Macrotis lagotis (bilby): 141517927
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Entry
141517927 CDS
T11097
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao01521
EGFR tyrosine kinase inhibitor resistance
mlao04010
MAPK signaling pathway
mlao04014
Ras signaling pathway
mlao04015
Rap1 signaling pathway
mlao04020
Calcium signaling pathway
mlao04072
Phospholipase D signaling pathway
mlao04144
Endocytosis
mlao04151
PI3K-Akt signaling pathway
mlao04510
Focal adhesion
mlao04540
Gap junction
mlao04630
JAK-STAT signaling pathway
mlao04810
Regulation of actin cytoskeleton
mlao05163
Human cytomegalovirus infection
mlao05200
Pathways in cancer
mlao05206
MicroRNAs in cancer
mlao05214
Glioma
mlao05215
Prostate cancer
mlao05218
Melanoma
mlao05230
Central carbon metabolism in cancer
mlao05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
141517927 (PDGFRA)
04014 Ras signaling pathway
141517927 (PDGFRA)
04015 Rap1 signaling pathway
141517927 (PDGFRA)
04630 JAK-STAT signaling pathway
141517927 (PDGFRA)
04020 Calcium signaling pathway
141517927 (PDGFRA)
04072 Phospholipase D signaling pathway
141517927 (PDGFRA)
04151 PI3K-Akt signaling pathway
141517927 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
141517927 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
141517927 (PDGFRA)
04540 Gap junction
141517927 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
141517927 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
141517927 (PDGFRA)
05206 MicroRNAs in cancer
141517927 (PDGFRA)
05230 Central carbon metabolism in cancer
141517927 (PDGFRA)
05231 Choline metabolism in cancer
141517927 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
141517927 (PDGFRA)
05218 Melanoma
141517927 (PDGFRA)
05215 Prostate cancer
141517927 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
141517927 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
141517927 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlao01001
]
141517927 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mlao04090
]
141517927 (PDGFRA)
Enzymes [BR:
mlao01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
141517927 (PDGFRA)
Protein kinases [BR:
mlao01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
141517927 (PDGFRA)
CD molecules [BR:
mlao04090
]
Proteins
141517927 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_PDGFR_d4
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
VEGFR-1-like_Ig-like
V-set
Motif
Other DBs
NCBI-GeneID:
141517927
NCBI-ProteinID:
XP_074085516
LinkDB
All DBs
Position
3:complement(163601846..163648073)
Genome browser
AA seq
1086 aa
AA seq
DB search
MGASPWVFLVLGYLLTGPWLTFCQLPLPTVFPNEDEKVVQLHSSFTLRCSGDSEVSWQYP
MQDEEDQKIEVRNEENNSGLFVTVLEVVNASAVHTGQYTCYYNHTQTEETEIEGRDIYIY
VPDPDIAFVPSVMVDHLIFVEEHDSVTIPCRTTDPQAQVTLLNSDDKVVHAFYDSRQGFV
GNFAMGQFKCETIIKGKKFQTIPFNIYTITATPELEVEIEAAKTVYKTGETLVVTCAVLH
NEVVDLQWNYPGKVKNKGILKVDEIKVPSLKLVYTLTVPKVTVKDSGDYECAARHATKET
KEIKKVTISVHEKGFIELKPNFSQMETINLHEVRHFVVDVQAYPPPKISWLKDNMTVIEN
LTEIITGLDKIQEIRYQSKLKLIRAKEEDSGYYTILAQNEDDIKNYTFELTIQVPASILD
LEDDNHNSAGGQTVKCTAEGTPLPVVEWMICKDITKCNNETSWTALASNMSDITTQKHES
STVKSQVTFNKIEDTMSVRCLAKNSLGAVSRELKLVAPAMRSELTVAASVLVLLVIVIFS
LIILIIIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGS
GAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLL
GACTKSGPIYIITEYCFYGDLVNYLHKNRDNFLSHNPEKTKKELDIFGMNSADESTRSYV
ILSFENNGDYMDMKQADTTQYVPMLERKQGSKYSDIQRSMYDRPASYKKKSESDPEVKNL
LSDDSSEGLSLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLAR
DIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMV
DSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKKS
