Mycobacterium leprae TN: ML1261
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Entry
ML1261 CDS
T00047
Symbol
hisA
Name
(GenBank) phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
KO
K24017
phosphoribosyl isomerase A [EC:
5.3.1.16
5.3.1.24
]
Organism
mle
Mycobacterium leprae TN
Pathway
mle00340
Histidine metabolism
mle00400
Phenylalanine, tyrosine and tryptophan biosynthesis
mle01100
Metabolic pathways
mle01110
Biosynthesis of secondary metabolites
mle01230
Biosynthesis of amino acids
Module
mle_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
mle00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
ML1261 (hisA)
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
ML1261 (hisA)
Enzymes [BR:
mle01000
]
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.1 Interconverting aldoses and ketoses, and related compounds
5.3.1.16 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
ML1261 (hisA)
5.3.1.24 phosphoribosylanthranilate isomerase
ML1261 (hisA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
His_biosynth
NMO
Dus
TMP-TENI
Sacchrp_dh_NADP
DUF6964
DeoC
Motif
Other DBs
NCBI-ProteinID:
CAC31642
Pasteur:
ML1261
UniProt:
Q9CC56
A0AAD0KUL3
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All DBs
Position
1506032..1506769
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AA seq
245 aa
AA seq
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MMSLILLPAVDVVEGRAVRLVQGKAGSENDYGSALDAALCWQRDGADWIHLVDLDAAFGR
GSNRELLSEMVGKLDVQVELSGGIRDDDSLNAALATGCARVNLGTAACENPHWCAQVIAE
HGDKIAVGLDVQIVDGQHRLRGRGWETDGGDLWDVLENLDRQGCSRFIVTDVTKDGTLDG
PNLDLLASVSDRTNVPVIASGGVSSLDDLRAIAKFTERGIEGAIVGKALYAERFTLPQAL
AVVRM
NT seq
738 nt
NT seq
+upstream
nt +downstream
nt
ttgatgtcgctgatacttttaccggctgtcgacgtggtcgaggggcgcgccgtgcgcctg
gttcaaggaaaggccggtagcgaaaacgattacggttcagcattggacgccgcgttgtgc
tggcaacgcgacggcgccgactggattcacctagtggatctggacgcagcgtttggtcgc
ggttccaaccgcgaactgctttctgagatggtgggcaagcttgatgtgcaggtcgagcta
tccggaggtattcgtgacgacgactctttgaatgctgcgctagctaccggctgtgcacgg
gtcaacctaggtacggccgcatgtgagaacccgcactggtgcgcacaggtgattgccgag
cacggtgacaagatcgccgtcggtttggacgtccagatcgtcgacggccagcatcggctg
cgtggacgcggctgggaaaccgacggaggagacctgtgggatgtgttagaaaatcttgat
agacaaggatgttcacggttcattgttaccgatgtcactaaggacggtacgttggacggt
cccaaccttgacctgctggcaagtgtctccgatcgcaccaacgtcccggtgatcgcgtcc
ggtggcgtttccagtctggatgacttgcgtgctatcgctaaattcaccgagcgcgggatc
gagggtgctattgtgggcaaagccctctatgccgaacggttcaccttgccgcaggcactg
gccgtggtgcggatgtag
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