KEGG   Mycobacterium leprae TN: ML1519
Entry
ML1519            CDS       T00047                                 
Symbol
thyA
Name
(GenBank) thymidylate synthase
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
mle  Mycobacterium leprae TN
Pathway
mle00240  Pyrimidine metabolism
mle00670  One carbon pool by folate
mle01100  Metabolic pathways
mle01232  Nucleotide metabolism
mle04981  Folate transport and metabolism
Module
mle_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mle00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    ML1519 (thyA)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    ML1519 (thyA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    ML1519 (thyA)
Enzymes [BR:mle01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     ML1519 (thyA)
SSDB
Motif
Pfam: Thymidylat_synt
Other DBs
NCBI-ProteinID: CAC30470
Pasteur: ML1519
UniProt: Q9CBW0 A0AAD0P817
LinkDB
Position
complement(1833026..1833826)
AA seq 266 aa
MLIATPYEDLLRLVLDCGVAKMDRTGTGTRSLFGQQLRYDLSVGFPLVTTKKVHFKSVVY
ELLWFLRGDSNVAWLHEHGVNIWDEWASSTGDLGPIYGVQWRSWPTSSGDYIDQISTALD
LLRTEPDSRRIIVSAWNVGEIPQMALPPCHAFFQFYVAQGRLSCQLYQRSADMFLGVPFN
IASYALLTHMMAAQSGLLVGEFVWTGGDCHIYDNHVEQVQLQLSREPRAYPELFLAQRDS
IFDYVYEDVVVTNYDPHPAIKAPVAI
NT seq 801 nt   +upstreamnt  +downstreamnt
gtgctgatagcgacgccatacgaggatttgctgcgtctcgtgcttgactgcggcgtagcc
aaaatggaccgcaccggcaccgggactcgcagtctgtttggtcagcagttgcgttacgac
ctgtcggttgggttcccgctagttacgacgaaaaaggtgcacttcaaatcggttgtctac
gagttgttgtggttcttgcgcggcgactccaacgtcgcctggttgcatgagcatggagtt
aatatctgggatgagtgggctagcagcacaggcgacctcgggccgatttatggtgtgcag
tggcgatcttggccgacctcttcgggtgattacatcgaccaaatcagcaccgcactggat
ttgctgcgtaccgaaccggattctcggcgcatcattgtgtcggcttggaatgtcggtgaa
atcccgcagatggcgctgccaccatgtcacgcgtttttccaattctacgtcgctcaaggc
cggctgagttgccagctgtaccagcgcagcgccgacatgttccttggtgtgccgttcaac
atcgccagttacgcgcttctgacccacatgatggccgcccagtccggtcttttggttggt
gagttcgtctggacgggcggtgattgccacatctacgacaaccatgtcgagcaggtacag
ctgcagctcagccgcgaaccccgagcatatccagaactctttttagcgcagcgtgattct
atcttcgactatgtctacgaggacgtcgtcgtcacgaattatgatccgcacccggcgatc
aaagccccagtcgcgatatga

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