YEKIHLDFLKSDHPAVARMRVECDNAYIGVTYKNEDKLKDWEGNYDEQRLSADSGYIIPL
PDIDPIPEDDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDL
VEDSFL
NT seq
3261 nt
NT seq
+upstream
nt +downstream
nt
atgggtgcctccccatgggtgttcctggtcttgggatatctcctcacagggccgtggctc
acattttgccagcttccattacccactgtctttccgaatgaggatgaaaaggttgtgcag
ctgcattcatcttttaccctaagatgctctggggacagtgaagtgagctggcaatacccc
atgcaggatgaagaggaccaaaaaatagaagtcagaaatgaggagaacaacagtggcctt
tttgtgacggtcctggaagtggtcaatgcctcagctgtacacacagggcagtatacttgt
tattacaatcatactcagacagaggagactgaaatcgaaggccgagatatctatatttat
gtgccagatccagacattgcctttgtaccttcagtcatggttgatcatttaatttttgtg
gaagaacatgattctgtcaccattccatgtcgcacaactgaccctcaggctcaagtaacc
ctgctcaacagtgatgacaaagtggtacatgcattctatgacagcagacagggctttgtt
ggaaactttgccatgggacaattcaagtgtgagacaatcatcaaagggaaaaagttccaa
acgattccattcaacatttataccataacagctactccagagcttgaagttgagatagaa
gcagcgaaaactgtttataaaacaggagaaactcttgttgtaacttgtgctgtcttgcac
aatgaggtggttgaccttcagtggaattaccctggaaaagtgaaaaacaaaggcatttta
aaagttgatgaaatcaaagttccatctcttaagttggtgtacacgctgactgtccctaag
gtgacagtgaaagacagtggagactatgaatgtgctgcccgtcatgctaccaaggaaact
aaggaaattaagaaagtcaccatttctgttcatgagaaaggatttattgaactcaaaccc
aacttcagccagatggaaaccattaacttacatgaagtccgccattttgtagtggatgtg
caagcatatccaccgccaaagatatcctggcttaaggacaatatgactgtgattgagaat
ctgactgaaatcatcactggcttagataagatccaggaaataagatatcaaagcaagtta
aaactgattcgtgctaaggaagaagacagtggatattatactattttggctcaaaatgag
gatgatattaagaactatacttttgaacttacaattcaagttccagcttctattctggac
ctggaggatgacaaccacaactctgcaggtggacagacggtcaaatgcacagcagaaggg
acaccacttccagtcgtggaatggatgatttgcaaagatattacaaagtgtaataatgaa
acttcatggacagctttggctagcaacatgtccgacataactacacagaaacatgagagt
agtacggtgaagagccaagtgaccttcaacaagattgaagacactatgtctgtgcgatgc
ctggcaaagaactcccttggggcggtcagccgagaactgaaacttgtggctcctgctatg
cgttccgagttgacggtggcagcctcagttcttgtgttgctagtgattgtcatcttttcc
ctcattatcctgattatcatatggaaacagaaacccaggtatgaaattcggtggagagtc
attgagtccatcagccctgatggccatgagtacatttatgtggatccgatgcaactgcct
tatgactcaagatgggagttccctagagatgggctagtccttggccgaattctgggctca
ggtgcatttggaaaagtggttgaagggactgcatatggattaagccgttcccagcctgtg
atgaaggtggctgtgaaaatgctaaaacccacagctagatccagtgaaaaacaggccctc
atgtcagaactgaagataatgactcatctgggaccccatttaaatattgtaaatcttcta
ggagcatgtaccaaatcaggacccatttatatcatcacggaatattgtttctatggcgat
ttggtcaactatctgcataagaatagagacaacttcctgagccataatccagagaagaca
aagaaagagctagatatctttgggatgaactcagctgatgaaagcacaaggagctatgtc
attttatcctttgaaaacaatggagattatatggatatgaagcaagctgataccacacag
tatgttccgatgctggaaagaaaacagggctctaaatattcagatattcaaagatcaatg
tatgatcgccctgcatcatataaaaagaaatctgaatcagatccagaagtcaagaacctt
ctttcagatgatagttcagaaggtctcagtctcttggatctgttgagcttcacctatcaa
gttgcccggggaatggagtttttggcctcaaaaaattgtgttcaccgtgatctggctgcc
cgcaatgtgcttctggctcaaggaaaaatagtgaagatctgtgactttggcttggccaga
gacatcatgcatgattccaactatgtatccaagggaagtacttttctcccagtgaagtgg
atggctcctgaaagtatctttgacaatctgtacaccacgctgagtgatgtctggtcttat
ggcatcctgctgtgggagatcttttcccttggaggcacgccctatcctggaatgatggtg
gattctactttctataataaaatcaaaagtggataccggatggccaagcctgaccatgcc
accagtgaagtatacgagatcatggtgaagtgctggaacagtgagccagagaagagacct
tccttttaccatctgagtgagattgtggaaaatcttctacctgggcagtataagaagagt
tatgagaaaattcacctggacttcctgaagagtgaccatcctgctgttgctcgcatgaga
gtggagtgtgataatgcttacattggtgtcacctacaaaaatgaagacaagctgaaggac
tgggaaggcaactatgatgaacagaggttgagtgctgacagtggctatatcatccctttg
cctgacattgaccctatccctgaagatgacctaggcaaaagaaacagacacagttcccag
acatctgaggaaagtgctattgagacaggttccagcagctctaccttcatcaagagagag
gatgaaaccattgaggacatcgacatgatggatgacattgggatagactcctcagatctg
gttgaagatagcttcctgtaa
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