Macrotis lagotis (bilby): 141513829
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Entry
141513829 CDS
T11097
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao01521
EGFR tyrosine kinase inhibitor resistance
mlao01522
Endocrine resistance
mlao01524
Platinum drug resistance
mlao04010
MAPK signaling pathway
mlao04012
ErbB signaling pathway
mlao04020
Calcium signaling pathway
mlao04066
HIF-1 signaling pathway
mlao04151
PI3K-Akt signaling pathway
mlao04510
Focal adhesion
mlao04520
Adherens junction
mlao04530
Tight junction
mlao05200
Pathways in cancer
mlao05205
Proteoglycans in cancer
mlao05206
MicroRNAs in cancer
mlao05212
Pancreatic cancer
mlao05213
Endometrial cancer
mlao05215
Prostate cancer
mlao05219
Bladder cancer
mlao05223
Non-small cell lung cancer
mlao05224
Breast cancer
mlao05226
Gastric cancer
mlao05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
141513829 (ERBB2)
04012 ErbB signaling pathway
141513829 (ERBB2)
04066 HIF-1 signaling pathway
141513829 (ERBB2)
04020 Calcium signaling pathway
141513829 (ERBB2)
04151 PI3K-Akt signaling pathway
141513829 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
141513829 (ERBB2)
04520 Adherens junction
141513829 (ERBB2)
04530 Tight junction
141513829 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
141513829 (ERBB2)
05206 MicroRNAs in cancer
141513829 (ERBB2)
05205 Proteoglycans in cancer
141513829 (ERBB2)
05230 Central carbon metabolism in cancer
141513829 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
141513829 (ERBB2)
05226 Gastric cancer
141513829 (ERBB2)
05219 Bladder cancer
141513829 (ERBB2)
05215 Prostate cancer
141513829 (ERBB2)
05213 Endometrial cancer
141513829 (ERBB2)
05224 Breast cancer
141513829 (ERBB2)
05223 Non-small cell lung cancer
141513829 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
141513829 (ERBB2)
01524 Platinum drug resistance
141513829 (ERBB2)
01522 Endocrine resistance
141513829 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlao01001
]
141513829 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mlao04147
]
141513829 (ERBB2)
04090 CD molecules [BR:
mlao04090
]
141513829 (ERBB2)
Enzymes [BR:
mlao01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
141513829 (ERBB2)
Protein kinases [BR:
mlao01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
141513829 (ERBB2)
Exosome [BR:
mlao04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
141513829 (ERBB2)
CD molecules [BR:
mlao04090
]
Proteins
141513829 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
ABC1
PDGLE
Motif
Other DBs
NCBI-GeneID:
141513829
NCBI-ProteinID:
XP_074080127
LinkDB
All DBs
Position
2:complement(189559196..189588738)
