KEGG   Macrotis lagotis (bilby): 141515527
Entry
141515527         CDS       T11097                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mlao  Macrotis lagotis (bilby)
Pathway
mlao01522  Endocrine resistance
mlao04010  MAPK signaling pathway
mlao04015  Rap1 signaling pathway
mlao04068  FoxO signaling pathway
mlao04071  Sphingolipid signaling pathway
mlao04114  Oocyte meiosis
mlao04148  Efferocytosis
mlao04218  Cellular senescence
mlao04261  Adrenergic signaling in cardiomyocytes
mlao04370  VEGF signaling pathway
mlao04380  Osteoclast differentiation
mlao04517  IgSF CAM signaling
mlao04550  Signaling pathways regulating pluripotency of stem cells
mlao04611  Platelet activation
mlao04613  Neutrophil extracellular trap formation
mlao04620  Toll-like receptor signaling pathway
mlao04621  NOD-like receptor signaling pathway
mlao04622  RIG-I-like receptor signaling pathway
mlao04625  C-type lectin receptor signaling pathway
mlao04657  IL-17 signaling pathway
mlao04658  Th1 and Th2 cell differentiation
mlao04659  Th17 cell differentiation
mlao04660  T cell receptor signaling pathway
mlao04664  Fc epsilon RI signaling pathway
mlao04668  TNF signaling pathway
mlao04670  Leukocyte transendothelial migration
mlao04714  Thermogenesis
mlao04722  Neurotrophin signaling pathway
mlao04723  Retrograde endocannabinoid signaling
mlao04728  Dopaminergic synapse
mlao04750  Inflammatory mediator regulation of TRP channels
mlao04912  GnRH signaling pathway
mlao04914  Progesterone-mediated oocyte maturation
mlao04917  Prolactin signaling pathway
mlao04926  Relaxin signaling pathway
mlao04932  Non-alcoholic fatty liver disease
mlao04933  AGE-RAGE signaling pathway in diabetic complications
mlao04935  Growth hormone synthesis, secretion and action
mlao04936  Alcoholic liver disease
mlao05014  Amyotrophic lateral sclerosis
mlao05020  Prion disease
mlao05022  Pathways of neurodegeneration - multiple diseases
mlao05132  Salmonella infection
mlao05133  Pertussis
mlao05135  Yersinia infection
mlao05140  Leishmaniasis
mlao05142  Chagas disease
mlao05145  Toxoplasmosis
mlao05152  Tuberculosis
mlao05161  Hepatitis B
mlao05163  Human cytomegalovirus infection
mlao05167  Kaposi sarcoma-associated herpesvirus infection
mlao05169  Epstein-Barr virus infection
mlao05170  Human immunodeficiency virus 1 infection
mlao05171  Coronavirus disease - COVID-19
mlao05205  Proteoglycans in cancer
mlao05208  Chemical carcinogenesis - reactive oxygen species
mlao05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mlao05415  Diabetic cardiomyopathy
mlao05417  Lipid and atherosclerosis
mlao05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlao00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    141515527 (MAPK12)
   04015 Rap1 signaling pathway
    141515527 (MAPK12)
   04370 VEGF signaling pathway
    141515527 (MAPK12)
   04668 TNF signaling pathway
    141515527 (MAPK12)
   04068 FoxO signaling pathway
    141515527 (MAPK12)
   04071 Sphingolipid signaling pathway
    141515527 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    141515527 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    141515527 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    141515527 (MAPK12)
   04218 Cellular senescence
    141515527 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    141515527 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    141515527 (MAPK12)
   04613 Neutrophil extracellular trap formation
    141515527 (MAPK12)
   04620 Toll-like receptor signaling pathway
    141515527 (MAPK12)
   04621 NOD-like receptor signaling pathway
    141515527 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    141515527 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    141515527 (MAPK12)
   04660 T cell receptor signaling pathway
    141515527 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    141515527 (MAPK12)
   04659 Th17 cell differentiation
    141515527 (MAPK12)
   04657 IL-17 signaling pathway
    141515527 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    141515527 (MAPK12)
   04670 Leukocyte transendothelial migration
    141515527 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    141515527 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    141515527 (MAPK12)
