa
aaatcccaggttggcttcattgactacattgtccatcccctctgggagacctgggctgac
ctagtccagcccgatgcccaggacatcctggacaccttggaagacaaccggaactggtac
cagagcatgatcccacagagcccctccccacccttcgaggaccagaacagagactgtcaa
ggactgatggagaaattccaatttgaactgaccctggaagaggaggattctgagggtcct
gagaaggagggggagagcatgggctattttggaagcacaaagacactgtgtgtgattgac
ccagagcacctagagtctccgggggaggctgaggaagagactgcgctgggagacgcatcc
cccgtggacacataa
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