Genome browser
AA seq
1255 aa
AA seq
DB search
MDLSGCCCWGLLLVLLPPAVWGTQVCTGTDMKLQYPASIENHLDTLSHLYQGCQVVQGNL
ELTYLPADANLSFLQDIQEVQGYVLIAHSLVKSFPLQRLRIIRGTQLFEDKYALVVLDNG
IPLGTAPPTPEGPSGLRELPLRSLTEILKGGVQIQNNPQLCHQDTVLWTDIFHKNNYLGT
TSIDRNHSRTCSPCSSACKSGWCWGEGPDNCQSLTSTICASGCARCKGPLPTDCCHEQCA
AGCTGPKHSDCLACLHFNHSGICEQHCPPLVIYNSDTFESMPNPDGRYTFGSSCVKSCPY
NYLATDVGSTSCTLVCPLHSQEVTAEDGTHRCEKCSKACPKVCYGLGMGHLRSVRAVNST
NIQDFAGCKKIFGSLAFLPETFAGDMATNTSPLMPEDLKVFENLEEITGYLYISAWPDSL
SDLSIFQNLRVIRGRVLHNGVYSLTLEHLGIGWLGLRSLRELGSGLALIHHNDHLCFVHT
VPWNQLFRNPRQALLYSANRPSQECAREGLACYSLCAQGHCWGPGPTQCLNCSQFLRGQE
CVEECRVMQGYPREYVKDRRCFPCHGECQPQNGTETCFGSEADKCVACAHFKDSLACVAQ
CPSGVKPDLSFIPIWKYPDDEGICQTCPTNCTHSCTVLDDKGCPAEQKPSPVTSIIAAVV
GVLLALIIGLLIGILIKRRKQQERKHTMRRLLQETELVEPLTPSGALPNQAQMRILKETE
LRKVKVLGSGAFGTVYKGIWIPDGESVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGS
PYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLCSQDLLNWCVQIAKGMNYLEEV
RLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILCRRF
THQSDVWSYGVTVWELMTFGAKPYEGIPAREIPDLLEKGDRLPQPPVCTIDVYMIMVKCW
MIDSECRPRFRELVTEFSRMARDPQRFVVIQNEDSGPASPLDSTFYRSLLEEDDMGDLVD
AEEYLVPQQGFFCPDPPLAPGPGGTTHRRHRSSSTRSGGELPGVLEGSEEDPPQSPAEPW
EGTGSDVFDGEPGGSLKGLQGIPPRDLSPLQRYSEDPTRPLSPEMDGYVVPPTCGPQPEY
VNQPEVHLPPPSPLEGTLTPPHPSSSTLEHPKLPPPGKNGVVKDIFTFGAAVENPEYLAP
HGGGPHHLSPTAFSPAFDNLYYWDQDPSDRGAAPNGFAGTPTAENPEYLGLDMTV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggacctgtccggctgctgctgttgggggcttcttctggtcctcctgcccccagcagtc
tggggaacccaagtgtgcacaggcacagacatgaagttgcagtatcctgccagtattgag
aatcaccttgatacattgagccacctgtaccaaggatgccaggttgtacaaggcaacctg
gagctcacttacttacctgctgatgccaacctctccttcctccaggacatccaagaagta
cagggctatgtgctgatagcccacagccttgtgaagagtttcccactgcagaggctccgc
atcatccgaggcacccagctctttgaggacaaatatgccttggtcgttctggacaatggg
attccccttgggactgctcctcccacacccgagggcccctctggtctccgggagctgcca
cttcgaagcctcacagagattctgaaaggtggggtacagatccagaacaacccccagctg
tgtcaccaggacacagtgctgtggactgacatcttccataagaacaactacttgggcacc
acctccatcgatagaaatcacagccgaacttgcagcccttgttcttcagcatgtaaatct
ggctggtgctggggggaaggacctgacaactgtcagagcttgaccagcacaatctgtgcc
agtggctgtgcccgttgcaaggggcccctccccacagactgctgccatgagcaatgtgct
gctggctgcactggccccaagcattctgactgcctggcctgcctccacttcaaccacagt
ggcatctgtgagcagcattgcccaccgctggtcatctacaactcagacacctttgagtca
atgcctaatcctgatgggcgatacacctttgggtccagttgtgtgaaatcatgtccctat
aattacttggctacagatgtgggctccacatcctgcacccttgtgtgtcccctacacagt
caagaggtgactgctgaggatggaacccatcggtgtgagaaatgcagcaaggcctgcccc
aaagtgtgttatggcctgggcatggggcacttgcggtcagtgagagctgtcaacagtacc
aacatccaggactttgctggttgcaagaagatctttggaagtctggctttcctgcctgag
acctttgcaggggacatggccaccaatacttcaccactaatgcctgaagacctcaaggtc
