Methylomicrobium lacus: ACEPPP_01385
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Entry
ACEPPP_01385 CDS
T10917
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
mlau Methylomicrobium lacus
Pathway
mlau00230
Purine metabolism
mlau01100
Metabolic pathways
mlau01110
Biosynthesis of secondary metabolites
Module
mlau_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mlau00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ACEPPP_01385 (purL)
Enzymes [BR:
mlau01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
ACEPPP_01385 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
XGK39933
LinkDB
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Position
complement(307961..311842)
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AA seq
1293 aa
AA seq
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MLIIPGPVALSDFRITKLLADLKALEPQIQSVSARFVHFVDQQGDLENCEHSILKQLLDY
GSGPAEASDSDVRLLVVPRPGTISPWSSKATEIAQRCGLAAVNRIERGIEYTLQVATSLT
EATQRQLAALLHDRMTQSVCYGNTIPDLFSHHEPQPLQRVAIIEQGKPALLQANQTLGLA
LSDDEIDYLVSAFEGLGRNPTDVELMMFAQANSEHCRHKIFNANWTIDGVQEGRTLFGMI
RNTTQQHPDGILSAYSDNASVIEGFNNRVFRRDPVTGLYDYIEEDAHILMKVETHNHPTA
ISPHPGAATGSGGEIRDEGATGRGSTPKAGLTGFSVSHLKIPGFQQPWEEDHGKPSRIAS
ALDIMLEGPIGGAAFNNEFGRPNLAGYFRSYEQLAPGADKNSYRGYHKPIMIAGGLGSIR
PMLVNKQPIPAGSLIIILGGPAMLIGLGGGAASSLASGESSEDLDFASVQRENPEMQRRC
QEVINHCNALGEDSPIVSIHDIGAGGLSNAVPEIIHDCERGGRFELRQVNNADIGMSPMQ
IWCNEAQERYVVAIKPESLEQFQAFCEREHCLYAVIGVATQEEQLRLEDNLLGEAPVDLP
MSVLFGKPPRMHRDVQRQQAALQAVDLSGIEIGEAVKRVLSFPAVADKSFLIHIGDRSVT
GLVARDQMVGPWQVPVADVAVTASGFHARTGEAMAMGERTPLAVIDAPASGRMAIGEAIT
NIAAAPIAKISDIKLSANWMAAAGFPGEDAALFDTVEAVGMELCPALGIAIPVGKDSLSM
KTVWKDGDGEKTMTAPLSLIITAFAPVTDIERTLTPQLCCNHHGTVLILIDLGQGQNRLG
GSVLAQVYRQLGDTCPDLDDPSLLKAFFAAIQSLNAQGKLLAYHDRADGGLLSTVAEMIF
AGRLGAELILDNHGALLPALFNEELGAVIQVRASEADDVLAILKQAGLGDASRIIGRVVE
HQQLTVIHDGRVAYNATRADMQSQWSELSYRMQALRDNPDCAKQQFERIRDDNDPGLNVK
LTFDPNQDVAAPFIATSAKPKVAILREQGVNGHVEMAAAFDRAGFASIDVHMSDIISGRV
DLSVFKGLVACGGFSYGDVLGAGGGWAKSILFNPRARDQFEAFFNRQDTFGLGVCNGCQM
MSGLKEIIPGAELWPRFLRNRSEQFEARVALVEVQPSPSIFFSGMAGSRMPVAIAHGEGR
AEFATGHAKALAAQIVALSYVDNTGALTESFPANPNGSPLGITGLTTTDGRFTIMMPHPE
RCFRTVQNSWHPDDWNEYGAWMRIFRNARANVG
NT seq
3882 nt
NT seq
+upstream
nt +downstream
nt
atgttaattatcccaggtcctgttgcactttccgacttccgtatcaccaaactgctggcc
gatttaaaggcgcttgaaccgcagattcaatccgtgtcggcgcgcttcgtgcatttcgtc
gatcagcaaggcgatttggagaactgcgaacacagcattctgaagcaactgttggattac
ggttcaggccccgccgaagcgtccgactctgacgttcgtctgctggtcgtgccgcgcccc
ggcacgatctcgccgtggtccagcaaggcgaccgaaatcgcgcagcgctgcggccttgcc
gcggttaaccggatcgaacggggcatcgaatatactctgcaagtcgcgacgtccttgacc
gaggcgacacaacggcaattggcggccttgctgcatgaccggatgacgcagagcgtatgc
tacggcaacaccatcccagatttattcagccaccacgaaccgcagccactgcagcgcgtc
gcgatcatcgaacaggggaaaccggcattgctgcaagcgaatcagaccctgggcctggcc
ttgtcggacgatgaaatcgactatctggtgtccgctttcgaaggcctgggccggaatccg
accgatgtcgaactgatgatgtttgcgcaggcgaactccgagcattgccgtcacaagatc
ttcaatgcgaactggacgatcgacggtgtccaggaaggcaggaccctgttcggcatgatc
cgcaatacgacccagcaacatccggacggcatcctgtcggcctacagcgataacgcctcg
gtcatcgagggtttcaacaaccgagtcttccgccgcgatccagtgacaggtctttacgat
tatatcgaggaagacgcgcatatcctgatgaaggtcgaaacgcacaaccatccgaccgcg
