Macrotis lagotis (bilby): 141522494 Help Entry 141522494         CDS       T11097                                  Symbol SYNE2 Name (RefSeq) nesprin-2 isoform X1   KO K19346   nesprin-2 Organism mlao  Macrotis lagotis (bilby) Pathway mlao04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:mlao00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     141522494 (SYNE2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:mlao03036]     141522494 (SYNE2) Chromosome and associated proteins [BR:mlao03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     141522494 (SYNE2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin_SYNE1 CH KASH Spectrin SYNE1 CAMSAP_CH Motif Other DBs NCBI-GeneID:  141522494 NCBI-ProteinID:  XP_074092080 LinkDB All DBs Position 4:267667859..268082306 Genome browser AA seq 7106 aa AA seqDB search MASGPMAPTKDEKLSSGIDDLHFSLQAEQENTQKKTFTSWINAQLAKHIPPSVITDLFTD IKKGHVLLDLLEVLSGQQLAREKGSNTFQCRSNIEHALTFLKKRSIKLINIHVTDIVEGN PSIILGLIWTIILHFHIEELAWILSCNYNQPSLDCVSVVDLSQTSGPLPKKRSKAQARWK MSAKKALLLWAQEQCCMHESVNVTDFKSSWRNGMAFLAIIHALRPDLIDMNSVKGRSNRD NLKEAFRIAERELNIPTLLDPEDVDVINPDEKSIMTYVAQFLQYSKDLPVAGDEVQEKVK DATVWLISQEEKLHELQMESETETYFKKSQGMRTFLESFNEEKKAFLDVLSIKRNVAGLA DDQSRLRQAWDKLTNQINEWSAKLDQILPPPLDQIEVWLQEIEHLMAEDLPDSQDYSQVM VLIKERINSFKSLMDDFDRHLNSLLTFENKDEQHMPMVPPDKLEEMKRRFHNIMGTNFIA LSEFHYYLYSVLGLIEQVKLKLNLWNIKYGTQESVEILLGDWHKFIEEKEFLTQLESSFQ KCEIMIKNLAGDPQNINKQFKMVESQTSMCRKCMYNIKSTLQRVLSSWATYTENLHSLKT WLEESRKEHPKQVPFETLASWNSVLSTINEVGKYLIDVSNQQVGLSINKELKRLNKRWAK FIKKTQFEMKFCFAQEQEQLSLDNTGNAELPLEENLTSYGGSTDISTEVLRKHIQHLKTR KENEVVIKEFTELLQVLEEMEEFIDQVATWEIEIRPVLDFIKHQGYVEASMEESLQNLIA RGSMYQEHVTRKENALQIIAQNISSKALFQHFHTSGLQTQIKEAKDKVQNNMAELDAVLQ ASYESSLEMDVRVKFEKSQKELESDITKAQQLLRQKGKLGDLISQKKDMLAILNSKSLDK FLKVAEQLKNIVSPDEKLSLEEMSREFSKEWKNLLKEIDLYIHRIKIEIEKKISENISKL EKQLNKEKKLLNKGKTKGLIEEHEACFSDEGILCQLDHHMEALRELSEELTLEESQQEIR KTIIEYGQRQNGIKNTASEIYMMLKTLIENTQMSEKKKSLSVSENGGRDSGKMAQPSKPN DAPSSEEASGPASFDLEYFSILKHHEDERHTEKDGDMPFKKLVERYDAQRDNLELQLQNN EVRILSDFPSEKERSISCLQDKLTDLQVLKNGTDSCWTEFEMTSLKLENIVRDPERFVLS QTRDKLKRKEEELQVTLSNRMKSLEAALRIVLPIEKEAVILGDSEQFLHKMDIQEFNLPG ADEAHQNLKDIQSNIAKQIELCSKLEHPNSDTLNEFNPIDLHATQSIIVKYKMQFEEMNH KMYSTETALKTLEDFLTSMREAKLSIQPTIDFLTSDISVLQENTWTIEDVQKKIPLMREE ARCLDQHMKMLDISLKNAEQGEDTCCEKLIEIFSKMIDETHGQNKPEDLTEQDQLVEVFN SKNNEILKNIKYIQDQINKVGLKDPTIPAVKQRIKSLTKLEKDLDYYAGKINHLRKMADS LPQLKDEKGEIPSQQYQETTYLCEDIKSSVEESLEQCQRAMELLKQYQNCKSILTSLIHK EESVISLKTSYMGKENLKRRIAKIEIVKEEFNKHSEDVEKINQICKNLQFQLNKMITFEE PPFEKEANVIVDRWLDINEKTENYYDNLVRALALWEKLLNLTNIIDEWIEKVLRKVEVHQ MNDTERIQLQEELKLQEQNSAKFSTKLTEIEDLLQISEPPLELQVIKSSLLNRIEKIKIH LMDKSNLSELVGNTAELKEDLDQAKTQIGMTESLLKALSPSDSLEIFTKLEEIQQQILQQ KHNMTLLENQIGCLTPELFELKKQYESINDLFSTKKRTLQDHFSNLLNDQCKNFEDEFNN IQLSLKECFEPPETKKNVEEKLQKLNDFLTLEGRSKAIQQIEIALINVKRYLPKESVKQL STWIMTQELDLQKMKFTCETQIKELHDCLQQLLRLQEDYISLNKWLMNQEEKWKETGIET KSNFFCQALTRKRQLFETFAQLNDSLKKSGLIREEIVIESTHLVEKYETFLIQVCKTENY QSPPAEDQNFEDLVQDVFSWIMGIKESLMVLNSTEGKMPLEERIQKIKEIILLKPEGNVK IQHIMSLGEKSKASMVQDTLSDIKNQWDHTIHLANTYLSHQEKILLEGEKYLQSKDDLRL MLTELKKKQESGFALQNGLQEKKAQLKIYKKFLQKAEDLTCLLNELKTQGNYLLECTKNS KFSEEKWLEVKYLHESLLHQLQDSVSKLEGHVQAHQLYQDLVEDLSTTLESFSQEFFSFP