Macrotis lagotis (bilby): 141521535
Help
Entry
141521535 CDS
T11097
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao01521
EGFR tyrosine kinase inhibitor resistance
mlao01522
Endocrine resistance
mlao04010
MAPK signaling pathway
mlao04014
Ras signaling pathway
mlao04015
Rap1 signaling pathway
mlao04066
HIF-1 signaling pathway
mlao04068
FoxO signaling pathway
mlao04081
Hormone signaling
mlao04114
Oocyte meiosis
mlao04140
Autophagy - animal
mlao04144
Endocytosis
mlao04150
mTOR signaling pathway
mlao04151
PI3K-Akt signaling pathway
mlao04152
AMPK signaling pathway
mlao04211
Longevity regulating pathway
mlao04213
Longevity regulating pathway - multiple species
mlao04510
Focal adhesion
mlao04520
Adherens junction
mlao04550
Signaling pathways regulating pluripotency of stem cells
mlao04730
Long-term depression
mlao04913
Ovarian steroidogenesis
mlao04914
Progesterone-mediated oocyte maturation
mlao05200
Pathways in cancer
mlao05202
Transcriptional misregulation in cancer
mlao05205
Proteoglycans in cancer
mlao05214
Glioma
mlao05215
Prostate cancer
mlao05218
Melanoma
mlao05224
Breast cancer
mlao05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
141521535 (IGF1R)
04014 Ras signaling pathway
141521535 (IGF1R)
04015 Rap1 signaling pathway
141521535 (IGF1R)
04066 HIF-1 signaling pathway
141521535 (IGF1R)
04068 FoxO signaling pathway
141521535 (IGF1R)
04151 PI3K-Akt signaling pathway
141521535 (IGF1R)
04152 AMPK signaling pathway
141521535 (IGF1R)
04150 mTOR signaling pathway
141521535 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
141521535 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
141521535 (IGF1R)
04140 Autophagy - animal
141521535 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
141521535 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
141521535 (IGF1R)
04520 Adherens junction
141521535 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
141521535 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
141521535 (IGF1R)
04914 Progesterone-mediated oocyte maturation
141521535 (IGF1R)
09156 Nervous system
04730 Long-term depression
141521535 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
141521535 (IGF1R)
04213 Longevity regulating pathway - multiple species
141521535 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
141521535 (IGF1R)
05202 Transcriptional misregulation in cancer
141521535 (IGF1R)
05205 Proteoglycans in cancer
141521535 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
141521535 (IGF1R)
05214 Glioma
141521535 (IGF1R)
05218 Melanoma
141521535 (IGF1R)
05215 Prostate cancer
141521535 (IGF1R)
05224 Breast cancer
141521535 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
141521535 (IGF1R)
01522 Endocrine resistance
141521535 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlao01001
]
141521535 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mlao04090
]
141521535 (IGF1R)
Enzymes [BR:
mlao01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
141521535 (IGF1R)
