Macrotis lagotis (bilby): 141513802
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Entry
141513802 CDS
T11097
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
141513802 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mlao03032
]
141513802 (TOP2A)
03036 Chromosome and associated proteins [BR:
mlao03036
]
141513802 (TOP2A)
Enzymes [BR:
mlao01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
141513802 (TOP2A)
DNA replication proteins [BR:
mlao03032
]
Eukaryotic type
DNA Topoisomerases
141513802 (TOP2A)
Chromosome and associated proteins [BR:
mlao03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
141513802 (TOP2A)
Centrosome formation proteins
Centriole proteins
141513802 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
ComGE
Motif
Other DBs
NCBI-GeneID:
141513802
NCBI-ProteinID:
XP_074080075
LinkDB
All DBs
Position
2:188799528..188823584
Genome browser
AA seq
1554 aa
AA seq
DB search
MEDLSPLQPVNENLQVNKIKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVEVVTQ
QMWVYDEGVGLNYRDVTFVPGLYKIFDEILVNAADNKQRDPKMNCIKVTIDSENNTISIW
NNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTV
ETACKEYKKMFKQTWMDNMGKAGEMTLKSFSGEDYTCITFQPDLSKFKMTNLDKDIVALM
SRRAYDIAGSTKDVKVFLNGNRLPVKGFRSYVDLYVKDKLDETGNPLKIIHEEVNNRWEV
CLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIISRLIDVVKKKNKGGVAVKAHQVKNH
MWIFVNALIENPTFDSQTKENMTLQAKSFGSKCELSEKFIKAAIGCGIVESILNWVKFKA
QIQLNKKCSAVKHNRIKGIPKLDDANDAGSKNSTDCTLILTEGDSAKTLAVSGLGVVGRD
KYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDADSLKSLRYGKIMIM
TDQDQDGSHIKGLLINFIHHNWPSLLRHCFLEEFITPIVKVSRNKQELSFYSLPEFEEWK
NSTENHKKWKVKYYKGLGTSTSKEAKEYFSDMARHRIQFRYSGPEDDAAISLAFSKKQTD
DRKEWLTHFMEDRRQRKLLGLPEDYLYGKATKHLTYNDFINKELILFSNSDNERSIPSMV
DGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSN
NLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAKDDQTLKFLYDDNQRVEPE
WYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTI
DELAPNQYVISGEVSIINSTTIEISELPVRTWTQVYKEQVLEPMLNGTDKTPPLITDYRE
YHTDTTVKFIIKMTEEKLAQAEHAGLHKVFKLQTNLTCNSMVLFDHVGCLKKYDTVLDIL
KDFFDLRLKYYGLRKEWLTGMLGAESAKLNNQARFILEKIEGKIIIENKPKKEIIKVLIQ
RGYDSDPVKAWKEAQQKSPGDNEEENEESENEKEGEKSDSTTDSGPTFNYLLDMPLWYLT
KEKKDELCRQRHEKEQELETLKRKSPSDLWREDLAAFVEELEVVEAKEKRDEQVGVVCKG
KAGAKSKSKKGQLAETLPSPCGRRVVPRVTVEMKAEAEKKIRKKIKTENIEESSQDDSIE
PETLKQRLTKKIKAEPGTKQKKQTKLPFKPIRKENKKNPWSDSESDLSCNESDFYVPPRE
TKLRRTAAAAKTKYTVDLDSDSDISDYKEEFQDEDDDFIPADGSSSHVKSAPKATKGQPT
SKEEEPQKNEVDDLESEEKDMALASSSSSTLDFPDELQIADPGPKKSTAVKKTAAKSQPS
TSTAVTKKRAAPKTSKRVLASKVSTDSISEGPESIVPPKSKKPRIRKPSNSDDSDSDFGK