AILVDEKAVEQKVLKLQELEVLLNLKGDTLEEILALAESIKQNSSSVGQKIIKDETDSLK CKHKDLKNSLESVKQETENSFNNILKSKSEMKKKEKIAMKKREEQVYFGTQESIQGSITV EKLEESWEVNKVGELNEKDMDKEPPKKLHMKDNLAECLPQPPIQEKNGENLTAQDELSSK QEHVETMDTENHTIEPNIFKKNSLSESTEIMVKIKEESDVMLVAHKSQCESAEDNLKINQ MNNQISNIPNVVQEKLMINQTSVEELETKEPLRTENQVESLEKSMDINDQTYRRIVQDFQ LWLSSMEQLLGFIVEEQQEEPAPGKTLSIFETSDIEMLLSKQLFPGAQESMKNIEDEQRV NELQNQPLELDIISANEQLKEIEVWCGQLEAKKANIGSQESVILPRKTESRTLDVQNIQY SVDQLDRLLQALVTLKEDKERQYSLIKDFQEQLLAVKSSMKAISMEKESIKVASLESIQH LEKLEKCLESLHKVKDSLNKLKEEQVHLLSPLNDMDKKLAESQVKQLELCWEEVEQWIQK KYSQQGAQWDELQYLMGKIQDMENSLQEQQQQQQQNLNFPSEQGENKGPVLLITKLQVIK DNFSILKGRIEHQMKRIWGKKEKKIFENAINYLQEQLEALEPSTAEKDNQLKRCPTMKKI QEAVLWVNNLLIDLEQTVALLPDNIVSQIRKQKTVYDEVLVKQPIIESLVEETEDVISDL SQCEAIDLNTYSQELQSSNQALASKCIEMSQQLESKLEERRTFFEKMGKVQSSLQGKEIL IAPDAKTTFSKEDLNHQLVTLKDSQKELQMTEGVISTLLQEAKDFSRSLNVFERVFLDDQ LRNHKNKVRRTQRLVQNKCHEVRTKLDTYTELLEKTNMLEQELNEIHNHEFLLTRDVNQR TKEEICELKERTYVLQSNVLQIVKHKEIFECLGLIWDSSLFDKVQAELLKIKTELEEKAK QLEKVITANERLQMSLNELKKVTLQIKKETAEIVNDPNFSPKSSLLSAQILNQNVEKATY LCQEILDLINANETCKESFKQEIPQIEFLVEEKDKLHKSLQNMIENFQPQSVSEKDFSDQ LEHTLQVLTQANFQLQQPLQIGLEIKHIQEEKDICEVLQKRIMTELCKIKAITVKKCPRQ EENLNETKDLETKLNKLEDLQIQFNTGIALRKNILDEALKDMKNFSEAITRAVEIINSFK TTVDSFKIDLDNIGKFQQLIDSKQEEFEVLVVDLKNLISKLENITNPKAKVQLEHVLQGL FNNNSLVKELAETKKADLERYLKSYESYNKIKQKICANLNKVEKGLQLSISQEPMSYREA LEHLEHSKNFVADLVSTQEELMKLRQDMRCLRLMCTENDSICLFKIVSALWERWLSLLEK AKEWELYCEELKQEWKFVSEEIEREAIILDNLQEEFPEHTKLKEAATNEELSETQEFYSQ YEENLEREQLLFTLLLHRIKNVMNVPENLKTIESIPVLQEIWSMQERCTKLSQKAQGNKK LIQFEIEERNNISKEIIALKNSFEKMTASFHNMALEENPEKENQLEALQRIIDKEKLALE NIMEKLRIKYSEMYTIVPAEIECQMEECKKTLEDIDEKIRNEALKSSPSYVMSRKIEEIN HGLQNVEKMLQQKSKNIEQAQEIQKKMWDELDLWHSRLNELDSEVQDIVEQDPGQAQEWM DNLMVPFQQYQKVSQRAEHRTSQLNKATLKMEEYNDLLRNTETWIENTTSLVDDPIDYSS SKVLSHHANILQMALEDSEQKQNLLHSVYSDLEEFSVIFETDDLAPIKLNQLSARVTILQ QKLMASLPQIQHMADEVVAIETEVKSIEKKVSKIKAILFSKEIFDFSPEEHLKHGEVILE NIKSMKKSIAEIESYQVVLAVPETGVKSLSVFERTNQLSQVVKMLEKVTHEQNELLKIVM KQTDEYDQEIENLKHQLKNYSTEFSSENISPDQAITLSQGQRETDGIKEQILDLNQKKED LLIGLKTKVLALHQHFQQEKQELEKETEESGVAERDVSEWKLKRKGSMFLPPSIVEETEE SSQKSENGDEKAESASSTYLLHCGHERNKEEDRASSSSGTLIQEADGRISTYDGYNTQIF DPNPLKNEQNPNSSPIHIQQEVGDTASSGAPAQSPGEQGSLEETVARSRPESVEILHVCQ QQVAELEQWLEKANLSFRAETLNAEMQQMVEQELAGCQAMLTEIEHKVSFLLENCKDQSL GNSGSTQQEAEMLSLKLKAVKCNLEKVQVMLQDKYSEEQRSNTLKKSSEDQKIFQSDRSP VFESITFENPLFSRQKSFQQQALELKPGEQKDLIKFIEIHAEKMLHQQDQQDDSKTQESL VNPGASHSTYGSTKSFLPSQEQSEDKWKYLLQELLKEKLPPPQPVDQIAANVNFLPMVPV HNIRSPTVEELKTYTSQVEDLSQEANVLHIQENLTSESSLSLDRKIFDLLLSISQCLSIV EEMLQISGLSREDTAVQHAHYEMLSLELRKLHSAITNKKDDLLKLISHPGKSSSVFFECF NNLQTRLEQTQAAAFSRSQSMKSGIENNSDYQSQVRELYDQLIEKKSSVQHSLNEISSQS IVEQLQKADLYAIKLQDYEVQVAKLRDEGERLYLPYVLIQEVYKLEDVLDDMWGLLRAKH AELNSPFISESQQEGLLKGLTELVNTGKEKLDQGQQWQAKSKASLQAQLQNHKIFFQKLV ASVFLIQEYFKKAQPSLLQNKEKFCADKVKEVKLLEQQAFQHGSKLENLLQEWKEFEVNY ESLEKDLEILGSSLPSTSLVEETEERLMERISFYQQIKRNIDEKQNKLYQTMNEGKYLVT AVSCPELESQIAKLEEQWLALNKKVDHELHRLQTLLKHLVSYNKDSDELTKWLESAQQTL NYWKEQSLNVSQDLDKIRSNINDFFEFSKEVDEKSSLKTSVISTGNQLLHLKETDTATLR SSLAQFEQKWATLITQLPDIQEKLHQLQMEKLPSCKAITEMINWMDSIEQQIADEATVDL PSSVIQVKNLLQKYKEFRMEMNYKQWIIDFVNQSLLQLSTSDVESKRYERTEFAERLGEM