Protein kinases [BR:
mlao01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
141521535 (IGF1R)
CD molecules [BR:
mlao04090
]
Proteins
141521535 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Motif
Other DBs
NCBI-GeneID:
141521535
NCBI-ProteinID:
XP_074090281
LinkDB
All DBs
Position
4:complement(139363611..139752020)
Genome browser
AA seq
1365 aa
AA seq
DB search
MKSGAGRGSPTSLWGLLFLFSTLCLWPTNGEICGPNIDIRNEIQELKRLENCTVIEGYLR
ILLISKAEDYRNFRFPKLTVITDYLLLFRVAGLESLSDLFPNLTVIRGRNLFYNYALVIF
EMTNLKEIGLYNLRNITRGAIRIEKNSDLCYLSTVDWSLILDAVSNNYIVGNKSPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNHCQKMCPSSCGKRACTDQNQCCHPECLGSCS
APDNDTACVACRHYYYGGTCVSTCPPNTYKFEGWRCVDKDFCASVHSAEANEYEKFVIHN
DECMQECPSGFIRNGSQSMYCSPCEGPCPKVCEGEKKTKTIDSVTSAQMLQGCTVFKGNL
LINIRRGNNIASELENFMGLIETVTGYVKIRHSHALVSLSFLKNLRNILGEEQLEGNYSF
YVLDNQNLQQLWDWNLHNLTIKEGKMYFAFNPKLCVSEIYRMEEVSGTKGRQSKGDINTR
NNGERASCESDVLHFISNTTMKNRIKLTWQRYRPPDYRDLISFTVYFKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVKPGILLQGLKPWTQYAIYVKAVTLTMVENDHIRGAKSE
IVYIRTKAAVPSIPLDVISASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKVPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERRRRDVFQIANSTLPSRNRNTTIADHFTNISDTEEIESEYPFYE
SRVDNKERTLISHLRPFTLYRIDIHSCNHEADTLGCSASNFVFARTMPAEGADNIPGQVL
WEPRPDNTVYLKWSEPENPNGLILMYEIKYGQQIEDQRECVSRQEYRKFGGARLTRLSPG
NYSARVQATSLSGNGSWTDPVFFYVPAKPPDYENFIHLMIALPIAGLFILGGILIMWYVY
NKKRNSDRLGNGVLYASVNPEYFSAADVYVPDEWEVPREKITMSRELGQGSFGMVYEGVA
KGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVI
MELMTRGDLKSYLRSLRPESENNPCQMLPTLKKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQYNPKMRPS
FLEIIGSIKDELDPGFKEVSFFYSEENKPPDTEELDLETENMESIPLDPSSTLQQPADKL
SGHKAENGPGVVVLRASFDERQPYAHMNGGRKNERALPLPQSSAC
NT seq
4098 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggcgccggaagagggtccccgacctcactctgggggcttctgtttctcttt
tctacactttgcctttggccaacaaatggagaaatttgtgggccaaacattgacattcgc
aatgaaatccaggagttgaagcgactagaaaactgcacagtcattgagggctacctccga
attctactgatctccaaggcagaggactaccggaacttccgattcccaaagctcacagtc
atcactgactacttgctgctttttcgtgtggcgggcttggagagtcttagtgacctcttc
cctaacctgacggtcatccgagggagaaaccttttttataactatgctctggtgatcttt
gagatgaccaatctcaaagagatcgggctgtataaccttaggaatatcactcggggggcc
atcaggattgagaagaactcagacctctgttacctctcaactgtggactggtctttgatt
ctggatgctgtatctaacaactatattgtgggaaataaatctccaaaggagtgtggggac
ctttgtccagggacaatggaagagaagccattgtgtgaaaagacaaccattaataatgag
tacaactaccgctgctggaccacaaaccactgtcagaaaatgtgtcctagctcatgtgga
aaacgggcctgcacagaccagaatcagtgctgccaccctgagtgcttaggaagctgtagt
gcaccagacaacgacacagcctgcgtggcttgccgccattactactatgggggcacttgt
gtgtctacctgccctcctaacacttacaaatttgagggttggcgttgtgttgacaaagat
ttctgtgccagtgtccacagtgctgaagccaatgaatatgaaaagttcgtgatccacaat
gatgagtgcatgcaagagtgtccctctgggttcatacggaatgggagccaaagtatgtac
tgcagtccctgtgaaggtccttgccctaaagtctgtgagggagagaagaagacgaagaca
attgattctgtaacttcagcccaaatgctgcagggatgcactgtcttcaaaggcaatttg
cttattaatatccggcgaggcaataacatagcctctgagctggagaacttcatgggcctt
attgagactgttacaggatatgtgaagattcgccattcacacgccttagtctccctgtct