SISTAKAGKKSKKVDDDFHIDSNSSSAPVVPRARPGRAKKPIKYLEESDEDDIF
NT seq
4665 nt
NT seq
+upstream
nt +downstream
nt
atggaggatctgtcgccgctgcagcctgtaaatgaaaatctacaagtaaataaaataaag
aaaaatgaggacgcaaagaaaagattgtctgttgagagaatctatcaaaagaaaacccag
ttggagcatattttgctccgccctgatacctatattggctctgtggaggttgtgacccag
caaatgtgggtttatgatgaaggagttggacttaactacagagatgtaacttttgttcct
ggtttatacaaaatttttgatgaaattttagtaaatgccgcagacaacaagcaaagggac
ccaaaaatgaattgtattaaagtcacaatagattcggaaaacaatacaattagtatctgg
aataatgggaaaggtattcctgttgtagagcataaagttgagaaggtctatgtacctgct
cttatctttggacagctcttgacttccagtaactatgatgatgatgagaagaaggtcact
ggtggtcgaaatggttatggagccaaattatgcaatatattcagtaccaaatttacggtg
gaaactgcctgtaaagaatataagaaaatgttcaaacagacctggatggataacatggga
aaggcaggggaaatgactctcaagtcctttagtggagaagactacacatgtatcacattt
caacctgatctttctaaatttaaaatgactaatctagacaaggatattgttgccttgatg
tctagaagagcttatgatattgctggttccaccaaagatgtcaaggtctttctcaatgga
aataggctgcctgtaaaaggattccgtagctatgtggatctgtatgtgaaggacaaattg
gatgaaactggcaacccactgaaaattatccatgaagaagtaaacaacaggtgggaagta
tgtttaactatgagtgaaaaaggcttccagcaaattagctttgtcaacagcattgccact
tccaagggtggcagacatgttgattatgtagctgatcaaattataagtagacttattgat
gttgtgaagaaaaagaacaaagggggtgttgcagtaaaagcacatcaggtgaaaaaccac
atgtggatttttgtgaatgccttaattgaaaacccaacctttgactcccaaactaaggaa
aatatgactctgcaggccaagagctttggttcaaaatgtgaattgagtgaaaaattcatc
aaagctgcaattggctgtggaattgtagaaagcatactaaattgggtgaagtttaaggcc
caaatccagttgaataaaaagtgttcagctgttaaacacaatagaatcaagggaattcct
aaacttgatgatgctaatgatgcaggcagtaagaactctacagattgtacacttatcttg
actgagggagactcagccaaaactttagctgtttctggccttggtgtggttgggagagac
aagtatggtgttttcccccttcgaggaaaaatactcaatgttcgagaagcctctcataaa
caaatcatggaaaatgcagaaattaataatatcattaagattgtgggtcttcaatacaag
aaaaactatgaagatgcagattcattgaagagtctccgttatggaaaaataatgattatg
acagatcaggatcaagatggttctcacatcaaaggcttgttgattaatttcatccatcac
aattggccctctcttctgagacattgttttctggaagaatttatcactcccattgtaaag
gtttcaagaaataagcaggaattatcattttatagtcttcctgaatttgaagaatggaaa
aattctactgagaatcataaaaaatggaaagtcaagtactacaaaggtttgggcaccagt
acatcaaaagaagctaaagaatacttttcagatatggccagacatcgaattcaattcaga
tattctggccctgaggatgatgctgcaatcagcctggcctttagcaaaaaacagactgat
gatcgaaaagaatggctaactcatttcatggaagatagaagacagaggaagttacttggc
ctccctgaggattacttatatggaaaagctactaagcatctaacatataatgacttcata
aataaagaactaatcttattttcaaactctgataatgagaggtctatcccatcaatggta
gatggtttaaagccaggtcagagaaaagtcctattcacatgtttcaaaagaaatgacaag
agagaagtgaaggttgcccagttagctggttcagtagcagagatgtcctcttatcatcat
ggtgaaatgtcactcatgatgaccattattaatttggctcaaaattttgtgggcagcaac