NRQWHKLHGTLNRKIQHLEQLLESITESENKIQTLRNWIEAQGERLKTLQKPGSVISARK TLLDCQDLENHLTSKSRTLDELKENYMALESGPVPVLQDTISGIAGLYQMRNNIANQVNQ LKTSMQSILQQGKGYDKLFEEVNMLTIRFWYCLEHSKPAMLTLEALRCQVKNLQLLQDEA ESSEGNWSKLQNAISKLKDYCPSVTEIIEQKYQEAHTRWTLVNHEIADQLQSAQSMLQLW ESYTIAHAEGTAKLEQLEEKFKHILNINMSGDNLTENLIQALKNAKNLHHDLENVKETFL QNSATIGPKLEQASPVKEDVVSSQSSSLQRISYLEKMLLMKSNEFEHVLSQLKDFRDQLE SLECSVKHLIETLDLQGREDNTEFFLNHMLELTALSPDMEHLNEVSFKLPLSDIDIKTLQ NLNRKWTQATATALEKCSELQGTEFNEKFLHKFEKWIQFLEKIEECLKMNLTGRLEDLLE QQKTFEMLQAEISVNQPIADYFVTQSLQLLDTPEIEKRTEFVMKLTMLKERWQGATRRAQ QRKITINERVKEWRHFNASLQNVTHFLIDTDHFLSAVKSRESYSLCQIRSFIHDLKNKEV LLQRRQTTFALTLDAGRKLLTVADLETKNSIDREIRKLQDGWRNCQLQVAEMTKEFQSTI ETWDQCEKQIKELESRLQTLKAKIKDPLPEPYEELYKEKELIKELENSLANWVQNLKELK IMKADITRYILVEDVMVLKEQIDHLHRQWEELCLRVSLRKQEIEERLNSWIVFNEKNKDL CAWLVQMENKVLQTADISIEEMIERLQKDCMEEINLFSENKLHLKQMGDQLIKASNKTRV AEIDEKLSKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRSWLARIESELSKPV VYDICDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQT TRSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAEKTAAYPNSSEVLY TSAKEELKKFEAFQWQIHERLTQLELINKQYRRLARENRTDTASKLKQMVHEGNQRWDNL QRRVTAILRRLKHFTNQREEFEGTRESILVWLTEMDLQLTNVEHFSESDVDDKMRQLHGF QQEITLNTNKIDQLIVFGEQLIQKSEPMDAVLIEDELEELHRYCQEVFGRVARFHRRLTS HNPGLEDEKEASENETDVEDSREIQSDSWHKKEVNEGPSSPQSLCHLMPPPLSHERSGCE TPVSVDSIPLEWDHTGDVGGSSSHEDDEEGPYYSAMSDVEITENPEAYLKMTTKTLKASS GKSISDAHGWHTPDSPTHQKHHYKPTEVDRNEPETSTPYKPEYVKQLIPPGMDSVDSGRE GPEMLIASEQKGLTDTEQEAGVFDSWELIQAQDLRNKFRTKQNLQQWQQLDSDINDATLW LKGTETELEKLEMMKPAADIQETECRVKRFKDILKAFDNYKALVISINLSSKKFQQPDHT ESKELQNRLRQLNLLWEKANHLLDSWRESLRHSLMQCQDFHQLSQSLLLWLASAENRRCK AQVDPNADPQTILESQKELMQLEKELLEQQLQVNSLQEISKYLLAKGDGEDYIEADEKIH VIGKKLNQLLDQVSQDLESFQENQDEDTTLTALDDVDSNGHHLSSDSVPTSQEKAGAERI TEEKSKKNSRVEHLSDPASTPTSSGPRSFLYRVFRAALPLQLFFLLLLLLACMIPSSEED YSCTQANNFARSFYPMLRYTNGPPPT NT seq 21321 nt NT seq  +upstreamnt  +downstreamnt atggcatctgggcctatggctcctactaaagatgaaaagctttcctctggcatcgatgat ctccacttttcactacaagctgaacaagaaaacacacagaagaaaacctttacaagctgg ataaatgcacagttggcaaagcatatccccccatcagttataacagatctcttcacagat atcaaaaaaggacatgttcttctggatctgttggaagtactttcaggccaacaattggct cgagagaaaggatctaatacttttcagtgcagaagcaacatagaacatgccttgacattt ctgaagaaacgatcaatcaagctcataaatattcatgtaactgatattgtagaaggaaat ccatctatcattcttggtctgatttggacaattatattgcactttcatattgaagaactg gcttggattctttcttgcaattacaatcaaccttctttggattgtgtgagtgttgtggat ttatctcaaacttcaggacctctacccaagaaacgctctaaagcacaggctagatggaaa atgtcagcaaagaaggcccttcttttatgggcccaggaacaatgttgcatgcatgaatca gtgaatgttacagattttaaatcaagctggagaaatgggatggcatttttagcaatcatt catgctttgagaccagacctaattgatatgaatagtgtaaagggtagatccaacagagac aatctaaaagaggcattcaggattgcagaacgtgaactaaacatccccacactgttggat ccagaagatgttgatgttatcaacccagatgaaaagtcaataatgacctatgtggcccag tttctacagtattccaaagatttgcctgtggctggagatgaagttcaggaaaaggtgaaa gatgccacagtctggttgatttcacaagaagaaaagttgcatgagttacaaatggaatca gaaacagagacatactttaaaaaatctcaaggtatgcgaacttttttggagtctttcaat gaagaaaaaaaagcatttttggatgtgttgtcgataaaaaggaatgtagctgggctggct gatgatcagtctcgattaagacaagcatgggataaactcactaaccagattaatgaatgg agtgcaaagctggatcaaatcttgccccctcccctggatcagattgaagtctggctccaa gaaatcgaacatcttatggcagaagatttaccagattcccaggattacagtcaagtcatg