ttcttgaaaaacctgcgaaatattttaggagaagaacaactagaagggaattattctttc
tacgtccttgataaccagaatttgcagcagctctgggactggaaccttcataatctgaca
atcaaagaagggaaaatgtactttgcttttaatcccaaattgtgtgtttctgaaatttat
cgaatggaggaagtgtcaggaactaaaggtcgccagagcaaaggggacataaacactaga
aacaatggagaaagagcctcttgtgaaagtgatgttttgcatttcatttccaacacaaca
atgaagaaccggattaagctaacatggcaacgatatcgtcctcctgattacagggatctt
attagctttactgtttacttcaaagaggcaccattcaagaatgtcactgagtatgatggg
caagatgcatgtggctccaacagctggaacatggtcgatgtggacctccctccaaataag
gatgtcaaaccgggaatcttacttcagggtctgaaaccatggactcagtatgctatctac
gtcaaagcagttactctcacaatggtggagaatgatcacatacggggagcaaaaagtgaa
attgtatatattcgtaccaaagctgcagttccttctatccctttggatgttatttcagca
tctaactcatcctctcaattaattgtgaaatggaatcctccttccctcccaaatggcaac
ttgtcctactatatagtaagatggcaacggcaacctcaagatagttacctctaccgacat
aattattgctccaaagacaaagttcctattagaaagtatgctgatggcaccattgatgtt
gaggaggtcacagaaaaccctaaaactgaagtctgtggtggggagaaaggaccctgttgt
gcttgtcctaagactgaggccgagaagcaagcagagaaagaagaagctgaatacagaaaa
gtctttgagaattttctgcacaactccatctttgtacccagacctgaacggagacgtagg
gatgtctttcaaattgccaattccactttgccaagtcggaacaggaacaccacaatagca
gatcacttcactaatatatcggacacagaagagattgaatccgaatacccattctatgag
agcagagtggataataaagagaggactttaatttctcatctcagaccttttactttgtac
cgaattgatatccatagctgcaaccatgaagctgatactcttggatgtagtgcttctaac
tttgtctttgcaaggaccatgccagcagaaggagcagataatattcctgggcaagtattg
tgggaaccaagaccagataacactgtctatttgaagtggtcagaacccgaaaatcccaat
ggactgatactaatgtatgaaataaagtatggccagcaaatagaggatcagcgggaatgt
gtttccagacaggaatacaggaaatttggaggggccaggcttacgcggttaagccctgga
aactattcagcccgtgttcaggctacctctctttctgggaatggatcatggactgatcct
gttttcttctatgtccccgccaaaccaccagactatgaaaacttcattcacttaatgatc
gctctacccatcgcaggattatttatacttggtggaatactgataatgtggtatgtctac
aataaaaaaagaaacagtgacagattagggaatggagttctatatgcatctgttaatcca
gagtacttcagtgctgcagatgtgtacgttccagatgaatgggaggtacctcgagaaaag
atcaccatgagtcgagaacttgggcagggttcatttgggatggtatatgagggagttgca
aagggtgtggtgaaagatgagcctgaaaccagagtagccatcaagacagtcaatgaagca
gcaagcatgcgggaaagaattgaatttctcaatgaagcttcagtaatgaaagaattcaat
tgtcatcatgtggtgcggttgcttggagtagtgtcccagggccagccaacattagtcatc
atggaactgatgactcgaggggatctcaaaagttacctcagatctctgaggccagagtca
gagaataatccatgccagatgcttccaaccttaaagaagatgattcagatggctggagag
attgctgatggcatggcctatctcaatgccaacaagtttgtccacagggatcttgctgca
aggaactgcatggtcgctgaagatttcaccgtcaaaattggagattttggtatgacaaga
gatatctatgaaacagattactaccgaaaaggaggtaaaggattgttacctgttcgctgg
atgtctccagagtcacttaaggatggagtcttcacaacacattctgatgtttggtccttt
ggtgttgtcctctgggagattgcaacattagcagagcagccctatcagggcatgtctaat
gaacaagttctccggtttgttatggagggtggccttctagagaaaccagacaactgcccc
gatatgctctttgaattgatgcgtatgtgctggcagtacaatcccaaaatgagaccttct
tttctggagatcatcggcagtatcaaagatgagctggacccaggcttcaaggaggtctcc
ttcttctacagtgaagagaataagcctccagacacagaggagttggacttagagactgag
aacatggagagcattcccttagacccttcctccaccctccagcagccggctgacaaactc
tcaggacataaagccgagaatgggcctggtgtggtggtcctcagggccagctttgatgaa
agacagccttacgcgcacatgaatggaggacgcaagaacgaaagggccttacctttgccc
cagtcttcggcctgctga
DBGET
integrated database retrieval system