   04917 Prolactin signaling pathway
    141515527 (MAPK12)
   04926 Relaxin signaling pathway
    141515527 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    141515527 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    141515527 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    141515527 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    141515527 (MAPK12)
   04722 Neurotrophin signaling pathway
    141515527 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    141515527 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    141515527 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    141515527 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    141515527 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    141515527 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    141515527 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    141515527 (MAPK12)
   05161 Hepatitis B
    141515527 (MAPK12)
   05171 Coronavirus disease - COVID-19
    141515527 (MAPK12)
   05163 Human cytomegalovirus infection
    141515527 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    141515527 (MAPK12)
   05169 Epstein-Barr virus infection
    141515527 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    141515527 (MAPK12)
   05135 Yersinia infection
    141515527 (MAPK12)
   05133 Pertussis
    141515527 (MAPK12)
   05152 Tuberculosis
    141515527 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    141515527 (MAPK12)
   05140 Leishmaniasis
    141515527 (MAPK12)
   05142 Chagas disease
    141515527 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    141515527 (MAPK12)
   05020 Prion disease
    141515527 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    141515527 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    141515527 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    141515527 (MAPK12)
   05415 Diabetic cardiomyopathy
    141515527 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    141515527 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    141515527 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    141515527 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    141515527 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlao01001]
    141515527 (MAPK12)
Enzymes [BR:mlao01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     141515527 (MAPK12)
Protein kinases [BR:mlao01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   141515527 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH RIO1 Kdo Kinase-like Haspin_kinase FTA2
Other DBs
NCBI-GeneID: 141515527
NCBI-ProteinID: XP_074083300
LinkDB
Position
2:337225687..337244324
AA seq 364 aa
MSSPPPPRKGFYRQEVTKTAWEVRELYRDLEPVGSGAYGAVCSATDSRTGTKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDDTLDDFTDFYLVMPFMGTDLSKLM
KHEKLSDDRIQFLVYQILRGLKYIHAAGIVHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKILFKGSDHLDQLMEIMK
VTGTPPPEFVQRLKSQDAKKYMESLPELEKKDFASVLKNATPLAVNLLEKMLVLDAEKRV
TAAEALTHPYFETVHESEDEPQAQLYDDSFDDVDRTLDEWKRVTYKEVLNFKPPRLLGSK
ETSL
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgagctccccgccgcccccccggaaaggcttttaccggcaggaggtcactaagacggcg
tgggaggtgcgggaactctaccgggacctggagccggtgggctcgggggcgtacggggcc
gtgtgctctgccactgacagccggacgggcaccaaggtggccatcaagaagctctaccgc
cccttccagtcggagctgttcgccaagcgggcgtaccgggagctgcggctgctcaaacac
atgaggcacgagaacgtgatcggcttactggacgtcttcaccccagatgacacactggat
gacttcacggacttctacttggtcatgcctttcatgggcacggaccttagcaagctgatg
aagcatgaaaagctcagcgatgaccggatccaattcttggtctaccagatccttcgaggc
ctcaagtacatccatgctgctggcatcgtccacagggatcttaaacctggaaacctggct
gtgaatgaagactgtgagctgaagattctggactttggcctggccagacaagcagatagt
gagatgaccggttatgtggtgaccaggtggtaccgagcccccgaagtgatccttaactgg
atgcattacacacaaacagtggatatctggtccgtcggctgcatcatggcagagatgatc
accgggaagatccttttcaaagggagtgatcacctcgaccagctgatggagatcatgaag
gtgactgggacacctcctccagagtttgtgcagcggttgaagagtcaggatgccaagaaa
tacatggagagtctcccagagctggagaagaaggactttgcttccgtcctgaagaatgcc
acccccttggctgtgaacctgctagagaagatgttggtgctggatgctgagaagcgagtg
acggccgcagaggccttgactcacccctactttgagactgtgcatgagtctgaggatgag
ccccaggcccagctgtatgacgactcctttgatgatgtcgaccgaaccctggatgagtgg
aaacgagtcacatacaaagaagttctcaactttaagccccctcggctcctgggttcaaag
gagacatctctgtga

DBGET integrated database retrieval system