gttctaatcaaagaaagaatcaattcatttaagagtctaatggatgattttgatcgtcat ctgaacagcctcttgacatttgagaataaagatgaacaacacatgcccatggtcccacct gataaactggaggaaatgaaaagaagattccacaatattatggggaccaacttcattgca ctttcagaatttcactactacttgtactctgtcctgggtttaatagagcaagtgaaatta aaattgaatctctggaatatcaaatatgggacacaggaatctgtggaaatattattggga gattggcataaatttattgaagaaaaggaattcctaactcagcttgaaagttcttttcaa aaatgtgaaataatgataaaaaatttagctggagatcctcaaaacattaacaagcagttt aagatggtagaatctcagacttctatgtgtagaaaatgcatgtataatataaaatctacc ttgcaaagagttctgtcatcttgggctacatatacagagaaccttcattcactcaagact tggttggaagaatcaagaaaagaacatccaaaacaggttccttttgagactctagcaagt tggaattcagtgcttagtactataaatgaggttggaaaatatttaattgatgtcagtaac caacaagttggattgtctattaataaggaactgaaaagacttaataaaagatgggcaaaa ttcattaagaaaactcaatttgagatgaagttttgttttgcccaagaacaggagcaactc agtcttgataacactggaaatgcagagttacctttagaagaaaatttaacttcttatggt ggttcaacagatatttcaactgaagtacttaggaagcacattcaacatttaaagactaga aaagaaaacgaagttgtaattaaagagtttacagagctcctacaagtgcttgaagagatg gaagaatttattgatcaagtggcaacctgggaaatagaaataagacctgttttggatttt atcaaacaccaaggttatgtggaggcttccatggaagaatctttgcagaatctgattgcc cgaggatctatgtaccaagaacatgtgactaggaaagaaaatgcattacaaataatagca caaaatatttcaagcaaagcactcttccagcatttccatacatctggactccagacacag attaaagaagcaaaagacaaagttcagaataacatggcagagctagatgctgtactacag gcttcatatgagagttctctagaaatggatgttagggtcaagtttgaaaagtcacagaag gaacttgagtcagatattacaaaggctcagcaactccttagacaaaaaggaaaacttgga gacttgatttcgcaaaagaaggacatgctagccattttaaacagtaaaagcttggacaaa tttttgaaagttgctgaacaacttaaaaatattgtatctcctgatgaaaagctatcctta gaagaaatgagcagagagttttctaaagagtggaagaatcttcttaaagaaatagattta tatattcatcgaataaaaattgaaattgaaaaaaagatttctgaaaacatatcgaaactt gaaaagcaactaaataaagagaaaaaattactcaataaagggaagaccaagggactcata gaagaacatgaggcttgcttttctgatgaagggatcctgtgtcagcttgatcatcacatg gaagccctgagggagttgagtgaagagctgactttagaggaaagtcaacaagaaataagg aaaacaattatagaatatggacaaagacaaaatggaattaagaatactgcttctgagatt tatatgatgctcaagacccttattgaaaacactcagatgtctgaaaaaaagaaatctcta agtgtatctgaaaatggtggaagagattctggaaagatggcacaaccttccaaaccaaat gatgcaccttcttccgaagaggcttctggacctgctagctttgacttagaatacttcagc atactaaagcatcatgaagatgaaaggcatacagagaaggatggtgatatgccttttaaa aagttagtggaaagatatgatgcacagagagacaatctagagctgcaattacaaaacaac gaagtcagaattctttctgattttcctagtgaaaaggaaaggagcatctcttgcttacaa gataaattgacagatctacaggttttaaaaaatggaactgattcttgttggacagagttt gaaatgacttcactaaaattagaaaatattgtgagggacccagaaaggtttgttctttct caaacaagggataaattaaagagaaaagaggaagagcttcaagtgactctgagcaacagg atgaaatccttagaagctgcactgaggattgttttgccaatagaaaaggaagctgttatc cttggtgactcagaacaattccttcataaaatggacatacaagaatttaatctacctggt gctgatgaagctcaccaaaatcttaaggatatccagagtaacatagcaaaacaaattgag ttatgtagtaaattggaacatcccaacagtgatacattaaatgaatttaacccaattgat cttcatgcaactcagagcattatagtaaaatataaaatgcagtttgaagagatgaaccac aaaatgtacagcactgaaacagccctcaaaactcttgaggactttttgacctccatgaga gaagctaaactttctattcagcctacaatagattttttgacatcagatatatctgtgttg caagaaaacacctggacaatagaagatgtgcagaaaaaaattccactaatgagagaggag gccagatgtttggatcagcatatgaaaatgcttgatataagcttaaaaaatgctgagcag ggtgaagatacttgctgtgaaaaactcattgaaattttctcaaaaatgatagatgagact catggtcagaataaaccagaggatttaacagaacaagaccaattagtagaggtttttaat tcaaaaaataatgagatccttaaaaacattaaatatattcaggaccagatcaataaagtt