KEGG   Macrotis lagotis (bilby): 141514321
Entry
141514321         CDS       T11097                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
mlao  Macrotis lagotis (bilby)
Pathway
mlao04120  Ubiquitin mediated proteolysis
mlao04380  Osteoclast differentiation
mlao04630  JAK-STAT signaling pathway
mlao04668  TNF signaling pathway
mlao04910  Insulin signaling pathway
mlao04917  Prolactin signaling pathway
mlao04920  Adipocytokine signaling pathway
mlao04930  Type II diabetes mellitus
mlao04931  Insulin resistance
mlao04932  Non-alcoholic fatty liver disease
mlao04935  Growth hormone synthesis, secretion and action
mlao05160  Hepatitis C
mlao05164  Influenza A
mlao05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:mlao00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    141514321 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    141514321 (SOCS3)
   04668 TNF signaling pathway
    141514321 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    141514321 (SOCS3)
   04920 Adipocytokine signaling pathway
    141514321 (SOCS3)
   04917 Prolactin signaling pathway
    141514321 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    141514321 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    141514321 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    141514321 (SOCS3)
   05164 Influenza A
    141514321 (SOCS3)
   05168 Herpes simplex virus 1 infection
    141514321 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    141514321 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    141514321 (SOCS3)
   04931 Insulin resistance
    141514321 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:mlao04121]
    141514321 (SOCS3)
Ubiquitin system [BR:mlao04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     141514321 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 141514321
NCBI-ProteinID: XP_074081143
LinkDB
Position
2:227511847..227516014
AA seq 226 aa
MVTHSKFPATGMNRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPNSSCPSSASSAASPSSSLQDQMLPQPLSGAPPKRTYYIYSGGEKIPLVLS
RPLSSNVASLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 681 nt   +upstreamnt  +downstreamnt
atggtaacccacagcaagttccccgccaccgggatgaaccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgctgtccgcaag
ttgcaagagagcggcttttactggagtgcggtgaccggtggagaggccaacctgctgcta
agcgcggagcctgcgggcaccttcctcatccgagacagctcggatcagcgccacttcttc
accctcagcgtcaaaacccagtcagggacaaagaacctgcggatccagtgcgagggcggg
agtttctccctgcaaagcgatccgcggagcactcagccggtgccccgctttgactgtgta
ctcaaactggtacatcactacatgccccccaactcttcttgcccctcctctgcttcctcc
gcggcctccccctcctcctccttgcaggatcagatgctccctcaacctctctctggggca
cctcctaagcgaacctattacatttactctgggggagagaagatccccttggtgctcagt
cgacccctttcctccaacgtggccagcctgcagcacctctgtcggaagaccgttaatgga
cacctggactcctatgagaaagtcacccaactccctgggcccatcagggagttcctggac
cagtacgatgcccctctttaa

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