tttgagaacctggaggagattacaggttacctgtacatctcagcctggcctgacagtctc
tctgacctcagcatctttcaaaatctaagggtgatcaggggaagggtgttgcacaatggt
gtctactccctgactctggagcatctgggtattggctggctagggctgcggtcactgaga
gagctgggcagtgggttggcactcatccatcacaatgaccacctatgctttgtccacacg
gtgccttggaaccaactcttccgtaacccccgccaggccctgctctacagtgccaaccga
ccttcccaggagtgtgcaagggagggactagcatgctactccctgtgtgctcaggggcac
tgctggggccctggaccaacccagtgtctcaactgcagccaatttctgcgaggacaggag
tgtgtggaggagtgccgggtcatgcaggggtacccccgagaatatgtcaaggacaggcgc
tgcttcccatgccatggggagtgccagccccaaaatggtactgagacctgctttggatcg
gaggctgacaaatgtgtagcctgtgcacacttcaaggactctcttgcctgtgtggcccaa
tgccccagtggggtgaagccagatctttccttcatacctatctggaagtacccagatgat
gaaggcatttgccagacttgccctaccaactgtacccactcctgtactgtactggatgac
aaaggctgtcctgctgaacagaaacccagccctgtgacctccatcattgcagcagtggtt
ggggtgctcctagctctcatcataggcctgctcattggcatcttgattaagcgtcggaaa
cagcaggaacgaaagcacaccatgagaaggctgctacaggagaccgagctggtggaaccc
ttgacgcctagtggagcattgcccaaccaagctcagatgcgtatcctaaaagagaccgag
ctgaggaaagtgaaggttcttggttctggagcttttggcactgtctacaagggtatttgg
atccctgatggtgaaagtgtgaagattccagtggctatcaaggtgttgagggaaaacaca
tcccccaaagccaacaaggagatcttggatgaagcgtacgtgatggcaggtgttggttct
ccatatgtttctcgacttctgggcatctgcttgacatccacggtgcagctggtgacccag
cttatgccctatggctgccttctggaccatgtgcgtgaaaaccgagggcggctctgctcc
caggacctcctcaactggtgtgtgcagattgccaaggggatgaactatctggaggaggtt
cggctagtacatagagacctggctgccaggaatgtgctagtcaaaagtcccaaccacgtc
aagatcactgactttggactcgcaagactcttggacattgatgagacggagtaccatgca
gatgggggcaaggttcccatcaagtggatggcactagaatccattctctgccgaagattc
acccatcagagtgatgtgtggagctatggggtgacagtgtgggaactgatgacctttggg
gctaagccatatgaggggattcctgcccgagagattcctgacctgttggagaagggtgac
cggctaccacagcccccagtctgcaccattgatgtctacatgatcatggtcaaatgttgg
atgattgactctgagtgtcggcctcggttccgggagcttgttactgaattctcacgaatg
gcccgagaccctcaacgctttgttgtcattcagaacgaggattctggtccagccagtccc
ctggacagcactttctaccgttctttgttggaagaagatgacatgggtgacttggtggat
gcagaagaatacctggtgccccagcaaggtttcttctgccctgaccctcccttggctcca
ggtcccgggggtactacccaccggagacacagaagttcttctacaaggagtggtggggag
cttccaggagtactggaaggctcagaagaggaccctccccaatctccagcagagccctgg
gaagggactggttcagatgtgtttgatggggagcctggcgggagccttaaggggctccag
ggaatccctcctcgagacctcagccccctgcagcgctacagtgaggatcccacacgacca
ctatcccctgagatggatggctacgttgtcccacctacctgtggtccccagcctgaatat
gtgaaccagccagaggtgcacctaccacccccttcacccctggaagggaccctgacacca
cctcacccatccagctccactctggaacatcccaagttgcctcctccagggaagaatgga
gtggtgaaagacatatttacctttggtgcagctgtggagaaccccgagtacttggccccc
catggagggggaccccatcatctttccccaactgccttcagcccagcctttgacaacctc
tattactgggaccaggatccttctgatcgaggggcagctcctaatggctttgcagggacc
cccacagctgagaaccctgagtacttgggtttggatatgactgtgtga
DBGET
integrated database retrieval system