ggcctcaaagatccaacaattccagcagtgaagcagaggataaaatcactaaccaaactg gagaaggatctggattactatgcggggaagataaatcacctcagaaaaatggctgattct cttccacagttgaaagatgaaaaaggagaaatcccaagtcaacaataccaagagacaaca tatttatgtgaagatataaaatcctctgttgaagaaagccttgagcagtgccaaagagca atggagctcctgaagcaataccagaattgcaaaagtattctgacctctttgatccacaaa gaagagagtgtgatctcattgaagacttcttatatgggaaaggaaaatctgaagaggaga atagcaaagattgaaattgtcaaagaagaatttaataaacattctgaagatgtagaaaaa ataaaccagatctgcaaaaacttgcaattccagctaaacaaaatgattacctttgaggaa cccccctttgaaaaagaggctaatgttattgtggacagatggcttgatataaatgaaaag acagaaaactattatgataatctggtcagagctctagccttgtgggaaaaacttcttaat ttaacaaatataattgatgaatggattgaaaaagtacttagaaaagttgaagttcaccag atgaatgacacagaaagaatacagttgcaggaagagctaaaacttcaagagcaaaacagt gcaaaatttagtacaaagttaactgaaatagaagatcttcttcaaatcagtgaaccacct cttgaattacaggtcattaagtcatctcttttgaacagaatagaaaaaataaaaattcat ttaatggacaaatccaacctgagtgaacttgttggcaatacagctgagctaaaagaagac cttgaccaggccaagacacagattggaatgactgaatctctcttaaaagccctgtctcct tctgacagtttggagatctttacaaaactggaggagatacagcagcaaattctccagcaa aagcataatatgactcttcttgagaatcaaataggttgtctcactcccgaactctttgaa ctgaagaagcagtatgaaagcataaatgatttatttagtactaagaaacgtactttgcaa gaccacttttccaatctactgaatgatcagtgcaaaaattttgaagatgagttcaacaac attcagctatcacttaaggaatgttttgaaccaccagaaactaaaaagaatgtggaagaa aagctccagaaacttaatgattttttgacccttgagggaagaagcaaggccatacaacaa atagaaattgcactgattaatgtaaaaaggtatctgcccaaggaaagtgtcaaacagctg agtacctggatcatgacccaggaattggatctacagaaaatgaagttcacatgtgagacg caaatcaaggaacttcatgactgcctacaacagttacttaggcttcaggaggactatata agcttgaacaaatggctaatgaatcaagaagaaaaatggaaagagactggcatagaaact aaaagtaattttttctgccaagcattaactagaaaaaggcaattatttgaaacttttgct caattgaatgactcattgaagaaatctggacttatcagagaagaaatagtgatagagtca actcatttggttgagaaatatgagacatttttaatacaagtttgtaaaacagaaaattat cagtcacctcctgctgaagatcagaactttgaagaccttgtacaagatgttttttcttgg ataatggggattaaagagtcacttatggttttgaattcaactgaaggcaaaatgcccctt gaagaaaggatccaaaaaataaaggaaataattttacttaaacctgaagggaatgtgaaa atacaacatatcatgagtttgggtgagaaaagcaaggcgtctatggttcaggatactctg tctgatatcaagaatcagtgggaccacactatccatttagccaatacatatctgagccat caggaaaagattctgcttgaaggagaaaagtatttacaaagcaaagatgacttaagacta atgcttactgaattaaagaagaaacaagaatcaggttttgctttacaaaatggtttgcaa gaaaagaaagctcagttgaaaatatataagaaattcctacagaaagcagaagacttgaca tgcttgcttaatgagttaaaaactcaaggaaattatctcctggagtgcactaaaaactct aaattcagtgaagaaaaatggctagaagtcaagtatctccatgaaagtctccttcaccaa ttacaggattcagtgagtaagttggaaggtcacgttcaagcacaccagctgtaccaggat ttggttgaagacttgagtaccacattggaaagtttttctcaggaattcttcagttttcct gctatcctggtagatgaaaaggcagttgagcaaaaggtgttaaaattacaggaactagaa gtcctccttaatctaaagggtgacacattagaagagattttagctttagctgaatctatc aaacagaactcctcttcagtgggacagaagattattaaagatgaaacagattcacttaag tgtaaacacaaagatttgaaaaatagtcttgaatctgttaagcaggagactgagaacagt ttcaacaacatcctcaaatcaaaatctgaaatgaagaagaaagaaaaaatagccatgaaa aaaagagaggagcaagtttattttggtactcaggaatcaattcaggggtctatcacagtg gaaaaattggaagaaagctgggaagtcaacaaggttggagaattgaatgaaaaggacatg gataaagaaccacccaagaaacttcatatgaaagataatctggcagagtgccttccacag ccccccatccaggagaagaatggagaaaatctaactgctcaggatgaactgtcatcaaaa caagaacatgtggaaaccatggacactgaaaatcatactattgaacctaatatctttaag