Mycobacterium leprae TN: ML0559
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Entry
ML0559 CDS
T00047
Symbol
ribA
Name
(GenBank) putative GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase
KO
K14652
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:
4.1.99.12
3.5.4.25
]
Organism
mle
Mycobacterium leprae TN
Pathway
mle00740
Riboflavin metabolism
mle00790
Folate biosynthesis
mle01100
Metabolic pathways
mle01110
Biosynthesis of secondary metabolites
mle01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mle00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00740 Riboflavin metabolism
ML0559 (ribA)
00790 Folate biosynthesis
ML0559 (ribA)
Enzymes [BR:
mle01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.25 GTP cyclohydrolase II
ML0559 (ribA)
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.12 3,4-dihydroxy-2-butanone-4-phosphate synthase
ML0559 (ribA)
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Gene cluster
GFIT
Motif
Pfam:
DHBP_synthase
GTP_cyclohydro2
NapD
fn3
Motif
Other DBs
NCBI-ProteinID:
CAC30067
Pasteur:
ML0559
UniProt:
Q9CCP4
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All DBs
Position
676302..677609
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AA seq
435 aa
AA seq
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MGPFDSKVAKMTRLDSVERAVADIAAGKAVVVIDDEDRENEGDLIFAAEKATLEMVAFMV
RYTSGYLCAPLDGAICDRLGLLPMFAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMR
LLADPASVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGAICEIVSQK
DEGSMAQTDELRVFADEHDLALITIADLIAWRRKHEKHIERVAEARIPTRHGEFRAIGYT
SIYDDVKHVALVRGEIAGSSGDGDDILVRVHSECLTGDVFGSRRCDCGTQLDAAMAMVAR
EGRGVVLYMRGHEGRGIGLMHKLQAYQLQDAGADTVDANIKLGFPSDARDYGIGAQILVD
LGVRSMRLLTNNPAKRVGLDGYGLQIIERVPLPVRANADNIRYLMTKRDKMGHDLGGLDD
FHESNYFPGEFGGAL
NT seq
1308 nt
NT seq
+upstream
nt +downstream
nt
gtgggcccttttgatagcaaggtggcaaagatgacgaggttggactccgtcgagcgggca
gttgccgacattgcggctggtaaagccgttgtcgtcatcgacgatgaggaccgcgagaac
gaaggcgacctgatcttcgccgccgaaaaggcaacgctggagatggtggcctttatggtc
cgctatacctcgggatacttgtgcgcgccactggatggtgcgatctgcgaccggttggga
cttttgccgatgtttgcggtgaatcaagacaaacatgggactgcctacacggtcactgtc
gatgcgagaaacggtgtaggaaccgggatttcggcttctgatcgggctaccacaatgcga
ttattagctgacccggctagtgtcgctgacgatttcacccgccccggccatgtggttccg
ttgcgtgccaaggacggcggtgtgttgcgccggccgggtcacacagaggccgccgtcgac
ttggcccggctggcaggattgcagcccgcaggagcgatctgcgagatcgtcagtcagaag
gacgaaggctcgatggcacagaccgacgagttgcgggtcttcgctgatgagcacgatctg
gcgctgatcaccattgccgatctgatcgcatggcggcgcaagcatgagaagcacatcgag
cgggttgctgaagcgcggatcccaacccgtcatggagagtttcgtgctattggctatact
agtatttacgacgacgttaagcatgtggcactggtccgcggcgaaattgccggatcaagc
ggtgacggcgatgacatattggtccgggtgcactccgagtgtttgacgggtgatgtgttc
ggctcacggcgttgcgattgtgggacccaactcgatgccgctatggctatggtggcgcga
gaaggacgcggtgtggtgttatacatgcgcggccatgaaggtcgaggtatcgggctgatg
cataaactgcaagcataccagctacaggatgctggcgcggacaccgtggacgctaacatc
aagcttggattcccttctgatgcaagggattacggaattggtgcgcagatactcgtcgat
ctcggagtgcgctcgatgcgactgttaaccaacaatcccgccaagcgggttgggctggac
gggtacggactgcagatcatcgagcgggtgccgcttccggtgcgggccaacgcggataac
atccgttacttgatgaccaagcgtgacaagatgggtcacgacctgggcgggttggatgat
tttcatgaatcaaactattttccaggtgaattcggcggtgctttatga
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