aatctcaacctgttgcagcccattggtcagtttggtaccagattgcatggtggcaaagac
tctgctagtcctcgatatatcttcacaatgctcagtccattggctcggttgcttttccca
gcaaaggatgatcagactttgaagttcttatatgatgacaatcaacgtgtagaaccagaa
tggtacattcctattattcccatggtattgataaatggtgcagaagggattggaactggg
tggtcctgtaagatccccaactttgatgtccgagaagttgtgaataatatcagacgtctg
atggatggagaagaacctttaccaatgctacctagttacaaaaatttcaagggtacaatt
gatgagctagctccaaatcaatatgttatcagtggtgaagtatctattataaattcaaca
accattgaaatttctgagcttccagtcagaacttggactcaggtctataaagagcaggtt
ctggaacccatgttgaatggtactgacaagacaccccctctcataacagactacagggaa
taccacactgataccacagtgaagttcattataaagatgactgaagaaaaactggcccaa
gcagagcatgcaggactacacaaagtctttaaacttcagactaatctaacatgtaattcc
atggtgctttttgatcatgttggctgtctaaagaagtatgatactgtactggatatccta
aaagacttctttgatctgagacttaaatattatggactgagaaaagaatggctaactgga
atgcttggtgctgaatctgccaaattgaacaaccaggctcgattcattctagagaagata
gaggggaaaataatcattgaaaataaacctaagaaagagataattaaggttctgatccag
aggggatatgattcagatcctgtcaaagcctggaaggaagctcagcaaaagagtccagga
gacaatgaagaggaaaatgaagaaagtgaaaatgaaaaagaaggtgaaaaaagtgattcc
accactgattctggaccgacttttaattaccttcttgatatgcctctctggtatttgacc
aaagagaagaaagatgaactctgtagacagaggcatgaaaaagagcaagaactagagacc
ttaaaacgaaaaagtccttcagatttatggagagaggacctggctgcttttgttgaagaa
cttgaggttgttgaagccaaggaaaaacgggatgaacaagtgggtgttgtttgtaaaggt
aaagctggtgcaaaatcaaagtcaaagaaaggtcaactggcagaaactttaccttctcct
tgtggtagacgagttgtccctcgagtgactgtagagatgaaagcagaagcagaaaagaaa
atcagaaagaaaattaagactgaaaatatcgaagaaagttctcaagatgacagtatagaa
ccagaaactctgaaacaaagactaaccaaaaagattaaggcagaaccaggtaccaaacaa
aagaagcaaaccaaattgccattcaaaccaatcagaaaagaaaataagaaaaatccttgg
tctgattcagaatctgatttgagttgtaatgaaagtgacttttatgttccccctagagaa
actaaattgcgcaggacagcagcagcagcaaagaccaaatacacagttgatttagattca
gacagcgatatttctgattataaagaggaatttcaagatgaagatgatgattttattcca
gcagatggaagttcatctcatgttaaaagtgcaccaaaagcaactaaaggacaacctact
agcaaagaagaggaaccacagaaaaatgaagttgatgacctagaatctgaggagaaggac
atggctctggcttcttcaagctcttctactttagattttccagatgaacttcagattgca
gatccaggacccaaaaaaagcacagcagtgaaaaagactgcagcaaagagtcagccttcc
acttctacagccgtaacaaagaaaagagcagcaccgaaaacaagcaaaagggttcttgcc
tccaaagtgtctacagactccatctctgaaggccctgaaagtattgtgccacccaaaagc
aagaaacctcgcataaggaagccatctaactctgatgactctgattcagattttggaaaa
agcatatcaacagccaaggcaggaaagaaatccaagaaggtagatgatgatttccatatt
gactcaaattcaagctcagctcctgtggtaccccgggcaagacctggccgagcaaagaag
cctattaaatacctggaagaatcagatgaggatgatatattttaa
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integrated database retrieval system