aaaaattcactatctgagagcacagaaataatggtcaagatcaaagaagaatctgatgtg atgcttgtagctcataaaagtcagtgcgaatctgcagaagataatttgaaaattaaccag atgaacaatcaaatctcaaacattccaaatgttgtccaagaaaaattgatgataaatcaa acctctgtggaagaactggagacaaaagagccactaagaactgaaaaccaagtggaatcc ttggaaaaatccatggacataaatgatcagacctataggagaattgtacaagacttccaa ctgtggttgagtagcatggaacaactcctgggctttatagtagaggaacaacaagaagaa ccagctcctggaaaaactctttcaatttttgagacttcagatatagaaatgcttttgtca aaacaactttttcctggagctcaagaaagcatgaaaaacattgaagatgagcagagagtc aatgagctgcaaaatcaacctttagaattggatattatttcagcaaatgaacaattaaag gagatagaggtgtggtgtgggcaattggaagcaaagaaagccaacattggatctcaggag tctgtcatattgcccaggaaaacagaaagcaggactttggatgtacaaaatatacaatat tcagtagaccagttggacagactacttcaggcactggtcaccttgaaggaggataaagaa agacaatattctcttatcaaagatttccaggaacagctcttggctgttaaatcatcaatg 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aaactaaaggaagcagccactaatgaagaactttctgaaactcaagaattttattcccaa tatgaggagaacctggagagggagcaactgctatttactttacttcttcaccgaataaaa aatgtcatgaatgttcctgaaaatttaaagaccattgaatctattccagtattgcaagag atttggtccatgcaagagcgatgtaccaagctctctcagaaagctcaaggtaataaaaag ttgatacagtttgaaattgaagagagaaataacatcagtaaagaaataattgctttgaag aattcatttgaaaaaatgacagcctcattccacaatatggcattagaagaaaacccagaa aaggaaaatcaattggaggctcttcagagaataattgacaaagagaagctagcacttgag aatattatggaaaaactccgaatcaagtattctgagatgtataccatagttcctgcagag attgagtgccagatggaagaatgcaaaaaaactttagaagacatagatgagaagattaga aatgaagccttgaagagttcaccttcttatgtgatgagtagaaaaatagaagaaattaat catgggcttcagaatgttgaaaagatgttgcaacagaaaagcaaaaatattgagcaagct caagaaattcaaaagaaaatgtgggatgaactagacctctggcattccagactaaatgaa ctagattctgaagtgcaggatatagttgaacaagatccaggacaggcacaagaatggatg gataacttaatggttccttttcaacagtaccaaaaggtttcacagagagcagagcataga acttcacagttaaataaagccacacttaaaatggaggaatataatgatctcttaaggaat actgagacttggatagaaaatactaccagtttggtagatgaccctattgactatagttct tcaaaggtcctgagtcatcatgctaatatccttcagatggctttggaagattcagaacaa aaacaaaatcttctccattcagtttattctgacttggaagaattttcagtgatttttgaa acagatgacttagcaccaattaagttaaatcaactaagtgctagagtcacaattctacag caaaagctaatggcaagtcttccacaaatccagcacatggctgatgaggtggttgctatt gaaaccgaagtaaaatcaatagagaagaaagtctcaaaaatcaaagctatcctgttttcc aaagaaatatttgatttttctcctgaagaacatcttaagcatggagaggtcatacttgaa aacataaagtccatgaagaagtccattgctgagatagagtcttaccaagtggtcctggct gtacctgaaacaggagtgaaatctttgtcagtatttgaaaggacaaatcagctttcacaa gttgtgaaaatgttagaaaaggtgacccatgaacaaaatgaactattgaagattgtcatg aaacagactgatgaatatgaccaagaaatagaaaatttgaagcaccaattaaaaaattat tcaactgaattttcctctgaaaatatatctcctgatcaagctatcaccctgtcccaggga cagagagaaacagatggtataaaagaacagatcctggatttgaatcagaaaaaagaagac ttattgataggcttgaagacaaaagtcctggctctccatcagcattttcagcaagaaaaa caagaattagaaaaggaaacagaggaatctggagtggctgagagggatgtttctgaatgg aaactgaaaaggaaaggatccatgtttctcccaccatcaattgttgaagagacagaagaa agttcacaaaaaagtgaaaatggagatgagaaagcagagtcagcttctagtacttattta 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ccacctcaacctgtggatcagattgctgcaaatgtgaattttctcccaatggtgcctgta cataatattagatctccaacagttgaagaattgaaaacttatacttctcaagttgaggac ttaagccaagaagcaaatgttcttcacatacaggaaaacctgacaagtgaatcctcccta agtctagatagaaaaatatttgatctccttctgagtatcagtcaatgtttgagcattgtt gaagagatgctgcagatctctggcctctctagagaggatactgctgtccagcatgcccac