KEGG   Methylomicrobium lacus: ACEPPP_04680
Entry
ACEPPP_04680      CDS       T10917                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
mlau  Methylomicrobium lacus
Pathway
mlau00290  Valine, leucine and isoleucine biosynthesis
mlau00660  C5-Branched dibasic acid metabolism
mlau01100  Metabolic pathways
mlau01110  Biosynthesis of secondary metabolites
mlau01210  2-Oxocarboxylic acid metabolism
mlau01230  Biosynthesis of amino acids
Module
mlau_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
mlau_M00535  Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:mlau00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    ACEPPP_04680 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    ACEPPP_04680 (leuC)
Enzymes [BR:mlau01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     ACEPPP_04680 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     ACEPPP_04680 (leuC)
SSDB
Motif
Pfam: Aconitase
Other DBs
NCBI-ProteinID: XGK40555
LinkDB
Position
complement(1073017..1074438)
AA seq 473 aa
MPGKTLYDKLWEDHVVHTEDDGSSLIYIDRQLVHEVTSPQAFEGLRLSGRKPWRTDRNLA
VADHNVPTTDRAKGIADPVSRLQVETLEKNCAEFGITEFSMADERQGIVHVIGPEQGATL
PGMTIVCGDSHTSTHGASGALAFGIGTSEVEHVLATQCLVQKKAKNMLIRVNGKTGPGVT
AKDIVLAIIGKIGTAGGNGYTIEFAGDAIRALSMEGRMTICNMAIEAGARAGLIGVDETT
IEYYRGRPYAPKGNDWFMAERMWQNLHSDPDAVFDKTIDIDAASIRPQVTWGTSPELVVS
IDDKVPDPALETDATKKQSMIQALKYMDLKPGQAITDIKLDKIFIGSCTNSRIEDLRAAA
AVAKGKKVASSIKLAMVVPGSGLVKHQAEAEGLDKIFTEAGFEWRDPGCSMCLAMNADRL
EPGERCASTSNRNFEGRQGYGGRTHLVSPEMAAAAAIEGHFVDVSKWEKEVRQ
NT seq 1422 nt   +upstreamnt  +downstreamnt
atgccgggtaaaactttatatgacaaattatgggaagatcatgtcgtccataccgaggac
gacggttcttcattgatttatatcgaccgccaactggtgcacgaagtgacgtcgccgcag
gcgttcgaaggcctgcgcctgtcaggacgcaaaccgtggcgcaccgacagaaacctggcg
gtggccgaccataacgtgccgaccaccgaccgcgccaaaggcatcgccgatccggtttca
cgtttgcaggtcgagactctcgaaaagaactgcgccgaattcggcatcaccgaatttagc
atggcagatgagcgtcaaggcatcgtgcatgtgatcggccccgagcagggcgcgaccttg
ccgggcatgaccatcgtctgcggcgattcgcatacttcgacgcacggcgcctccggcgcg
ctggcgttcggcatcggcacctccgaggtcgagcatgtgctggcgacgcaatgcttggtg
cagaaaaaagccaaaaacatgctgatccgggtcaacggcaagaccggccccggcgtgacc
gcgaaagacatcgtgctggcgatcatcggcaagatcggcaccgccggcggcaacggctat
acgatcgaatttgccggcgatgcgatccgtgccttgtcgatggaaggccgcatgacgatt
tgcaacatggcgatcgaagccggcgcgcgcgcgggcctgatcggcgtcgacgaaaccacg
atcgagtattaccggggccggccttatgcgccgaaaggcaacgactggttcatggccgaa
cggatgtggcaaaacctgcattcggacccggatgcggtattcgacaagaccatcgatatc
gatgccgcttcgatccggccgcaggtgacctggggtacttcgccggaattggtggtttcg
atcgacgacaaggtgccggatccggcgctcgaaacggacgcgaccaagaagcaaagcatg
atccaggcgttgaaatacatggacctgaaaccgggccaggcgatcaccgacatcaagctc
gacaagattttcatcggctcctgcaccaattcccgaatcgaggatttgcgcgcggcagcg
gcggtcgcgaaaggcaagaaggtggcgtcgagcatcaagctggcgatggttgtgccgggc
tccggtctggtcaaacatcaggccgaggcggaaggcctggacaagatctttaccgaggcg
ggctttgaatggcgcgatcccggctgttcgatgtgtctggcgatgaacgcggaccggctg
gagccgggtgaacgctgcgcgtcgacctcgaaccgcaatttcgaaggccggcaaggctat
ggcggacgcacgcatctggtcagtccggagatggccgccgcggccgcgatcgaggggcat
tttgtcgatgtgagcaaatgggagaaggaggtacgtcaatga

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