KEGG   Mycobacterium leprae TN: ML0153
Entry
ML0153            CDS       T00047                                 
Symbol
uvrD
Name
(GenBank) putative ATP-dependent DNA helicase
  KO
K03657  ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
Organism
mle  Mycobacterium leprae TN
Pathway
mle03420  Nucleotide excision repair
mle03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:mle00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03420 Nucleotide excision repair
    ML0153 (uvrD)
   03430 Mismatch repair
    ML0153 (uvrD)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mle03400]
    ML0153 (uvrD)
Enzymes [BR:mle01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.4  DNA 3'-5' helicase
     ML0153 (uvrD)
DNA repair and recombination proteins [BR:mle03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     ML0153 (uvrD)
   MMR (mismatch excision repair)
    Other MMR factors
     ML0153 (uvrD)
SSDB
Motif
Pfam: UvrD-helicase UvrD_C AAA_19 UvrD_C_2 PcrA_UvrD_tudor AAA_30 AAA_11 AAA_22 DEAD CarD_TRCF_RID ResIII
Other DBs
NCBI-ProteinID: CAC29661
Pasteur: ML0153
UniProt: Q9CD72 A0AAD0KPG0
LinkDB
Position
214272..216608
AA seq 778 aa
MSVHTTDAKPDSEVDRLLDGLNPQQRQAVVHEGSPLLIVAGAGSGKTTVLARRIAYLIAA
RSVGVSQILAITFTNKAAAEMRERVARLVGDHTGPSMWVSTFHSTCVRILRNQASLIGGL
NSNFSIYDVDDSRSLLQMIGQDMGLDIKRYSPRLMANAISNLKNELIDAESAVANLSSDT
DDLARTVATVYGEYQRRLRTANALDFDDLIGETVGILQAFPQIAEHYRRRFRHVLVDEYQ
DTNHAQYVLVRELVGHGARNSPDDMPPGELCVVGDADQSIYAFRGSTISNIEDFERDYPD
TTTILLEQNYRSTQNILSAANSVIARNFGRRDKRLWTDAGKGELIVGYVSDNEHDEAKFI
ADEIDALVGGGEITYDDVAVLYRANNLSRSLEEVFIPTGIPYKVVGGFCFYESKEIRDLI
AYLRVLDNPGDAVSMRRILNTPRRGIGDRAEACVSVYAENTGTSFADALQAVAEGKVPML
NTRSVKAIAGFVALLDDLRCRVDDDLGELVESVLERSGYLRELESSTDPQELARLDNLNE
LVSFAHEFSTEQANAAALAKSLHTPEDEDVPDTGALAAFLEKVSLMSDTDQIPENNSGVV
TLMTLHAAKGLEFPVVFVTGWEDGMLPHMRTLGDPTELSEERRLAYVGITRARQRLYLSR
AITRSSWGQPILNPESRFLREIPPELIDWRRSILTDSYSTPASGASRFGRVRPSSIRSGA
SKRALLVLAPGDRVTHDKYGLGRVEEVSGVGESAISLIDFGSSGRIKLMHNHAPVTKL
NT seq 2337 nt   +upstreamnt  +downstreamnt
atgagtgtgcacacgacagatgccaagcccgactctgaagtagatcggctgcttgacggc
cttaacccgcagcagcgccaggcggtggtacatgagggttcgccgctgctgattgtggcc
ggcgcgggctcgggcaaaactacagtattggctcgacggatcgcttacctgattgcagcc
cgaagtgtcggggtcagtcagattctggccatcaccttcaccaacaaagccgctgcggag
atgcgcgagcgcgtggcccgactggttggagaccacactgggccgtctatgtgggtgtcg
acgtttcattcgacctgcgtgcgcattctacgtaaccaggcttcgctgatcggcgggctc
aactccaacttttcgatctatgacgtcgatgattcgcgtagcctgctgcagatgatcgga
caagacatgggactcgacatcaagcggtattcgccacggctgatggccaacgccatctcc
aacttgaagaacgaattgatcgacgccgaaagtgcggtagccaacctgtcttcagacact
gatgacctggctcgcaccgttgccacagtctacggcgaataccagcggcgactgcggaca
gctaacgcgctggacttcgatgacctgatcggagaaactgttgggatcctacaagctttc
ccgcagatcgccgaacactaccggcggcggttccggcacgtcctagtcgacgaataccaa
gacactaaccacgcacagtacgtgctggtgcgggaattggtcggacacggggccaggaat
tcacctgacgacatgcctccgggggagttgtgcgttgtaggcgatgccgaccagtcgatc
tatgcgttccgcggatccaccattagcaatatcgaggacttcgagcgtgactacccggac
accacaacgattctgctggaacagaattaccgctcaacgcaaaacattctgtcggcggct
aactccgtgatcgctcgtaacttcggacgccgcgacaagcgcttgtggacagacgctggc
aaaggcgagttgatcgttggatacgtctccgacaacgagcacgacgaggccaagttcatc
gccgatgaaatcgatgctctggtcgggggtggcgagattacctacgatgatgtggctgtc
ttgtatcgagctaacaacttatcgcgatcattggaggaagtgtttatccccaccgggatt
ccgtacaaagttgttgggggtttttgtttttatgaaagcaaggagattcgcgaccttatc
gcttacctgcgagtactagataaccccggcgatgccgtcagtatgcggcgcatcctcaac
acaccgcgtcgaggcatcggcgatcgtgccgaggcttgtgtgtcggtgtacgcagaaaat
accggaactagcttcgccgatgcactacaggctgtggcggaaggcaaagtgcccatgcta
aatacccgctcggtgaaagcgatcgcggggtttgttgcactgcttgacgacctgcggtgt
cgtgtcgatgacgacctgggtgaactggtcgaatctgtgttggaacgcagcggatacctc
agggagttggagtcctccacggacccgcaggagttagcccgtctggacaacctcaatgaa
ctagtaagcttcgcacacgaatttagcactgaacaggctaacgctgccgcgcttgcgaag
tccttgcatactcccgaggatgaagacgtgccggataccggtgcgttggcggcgtttctg
gaaaaggtgtcactgatgtccgacaccgaccagatccccgagaacaattccggtgtcgtc
acactaatgacgttgcatgccgcgaaaggattggaatttcccgtggtgttcgtcactgga
tgggaggacggcatgttgccgcacatgcgaactctgggtgatccgaccgagctttcggag
gagcgtcggctggcctatgtcggcataacccgggcacgtcaacgtctctacttgagcagg
gccatcactcggtcttcttggggacagcccattctcaaccctgagtcacggttcctgcgg
gaaattcctccggaactcatcgactggcggcgtagtattctcaccgattcatacagtacg
ccagcgagtggcgcaagccggttcggtagggtgcgtccgtcgtcgatccggtccggggcg
agcaagcgtgcgctgctggtgctggcgcccggtgatcgagtgacgcacgacaagtacggc
ctgggtcgggttgaggaagtttccggggtcggtgaatcagcgatatcactgatcgacttc
ggcagttcggggcgaataaagctgatgcacaaccacgcccctgtcaccaagctttga

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