tatgagatgctgtctctagaattgagaaaacttcactcagctataactaacaaaaaggat gatcttttgaaactgataagtcaccctgggaagagctccagtgtattctttgagtgcttt aataacctccaaacacgacttgagcaaactcaggctgcagctttttccagaagtcaatct atgaaatctggcatagaaaataatagtgattatcagagtcaagtaagggagttgtatgac caactaattgagaaaaagtcttcagtacagcattccttgaatgaaattagtagtcaaagt attgttgaacaactccagaaagcagatttatatgctataaaacttcaagattatgaagtc caggtagcaaaactgagagatgaaggggaaagactttacttgccttatgttttaatacaa gaagtgtacaaactggaggatgtccttgatgacatgtggggacttctaagagccaaacat gctgaactcaacagccctttcatcagtgaaagtcaacaggaaggattgcttaaaggattg acagaactagtgaatactggaaaagaaaagcttgatcagggtcaacaatggcaagccaaa agtaaagcttctttacaagctcagctacaaaaccacaagatttttttccagaagcttgtt 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atgaattacaaacagtggatcattgattttgtcaatcaatcactgctacagctaagcacc agtgatgtagaaagtaagcgctatgaaagaactgaatttgcagagcgccttggagaaatg aatcgtcagtggcataagttacatgggacactaaacagaaagattcaacatttagaacaa cttctggaatccatcactgagagtgaaaacaaaatacagactttgaggaattggatagaa gcccaaggagagagactaaaaacattacaaaaacctggaagtgtaatatcagcaaggaag actctgctggactgtcaggacctagaaaatcacttgacatctaaatctagaacactggat gaattaaaagaaaattacatggctttggaaagtggcccagtgccagtgttacaggacacc atttctggaattgctggtttatatcaaatgaggaacaacattgccaatcaggtcaaccaa ctcaaaacttccatgcagtcaatattacagcaaggaaagggttatgataaactctttgag gaagtgaacatgttgactatccgattctggtactgcttggagcacagcaagcctgctatg ttaactctggaagctttgagatgtcaagtgaagaaccttcagcttcttcaagatgaagca gagagcagtgaaggaaattggagcaaactccagaatgctattagtaaactcaaagactat tgtccttccgttactgagataattgaacagaagtatcaagaagcacatacaaggtggact ctagtgaatcatgaaattgcagatcagttgcaatcagcccaaagtatgttacagctttgg gagtcttacactattgcccatgctgaaggaacagctaaactagaacagcttgaagagaag tttaaacacattttgaacattaatatgtctggagacaacctgactgagaacctaattcag gccctaaagaatgcaaagaacttgcaccatgacctagagaatgtaaaagaaacctttctt cagaattcagcaaccattggcccaaaactggagcaagcaagtcctgtcaaggaagatgtt gtttccagtcaatcttcttcacttcagaggatttcttatctggaaaaaatgctgcttatg aagtcaaatgagtttgagcatgttctttcccaactgaaggacttcagggaccaattagaa tctttggaatgcagtgtcaaacatctgatagagaccttggacttacagggaagagaagac aatacagaatttttcctgaatcacatgttagaattaacagcactgtctcctgacatggaa catttgaatgaagtgagcttcaaactgccgcttagtgacatagatataaagacactacaa aatctgaatcgaaagtggactcaggcaactgccacagctctggagaagtgcagtgaactt cagggaactgaattcaatgaaaaattccttcacaaatttgaaaaatggatacagtttttg gagaagatagaagagtgtctgaaaatgaacttgactggtagacttgaggatcttctagag cagcagaaaacatttgagatgttgcaagctgagatttctgtaaatcagccaattgctgat tattttgtcacccagtcactccaacttctagatacaccagaaatagaaaagaggacggaa tttgttatgaaactcacgatgttgaaagagcggtggcaaggtgctacccgaagggctcag cagaggaagatcaccatcaatgagagggtgaaagaatggcgacacttcaatgcttctcta cagaatgtaacccacttccttattgatactgaccatttcctgtctgcagtcaagagcaga gagtcttacagtctttgccaaataagaagttttattcatgatctcaagaacaaagaagta cttcttcaaagacggcaaacaacctttgcacttaccttagatgcagggagaaagttactg acagtagctgatctagagaccaagaattccattgacagagaaatcagaaaattgcaagat ggctggaggaattgccaacttcaagtagccgaaatgactaaagaattccaaagcaccata gaaacctgggaccaatgtgaaaagcaaatcaaggagctggagagtcgactgcagacttta aaagcaaaaattaaagatcctctcccagaaccatacgaagagctctataaagaaaaggaa ctgattaaggaactggagaactccttggcaaactgggttcagaacttgaaggaacttaaa atcatgaaggctgacataacccggtacattcttgtggaagatgtgatggttttgaaggag caaatagatcatttgcacagacaatgggaggagctctgtttaagagtttcactgcgtaaa