KEGG   Mycobacterium leprae Br4923: MLBr00637
Entry
MLBr00637         CDS       T00842                                 
Symbol
uvrD2
Name
(GenBank) putative ATP-dependent DNA helicase
  KO
K03657  ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
Organism
mlb  Mycobacterium leprae Br4923
Pathway
mlb03420  Nucleotide excision repair
mlb03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:mlb00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03420 Nucleotide excision repair
    MLBr00637 (uvrD2)
   03430 Mismatch repair
    MLBr00637 (uvrD2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mlb03400]
    MLBr00637 (uvrD2)
Enzymes [BR:mlb01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.4  DNA 3'-5' helicase
     MLBr00637 (uvrD2)
DNA repair and recombination proteins [BR:mlb03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     MLBr00637 (uvrD2)
   MMR (mismatch excision repair)
    Other MMR factors
     MLBr00637 (uvrD2)
SSDB
Motif
Pfam: UvrD-helicase UvrD_C AAA_19 HRDC UvrD_C_2 AAA_30 Helicase_Sgs1 AAA_11
Other DBs
NCBI-ProteinID: CAR70731
UniProt: A0A0H3MUC0
LinkDB
Position
769127..771280
AA seq 717 aa
MDPMVMVVNPLTAGLDDEQREAVLAPRGPVCVLAGAGTGKTRTITHRIAHLVGAGHVATG
QVLAVTFTQRAAAEMRSRLRALGAAVQAVSDFGVVRVLTFHAAAHRQLRYFWPRVIGDTG
WQLLDSKFATVARAASSVRLHAGTDDVCDLAGEIEWAKASLIGPEEYVAAVAAIGRDTPL
DAAQIASVYAAYEALKARGNGVPGVTLLDFDDLLLHTAAAIENDAAVAEEFRDRYRCFVV
DEYQDVTPLQQRVLSAWLGDRDDLTVVGDANQTIYSFTGASPCFLLDFPRRFPDATVVRL
ERDYRSTPQVVSLANQVIAAAHGRVADSKFQLSGQREPGPAASFHEYSDEPAEAAAVAAS
IARLIEFGTSPSEIAVLYRVNAQSEAYEEALTEVGIAYQVRGGEGFFNRQEIKQALLALQ
RSAERSSQTEPNSPLSDVVRGVLEPLGLTAEKPVGSRARDRWEALTALAELADDEVAQHP
RLDLPGLLAELRLRADARHPPVVQGVTLASLHAVKGLEWDAVFLVGLADGTLPISRALAH
GAESEPVEEERRLLYVGITRARVYLALSWALSRTPGGRQSRKPSRFLNDIAPQMGQNPAS
SRSRRNRTATLRCRICKNDLTTPAAVMLQRCQICAADVDEELLLQLKAWRLSTAKEQNVP
AYVVLTDNTLIAIAELLPADEAALIAVPGMSVRKIEQYGSDVLQLVRCRAVAVRTQT
NT seq 2154 nt   +upstreamnt  +downstreamnt
atggatcctatggtaatggtcgtaaatccattgactgctggactggatgacgagcagcgc
gaggccgtgctggctccacgcggacctgtttgtgtgctcgcgggagccggaacgggtaaa
acccgcaccatcactcaccgcattgcccaccttgttggtgctggtcacgtcgccactggg
caggtgctggcggtgacattcacccagcgtgcagcggcggagatgcggtcccggttgagg
gcgcttggcgctgccgtacaagccgtttcggattttggcgttgtgcgagtcctgaccttt
catgctgccgcgcaccgccagttgcgatatttctggccacgggtgatcggtgacactggc
tggcagctgttggacagcaagtttgccaccgttgcgcgggcggctagtagtgtcaggctg
catgctggcactgatgacgtgtgtgacctcgccggcgagattgaatgggctaaggcctcg
ctgattgggcccgaagaatacgtggccgccgtggccgctatcggtagagacactccgctg
gacgccgcgcaaatcgcgagtgtctacgctgcctacgaagctcttaaggcccgcggcaat
ggcgtcccaggggtcacgctgctcgacttcgatgatctgctgctgcacaccgccgccgcg
atcgagaacgacgcagcggtagccgaggagttccgggaccgttaccgttgttttgtagtc
gatgagtaccaagacgtcaccccgctacagcaacgggtgctttcggcctggttgggtgat
cgagacgatctgactgtggtcggcgacgccaaccagaccatctactcgttcactggggct
tcaccttgtttcctgcttgacttcccccgacggtttcccgatgccacggtggtgcggctg
gagcgcgactaccggtctactccgcaggtggtgtcgcttgcaaatcaggtgatcgcagcg
gctcatggccgggttgcggacagcaaatttcagctgtccggccagcgtgagccgggtccg
gccgcgtcatttcacgagtattctgatgagcctgctgaggccgctgccgtggcagcatca
attgctcgactgatcgaattcggcacctcgccatccgagatcgcggtgctttaccgggtc
aatgcgcagtccgaggcgtacgaggaggcgttgaccgaggtggggattgcctatcaggtc
cgcggcggcgagggatttttcaaccgccaggagatcaaacaggcgctactagccctgcag
cgtagtgcggagcgcagctcccaaacagaaccgaacagcccattgtcggacgtggtccgc
ggtgttctggagccattggggctaacggctgagaaaccggtcggcagccgcgcccgggat
cgttgggaggcgctgaccgcattggccgaactggccgacgacgaagtggctcagcatccg
cggctggatcttccggggttgctggccgagctgcggttgcgggccgatgcccggcaccca
ccggtggtacagggcgtcacgttggcctcattgcatgccgttaaaggacttgagtgggat
gcggtgttcttagtcggattggccgacggaacactacccatctcgcgtgcgttggcgcat
ggtgctgaaagcgagcctgtcgaggaagagcgtaggctgctttatgttggaatcaccagg
gcccgagtgtatttggcacttagctgggcgttatcgcgaactccgggtggacgtcagagc
cgcaagccgtcgcggttcctcaacgacatcgcgccacagatgggtcaaaatcctgcgtcg
agcagatctcggcgtaatcggaccgctactttgcgctgccgtatttgcaaaaacgacctg
accacgcctgcggccgtcatgctgcagcggtgtcagatatgtgccgcagacgttgacgaa
gaattgttgctgcagctcaaagcgtggcggcttagcactgccaaggaacagaacgtgcct
gcttacgtcgttttaaccgataacacgttgattgcgattgctgagttgctgcccgccgat
gaggccgcgttgatcgctgtcccgggtatgagtgtacgcaaaattgagcaatacgggtcg
gacgtgctgcagttggttcgctgccgtgccgtcgcggttaggacgcagacctga

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