Macrotis lagotis (bilby): 141521337
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Entry
141521337 CDS
T11097
Symbol
CYP17A1
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase
KO
K00512
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:
1.14.14.19
1.14.14.32
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao00140
Steroid hormone biosynthesis
mlao01100
Metabolic pathways
mlao04913
Ovarian steroidogenesis
mlao04917
Prolactin signaling pathway
mlao04927
Cortisol synthesis and secretion
mlao04934
Cushing syndrome
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
141521337 (CYP17A1)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
141521337 (CYP17A1)
04917 Prolactin signaling pathway
141521337 (CYP17A1)
04927 Cortisol synthesis and secretion
141521337 (CYP17A1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
141521337 (CYP17A1)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
mlao00199
]
141521337 (CYP17A1)
Enzymes [BR:
mlao01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.19 steroid 17alpha-monooxygenase
141521337 (CYP17A1)
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
141521337 (CYP17A1)
Cytochrome P450 [BR:
mlao00199
]
Cytochrome P450, animal type
CYP17 family
141521337 (CYP17A1)
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Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
141521337
NCBI-ProteinID:
XP_074089908
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All DBs
Position
4:112576918..112588022
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AA seq
502 aa
AA seq
DB search
MWWFLTISLLTLLYYTWQKVGSLGKKYPTCLPHIPILGSLPYLNSSDPAHIYFTKLKEKY
GHIYAFWLGPYYSVVVSQFSLAKEVLLKKGKDFASRPRMVTTDILSGSGKGIAFSQYGPQ
WRMYRKLVQSTFSLFKDRPQNFEKIICQEASSLCKSLATKQGQSFDPALDFFLASANVIC
QFCFSSSWKQDDEEIKIMMNFSDAIIKTLAKDNLIDVFPWIQLFPNKDLTLLKESVILRN
KLLEKKIKIQKEKFHIDSINNLLDTLLKAKINNNDHLTQEPEITDEHVLMTVGDIFGAGM
ETTSSVVKWCIAYLLHYPQVKEKIQKEIDQKIGFSRTPVLSDRNQLLLLESTIREVLRIR
PVAPLLIPHMAHTDSSIGEYTIPKGTRIYINLWSIHHDPTEWDEPEQFKPERFLDKNKEH
LIMPTASYFPFGCGPRVCIGEFLARAELFLFLAWILQRFDVDLPDDGKLPSLEGEFGVVY
QIVAFKLKFRLRKAWREAQLST
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
atgtggtggtttcttacaatttccctgctgactctgctatactacacctggcagaaggtg
ggaagtttgggcaagaaatatcccacatgcttgccccatatacccatcctgggaagtctt
ccatatctgaactcctctgacccggcacacatctacttcaccaagcttaaggagaagtat
ggtcacatctatgccttttggctgggtccttattactctgtggtagtgagccagttctca
ctggccaaggaagtactactcaagaagggcaaggattttgccagtcgcccccgaatggta
accacagacatcttgagtggctcaggcaagggtattgccttcagtcagtatggtccccag
tggcgaatgtatcggaagctcgtgcagtccaccttctctttgtttaaggatcgtcctcag
aactttgaaaaaatcatctgccaagaggccagttctctatgtaagtccctggctaccaag
caaggacagagcttcgatccagctttggacttttttctggcttcagccaatgtgatctgc
caattttgcttcagtagctcctggaagcaagatgatgaggaaataaaaatcatgatgaac
tttagcgatgccatcattaaaactctggccaaggacaatctgattgatgtctttccctgg
attcagctattccccaacaaagacctgacactgctgaaggaaagcgtcatattacggaat
aagctactggagaaaaaaattaaaattcaaaaagagaaattccacatagattctatcaac
aacctcctggatacactgctaaaagccaagatcaacaataatgaccatctgacccaggaa
ccagagatcacagatgagcacgtcctgatgacggtgggagacatctttggagctggtatg
gagactaccagcagtgttgtcaagtggtgcattgcctacctgctgcactatccccaggta
aaggagaagatccagaaggaaattgaccagaaaatcggttttagtcgcacccctgtgctc
agtgacaggaaccagctcctcctcctcgagtctacaatacgtgaagtactccgcatacgg
ccagtggctcctttgctcatccctcacatggcacatactgacagcagcattggagaatac
accattcccaaaggcacgaggatctacatcaacctatggtccatccatcatgaccctaca
gagtgggatgagccagagcagtttaagccagaacgattcctggacaagaataaggaacat
ctcatcatgccaactgccagctacttcccctttggctgtggaccccgagtctgtattgga
gagttcttagctcgggcagaattattcctctttctggcctggatcctacagagatttgat
gtggatctacctgatgatggaaaactaccctctttagagggggagtttggagtagtctat
cagatcgttgccttcaaattaaagttccggctacggaaggcctggagggaggctcaactc
agcacctag
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