Mycobacterium leprae Br4923: MLBr02270
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Entry
MLBr02270 CDS
T00842
Symbol
menD
Name
(GenBank) putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase / 2-oxoglutarate decarboxylase
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
mlb
Mycobacterium leprae Br4923
Pathway
mlb00130
Ubiquinone and other terpenoid-quinone biosynthesis
mlb01100
Metabolic pathways
mlb01110
Biosynthesis of secondary metabolites
mlb01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mlb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
MLBr02270 (menD)
Enzymes [BR:
mlb01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
MLBr02270 (menD)
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Motif
Pfam:
TPP_enzyme_N
Motif
Other DBs
NCBI-ProteinID:
CAR72368
UniProt:
B8ZSY2
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Position
2693730..2695400
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AA seq
556 aa
AA seq
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MNPSTTQARVVVDELIRGGVRDVVLCPGSRNAPLAFALQDADHAGRIRLHVRIDERTAGY
LAIGLAVAAGAPVCVAMTSGTAVANLGPAVVEANYARVPLIVLSANRPYELLGTGANQTM
EQLGYFGTQVRAAISLGLAEDAPERLDSLNATWRSATCRVLVAATGSRTANAGPVQFDIP
LREPLIPDPEPHGAITPQGRPGGKPWTYIPQVTFDQPLEIDLSADTVVIAGHGAGVHPNL
TELPIVAEPTAPFGPYRPYPLHPLALPLLHPKQVIMLGRPTLHRPVSALLADPQVPVYAL
TTGPCWPDVSGNSQAAGTRAVTTGTPHPAWLQRCAEMNQHAISTVRSQLAAHPLITGLHV
AAAVADALRPGDQLVLGASNPVRDMALVGLSTDGIQVRSNRGVAGIDGTVSTAIGAALAY
ERSPGYAGSTDRPARTVALIGDLAFVHDSSGLLIGPTEPTPQQLKIVVSNDNGGGIFELL
EQGDPRLSAVSSRIFGTPHDVDVGALCRAYHVEGRQIEVDKLREALDEPGVGMRVLEVKA
DRSSLRQLHAAITATL
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgaacccctcgacgacacaggctcgcgtcgtcgttgacgagctgatccgcggcggcgtc
cgcgatgtagtgctgtgccccgggtcgcgaaacgccccgttggcattcgccctgcaagac
gccgaccacgccggccggatacggctgcacgtacgcattgacgagcgcaccgccgggtat
ctggctatcgggctggcggtcgccgcgggcgcgccggtgtgtgtggcgatgacctcgggc
actgccgtcgccaaccttggcccagcggtggtcgaagccaactatgcccgggtgccactg
atcgtgttatcggccaaccggccttatgaattgctcggcacaggggccaaccagaccatg
gagcagctgggctacttcggcacccaagttcgtgccgccatcagcctaggcctagcagag
gacgcgccggagcggctcgattcactcaacgcaacctggcgatcggccacctgccgagta
ttggtggctgccaccggttctcgtaccgccaacgccggccccgtgcagttcgacatccca
ctgcgcgagcctttaatacccgacccggaaccccacggcgccatcacaccgcagggccgg
cccggcggaaagccgtggacctacataccgcaggtgacgttcgaccagccgctggaaatc
gacttgtcagccgacaccgtcgtcatcgccgggcacggtgcaggcgtgcacccgaacctg
accgaattgccgatcgttgctgagccgaccgcgccatttggaccgtaccggccctacccg
ttgcaccccctagcgctgcctctgctgcacccgaagcaggtgatcatgctcggtcgcccg
acactgcaccgcccggtgtcggcgctactggccgacccacaagtgccggtgtacgcgctt
accactgggccgtgttggccggacgtctcgggcaattctcaggccgctggtactcgggcg
gtaaccaccgggacaccgcatccggcctggctgcagcgctgtgcggagatgaaccagcac
gcgatctcgacggtgcgcagccagctcgcggctcatccgttaatcacgggtttgcatgtc
gctgcagctgtggcagatgcactacggcccggtgaccaactggtgcttggggcgtccaac
ccggtgcgcgacatggcgttggttggtttgtccactgacggtattcaggtgcggtccaac
cgcggcgtcgctggcatcgacggcaccgtatccaccgcgatcggggcggcgctagcatat
gaacgatcccccggctacgctggtagcacagaccgcccggctcgtaccgtagcattaatc
ggagacctcgcattcgtccatgacagctcggggctgttgatcggccccaccgaacccaca
ccgcagcagctgaaaatcgtagtgtctaacgacaacggtgggggtatcttcgaactgctg
gagcaaggcgacccgaggttgtctgccgtatcgtcgcgcatcttcggtactccgcacgac
gtcgacgtaggagcgttgtgtcgcgcgtaccacgtggaaggtcgacagatcgaggtcgac
aagctgcgggaagccctcgacgaacccggtgttggcatgcgcgtgctggaagtcaaggcc
gaccgatcttcgctgcgccagttgcatgcagcaatcacggcaacattgtga
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