KEGG   Macrotis lagotis (bilby): 141520824
Entry
141520824         CDS       T11097                                 
Symbol
CYP11A1
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
mlao  Macrotis lagotis (bilby)
Pathway
mlao00140  Steroid hormone biosynthesis
mlao01100  Metabolic pathways
mlao04913  Ovarian steroidogenesis
mlao04925  Aldosterone synthesis and secretion
mlao04927  Cortisol synthesis and secretion
mlao04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:mlao00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    141520824 (CYP11A1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    141520824 (CYP11A1)
   04925 Aldosterone synthesis and secretion
    141520824 (CYP11A1)
   04927 Cortisol synthesis and secretion
    141520824 (CYP11A1)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    141520824 (CYP11A1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:mlao00199]
    141520824 (CYP11A1)
Enzymes [BR:mlao01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     141520824 (CYP11A1)
Cytochrome P450 [BR:mlao00199]
 Cytochrome P450, animal type
  CYP11 family
   141520824 (CYP11A1)
SSDB
Motif
Pfam: p450 Cytomega_US3
Other DBs
NCBI-GeneID: 141520824
NCBI-ProteinID: XP_074088797
LinkDB
Position
4:complement(48548077..48569624)
AA seq 525 aa
MMLVRGVSHQSALTKGRHCLLGSPREDAWTSTVRRVQLPARGGELGAFPLRAQGPRSFNE
MPCKGVNGWINLLRFWMENGMHNLHIRTMQGFQELGPIYREKLGNADSVFIINPDDAARL
FKAEGPYPERFCIPPWVAYHTYMKKPLGVLLKKGESWKKDRILLNQFVLSLDSVNNFEPL
VTPISEDFVRNIYNKIERSDQGKFTVDLSQDLFRFAFESICNIIFGERLGLLEEFVDPEA
QQFIDAVSTLFETSVPMVNIPPELFRMVRAKAWRDHVASWDLIFERAENYVQNFYQDEKM
RTDMTGNYPGILYSLLRKNIMSFEDVKGNVTEMMAGGVDTTSVTLQWCLYEMARNLKVQD
MLRAEVLAARKNAQGDMKVMLKSIPLLKAAIKETLRMHPIAITVQRYIPSDLVLQDYMIP
AKTLVQVAVFAMGKDPNFFPNPDKFDPSRWLHEETYFRALSFGFGTRQCIGRRIAELEMA
IFLMHILENFKIEVHKLSDVGTTFNLILMPDKPIVFTFRPFKPKP
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgatgttggtgaggggagtctcacatcaatcagccttgaccaagggccgtcattgcctc
cttggctcaccccgagaagatgcctggacatcaactgtccggagagtgcagttaccagca
agaggtggggagctaggtgccttccccctccgggctcaggggccccggtccttcaatgag
atgccctgcaagggggtcaatggttggataaatctactccgcttctggatggagaatggg
atgcataacctgcatatccgaactatgcagggtttccaagagttaggcccaatttaccgg
gagaaacttggcaatgcggactctgttttcattatcaatcctgatgatgctgcccgcctc
tttaaggcagagggaccttacccagaaagattttgcattccaccatgggtggcctatcac
acctacatgaaaaagcctcttggagtcctgctcaagaaaggagaaagctggaagaaagac
cggattttactgaaccaatttgtgttgtctctggactcagtaaacaattttgagcctctt
gtgactccaatttcagaggactttgtcagaaatatttacaataaaattgagaggagtgac
cagggaaagttcactgtggacctcagtcaggacctgtttcgatttgcttttgagtctatc
tgcaacattatttttggggagcgactgggactcctggaagagtttgtggaccctgaagcc
cagcagttcattgatgctgtgtcaacattgtttgaaaccagtgtcccaatggtgaatatc
cctccagaactgttccgaatggtcagggccaaggcctggagggatcacgtggcctcttgg
gatctgatttttgagcgagctgaaaattatgtacagaacttctaccaggatgagaagatg
agaacagacatgaccggcaattatccaggaattctctacagtctcttacgcaagaatatt
atgagttttgaagatgtcaaaggcaatgttacagaaatgatggcaggaggggtggacacg
acttcagtgactttgcaatggtgcctatatgaaatggctcggaacttgaaggtgcaagac
atgcttcgagctgaagtcctggctgcccggaaaaatgcccagggagatatgaaggtgatg
ctcaaatcgattcctcttctcaaagctgctatcaaagagactctgaggatgcaccccatt
gcgattaccgtacaaaggtacattccatcggatttagttctccaggattacatgattcct
gccaaaacactggtccaggtcgctgtctttgctatgggaaaggaccctaacttcttcccc
aacccagacaagtttgatcccagcagatggctccatgaggagacctacttccgggctctg
agttttggctttggcactcggcagtgcattgggcggaggattgcagagttggagatggct
atcttcctgatgcatattctggagaacttcaagattgaagtccacaagctttcagatgtg
gggaccacctttaatctcatactgatgcctgacaagcccattgtgttcaccttccggccc
ttcaagcctaaaccgtaa

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