KEGG   Macrotis lagotis (bilby): 141515428
Entry
141515428         CDS       T11097                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
mlao  Macrotis lagotis (bilby)
Pathway
mlao04010  MAPK signaling pathway
mlao04022  cGMP-PKG signaling pathway
mlao04137  Mitophagy - animal
mlao04141  Protein processing in endoplasmic reticulum
mlao04151  PI3K-Akt signaling pathway
mlao04210  Apoptosis
mlao04211  Longevity regulating pathway
mlao04261  Adrenergic signaling in cardiomyocytes
mlao04668  TNF signaling pathway
mlao04720  Long-term potentiation
mlao04722  Neurotrophin signaling pathway
mlao04725  Cholinergic synapse
mlao04728  Dopaminergic synapse
mlao04911  Insulin secretion
mlao04912  GnRH signaling pathway
mlao04915  Estrogen signaling pathway
mlao04918  Thyroid hormone synthesis
mlao04922  Glucagon signaling pathway
mlao04925  Aldosterone synthesis and secretion
mlao04926  Relaxin signaling pathway
mlao04927  Cortisol synthesis and secretion
mlao04928  Parathyroid hormone synthesis, secretion and action
mlao04932  Non-alcoholic fatty liver disease
mlao04934  Cushing syndrome
mlao04935  Growth hormone synthesis, secretion and action
mlao05010  Alzheimer disease
mlao05012  Parkinson disease
mlao05014  Amyotrophic lateral sclerosis
mlao05020  Prion disease
mlao05022  Pathways of neurodegeneration - multiple diseases
mlao05030  Cocaine addiction
mlao05031  Amphetamine addiction
mlao05034  Alcoholism
mlao05161  Hepatitis B
mlao05163  Human cytomegalovirus infection
mlao05166  Human T-cell leukemia virus 1 infection
mlao05203  Viral carcinogenesis
mlao05207  Chemical carcinogenesis - receptor activation
mlao05215  Prostate cancer
mlao05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlao00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    141515428 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    141515428 (ATF4)
   04668 TNF signaling pathway
    141515428 (ATF4)
   04022 cGMP-PKG signaling pathway
    141515428 (ATF4)
   04151 PI3K-Akt signaling pathway
    141515428 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    141515428 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    141515428 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    141515428 (ATF4)
   04922 Glucagon signaling pathway
    141515428 (ATF4)
   04912 GnRH signaling pathway
    141515428 (ATF4)
   04915 Estrogen signaling pathway
    141515428 (ATF4)
   04926 Relaxin signaling pathway
    141515428 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    141515428 (ATF4)
   04918 Thyroid hormone synthesis
    141515428 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    141515428 (ATF4)
   04925 Aldosterone synthesis and secretion
    141515428 (ATF4)
   04927 Cortisol synthesis and secretion
    141515428 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    141515428 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    141515428 (ATF4)
   04728 Dopaminergic synapse
    141515428 (ATF4)
   04720 Long-term potentiation
    141515428 (ATF4)
   04722 Neurotrophin signaling pathway
    141515428 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    141515428 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    141515428 (ATF4)
   05203 Viral carcinogenesis
    141515428 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    141515428 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    141515428 (ATF4)
   05161 Hepatitis B
    141515428 (ATF4)
   05163 Human cytomegalovirus infection
    141515428 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    141515428 (ATF4)
   05012 Parkinson disease
    141515428 (ATF4)
   05014 Amyotrophic lateral sclerosis
    141515428 (ATF4)
   05020 Prion disease
    141515428 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    141515428 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    141515428 (ATF4)
   05031 Amphetamine addiction
    141515428 (ATF4)
   05034 Alcoholism
    141515428 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    141515428 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    141515428 (ATF4)
   04934 Cushing syndrome
    141515428 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mlao03000]
    141515428 (ATF4)
Transcription factors [BR:mlao03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    141515428 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 LepB_GAP_N Asd-4 Laminin_II AAA_13 ZapB
Other DBs
NCBI-GeneID: 141515428
NCBI-ProteinID: XP_074083074
LinkDB
Position
2:331934833..331936586
AA seq 346 aa
MTEMSFLSSDLLWGDLLSPFNQSGLGAEESLGPLDDYLEEAKPLKSHGLSGDKAKAVSSD
WQAVEGIFTATDYGKEDAFSGMDWMVEKMDLKEFDFDALLGMDDLESTCSELIATLEDSC
DLFDPLATNDQEPPTTVNSIGQFPETLLEPDHVSPSTSHQSFPLSLRALTSTPDHTFSLE
LGSEVDVLEGDRKPDTVYDLIPKGIKEEEAPSDSDSGIGVCTSPESYLGSPQHSPSTSTA
SLNESRLSAEAVFLSARPKPYDRPLEDKKEKKIDKKLKKMEQNKTAATRYRQKKRAEQEA
LSGECRELEQRNEALKEKADALSKEIQYLKDLIEEVRKAKEKRKSS
NT seq 1041 nt   +upstreamnt  +downstreamnt
atgacggagatgagcttcctgagcagcgacttgttgtggggggacttgctgtcccccttc
aaccagtcgggtttgggggctgaggaaagcctgggccccctagatgactacctggaggag
gccaagcccctcaaatcgcatgggctctccggcgacaaggctaaggcagtctcttccgat
tggcaggctgtggagggtattttcactgccacagactatggcaaggaggatgccttctcg
ggcatggattggatggtggagaaaatggatctgaaggagtttgatttcgatgcccttttg
ggtatggacgacctggaatccacctgctccgagcttattgccacgttggaagactcgtgt
gatctgtttgatcccttggccaccaatgatcaagagccccccacaacagttaattcaatt
ggccagttccccgaaactctccttgagcccgatcacgtcagccccagtacctcccatcag
tcttttcccctttctctaagggccctgacctccacaccagaccatacttttagtttagag
ctaggtagcgaagtggatgtcttagaaggagacagaaaaccagatactgtgtatgacttg
ataccaaaaggcatcaaagaggaagaagccccctcagatagcgacagtgggattggcgtc
tgtacgagccccgagtcttacctgggctcgcctcagcacagcccctccacttccacggct
tctctgaatgagagccgactctccgcagaagccgtgtttctctctgcccgccccaaacct
tacgaccgtccccttgaggacaagaaagagaaaaagattgacaaaaaactcaaaaaaatg
gaacagaacaagactgccgccactcgttacaggcagaaaaagcgggcagagcaggaggcg
ctatctggggagtgcagagagctagagcagaggaatgaggctttgaaggagaaagcagat
gccctgagcaaggagatccagtatttgaaggacttgatagaagaggtccgcaaggccaag
gagaagaggaaaagttcctaa

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