caagaaattgaggagagactcaattcctggattgtgttcaatgagaagaataaagactta tgtgcatggctggttcagatggaaaacaaagttctacaaacagcagacattagtattgaa gaaatgattgaaagattacagaaggactgtatggaagaaatcaacctctttagtgaaaat aaacttcatttgaagcaaatgggtgatcagttgataaaagccagcaataagaccagagtt gctgaaatagatgaaaagctcagcaaaattaatgatcgatggcaacatctatttgatgtc attggatccagggtgaagaagttgaaggagacctttgcttttatacagcaattagacaaa aacatgagcaaccttcgaagctggctggctcgaattgagtctgagctttctaaacctgtt gtttatgacatctgtgatgatcaagaaatccagaagagacttgctgaacagcaggaccta caacgggacattgaacagcatagtgcaggggtcgagtctgtatttaatatctgtgatgtc ctgttacatgactctgatgcttgtgctaatgagacagagtgtgattcaatacaacagaca accagaagcctagacagacggtggcgaaatatttgtgctatgtcaatggagcggcgaatg aagattgaagaaacatggagactctggcaaaagtttctggatgattattcccgctttgag gattggctgaagtcagctgagaagacagcagcctatccaaactcatccgaagtattatat acaagtgctaaggaagagctgaagaaatttgaggcttttcagtggcaaattcacgagaga ctcactcagttggagcttatcaataagcagtatagacgacttgctcgagagaaccgaaca gacactgccagcaaactgaagcagatggttcatgaaggcaatcagcgttgggacaacctc caaagacgagtcacagccattctacggagactcaagcattttaccaatcaaagggaagaa tttgaagggacccgggagagcatcctggtgtggctcacagaaatggacttgcagctgaca aatgtggagcatttctctgagagtgatgtggatgacaaaatgcgccagctccatggtttc caacaggaaattacattaaataccaacaagattgaccagctaattgtatttggagagcag ctgattcaaaagagtgagcctatggatgctgtattgattgaagatgagttagaagaactc caccggtactgtcaagaagtgtttggccgtgtggcccgatttcaccggcggttaacctct cacaatccaggattggaagatgaaaaagaagcctctgaaaatgaaacagatgtggaagat tcaagagaaatacaaagtgattcttggcataaaaaggaggtgaatgagggaccttcatcc cctcagtccctgtgtcatcttatgccacccccattgagtcatgaacggtcaggttgtgag accccagtcagtgtggactctatcccccttgaatgggatcacacaggtgatgtgggaggc tcctcctctcatgaagatgatgaagaaggaccatactacagtgccatgtcagatgtagaa atcactgaaaatcctgaggcatatcttaaaatgaccacaaaaactttgaaagcatcttct ggcaaatccatttctgatgctcatggatggcacactcccgacagccctactcaccaaaag catcactacaaaccaactgaagttgataggaatgaacctgaaacaagcaccccatataag ccagaatatgttaaacaacttatacctcctggaatggatagtgtggacagtggaagagaa ggacctgaaatgctaattgctagtgagcagaagggtcttacagatacagaacaagaagca ggtgtatttgatagttgggagctcattcaagcccaagatcttcgcaataaatttagaaca aaacaaaatttgcagcagtggcaacaactggattcagatatcaatgatgccaccctttgg ctgaaaggaacagaaaccgagctggaaaagcttgagatgatgaagcctgcagctgacatc caggaaaccgaatgcagagtgaaaagattcaaagatatactaaaagcctttgataactac aaagcattagtgatctccatcaacttgagcagcaagaaattccagcagccagatcacact gaatcaaaagaactccagaacagactccggcagctgaatttgctctgggaaaaagcaaat catttgttggacagctggagagagagcttgcggcattccctcatgcaatgccaggacttt catcagttgagtcagtccctcctattgtggctagcaagtgcagaaaatcggagatgtaag gcccaagtggatccaaatgcagatccccaaaccatcctggagagccagaaagagttgatg caactagaaaaggagttgttggagcagcagcttcaagtaaactctctccaggagatctca aagtacctacttgctaaaggagatggggaagattatattgaagctgatgaaaagattcat gtcattggaaagaaactcaaccagctgctggaccaagtttcacaagatttagaatctttt caggaaaaccaggatgaggatacgacattgacagctttggacgacgtggacagtaatggc catcatctgtcttcagattctgtgccaacttctcaagagaaggctggagcagagagaatt acagaagaaaagagtaagaaaaatagcagagtggaacatctttctgaccctgcctcaact ccgaccagctctgggccccgttccttcctctaccgggtgtttagagcagccctgcccctc cagttgtttttccttctcttgttgcttctggcttgcatgattccctcttcagaggaagac tacagttgcacccaagctaacaattttgcccgatctttctatcctatgctgaggtacacc aatggacccccaccaacatag

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