atttcgccgcatccgggcgccgcgaccggctcaggcggcgagattcgcgacgaaggcgcg
accggccgtggctcgaccccgaaagccggcctgaccggtttttcggtgtcgcacctgaaa
attccgggctttcagcagccgtgggaagaagaccacggcaagccgtccaggatcgcgtcg
gcattggacatcatgctcgaaggcccgatcggcggtgccgccttcaacaacgaattcggc
cggccgaatctggccggctatttccgcagctacgaacaactggcgccgggcgcggataaa
aacagctatcgcggctatcacaagccgatcatgatcgccggcggcctgggctcgatccgg
ccgatgctggtcaacaagcagccgataccggcgggctcgctgatcatcatcctcgggggg
cccgcgatgctgatcgggctcggcggcggcgcggcttcgtcattggcctcaggcgaaagc
tccgaggacctcgatttcgcctcggtgcaacgcgaaaacccggaaatgcagcgccgctgt
caggaagtgatcaaccactgcaacgcgctgggcgaggattctccgatcgtctcgattcac
gacatcggcgcgggcgggctgtcgaacgcggtgcccgaaatcatccacgattgcgagcgc
ggcggccgtttcgaactgcgccaagtgaataacgcggacatcggcatgtcgccgatgcag
atctggtgcaacgaggcgcaggagcgctatgtggtcgcgatcaagcccgaatcgctggag
caatttcaggccttctgcgaacgcgagcattgcctgtatgcggtgatcggtgtcgcgacc
caggaagagcaactgcggctcgaagacaatctgctcggcgaggcgccggtcgatctgccg
atgtcggtcttgttcggcaagccgcccaggatgcaccgcgacgtgcagcggcagcaggcc
gctttgcaggcggtcgatctgagcggcatcgaaatcggtgaagccgtcaagcgtgtgctg
tctttcccggcggtcgcagacaaaagctttctgattcatatcggcgatcgttcggtgacc
ggtttagtcgcccgcgaccagatggtcggaccctggcaggtgccggtcgccgatgtcgcg
gttaccgcctccggctttcatgcccggaccggcgaggcgatggcgatgggcgagcggacg
ccgctggccgtgatcgatgcgccggcttccggccgcatggcgatcggggaggcgatcacg
aatatcgcggccgcgccgatcgctaagattagcgacatcaaactgtccgcgaactggatg
gccgcggccggttttccgggcgaagatgcggccttgttcgacacggtcgaggcggtcggc
atggagctgtgtcctgccttgggcatcgcgattccggtcggcaaggattcgttgtcgatg
aaaacggtgtggaaggacggtgacggcgaaaaaacgatgaccgcgccgttgtcgctgatc
attaccgcgtttgcgccggtcaccgacatcgagaggaccttgacgccgcagttgtgctgc
aatcatcatggcaccgtgttgatcttgatcgatctcggccaaggtcaaaaccgcctcggc
ggttcggtcctggcgcaggtttaccggcagctcggggacacgtgtccggaccttgacgat
ccgtctttattgaaagcgtttttcgcggcgattcaaagcctgaacgctcaaggcaagctc
ttggcctatcatgaccgcgccgacggcggcctcctgtccacggtcgcggaaatgatcttt
gccggccgtctgggtgccgaattgattctggataatcacggcgcgttgctgccggccttg
ttcaacgaagaattgggcgcggtgattcaggtcagagccagcgaagcggacgacgtgctc
gccatcctgaaacaggcaggtctgggcgatgcgagccgcatcatcggccgcgtcgtcgaa
caccaacaactgaccgtaatccatgacggccgcgtcgcgtataacgccacgcgcgccgac
atgcagtcgcagtggtccgagctcagctatagaatgcaggcgctgcgcgataacccggac
tgcgcgaaacaacagttcgaacgcattcgggacgacaacgatccggggctgaacgtgaag
ttgacattcgatccgaatcaggatgtcgccgcgcctttcatcgctacctcggcgaaaccg
aaagtcgcgatcctcagggagcagggcgtcaacggccatgtcgagatggcggccgcgttc
gaccgggccggcttcgcgagcatcgacgtgcacatgagcgacattatctcgggccgcgtc
gatttgtccgttttcaagggcctcgtcgcctgcggcggtttctcctacggcgacgtgctc
ggcgcgggcggcggctgggccaagtcgatcctgttcaatccccgcgcgcgcgatcaattc
gaagcgtttttcaaccggcaggatactttcggcctgggcgtctgcaacggctgccaaatg
atgtccggcttgaaggagatcatccccggcgccgaattgtggccgcgcttcctgcgcaac
cgttccgagcaattcgaggcacgggtcgccttggtcgaggtgcagccgtcgccgtcgatc
tttttcagcggcatggcggggtcgagaatgccggtcgcgatcgcgcacggcgaaggccgc
gccgaattcgcgaccggtcatgcgaaggcgctcgcggcgcaaatcgtcgccttgtcctat
gtcgacaacaccggcgccttgaccgaaagctttccggccaatccgaacggatccccgctc
ggcattaccggcctgaccaccacggatggccgcttcacgatcatgatgccgcatcccgaa
cgctgcttcagaacggtccaaaactcctggcatccggacgactggaacgaatacggcgcc
tggatgcggatattcaggaacgccagggccaatgtcggttaa
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