Mycobacterium leprae TN: ML1942
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Entry
ML1942 CDS
T00047
Name
(GenBank) probable cholesterol dehydrogenase
KO
K16045
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
mle
Mycobacterium leprae TN
Pathway
mle00984
Steroid degradation
mle01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
mle00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00984 Steroid degradation
ML1942
Enzymes [BR:
mle01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
ML1942
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
ML1942
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_10
RmlD_sub_bind
NAD_binding_4
Polysacc_synt_2
NmrA
KR
adh_short
NAD_binding_2
Motif
Other DBs
NCBI-ProteinID:
CAC30897
Pasteur:
ML1942
UniProt:
Q9X785
Q7AQ16
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All DBs
Position
2327943..2329073
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AA seq
376 aa
AA seq
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MLRGVGNASLTTELGRVLVTGGSGFVGANLVTALLERGYQVRSFDRAPMPLPQHPQLEVL
QGDITDATVCTTAMDSIDTVFHTAAIIELMGGASVTDEYRQRSYTVNVGGTENLLRAGQK
SGVKRFVYTASNSVVMGGTPITGGDETMPYTKRFNDLYTETKVVAEKFVLSQNGVPDGET
MLTCSIRPSGIWGRGDQTMFRKAFESVVSGHVKVLIGSKNAKLDNSYVHNLVHGLILAAE
HLVPGGTAPGQAYFINDGEPINFFDFMGPIIKACGENWPRVRISGRLVRNVMAVWQRLHF
GFGLPKPPMEPLAVERVYLDNYFSIEKAHKELGYRPLFTTEQAMAECLPYYTELFEQIKV
AAKPHLASIAATPRPE
NT seq
1131 nt
NT seq
+upstream
nt +downstream
nt
atgcttcgcggcgtgggtaacgcatcgttgacgaccgagctcggacgcgtcttggtcacc
ggcggttcgggcttcgtcggcgctaatctggtgaccgccttgctggaacgcggataccag
gtacgctctttcgaccgcgccccgatgccgctgccgcagcacccgcagctggaggtgctg
caaggtgacatcaccgacgctacggtctgcactacagcgatggacagcatcgatacagtc
tttcacaccgcggcaatcatcgagctaatgggcggcgcttcggtgaccgacgagtatcgg
cagcgcagctacacggtcaacgtgggcggtaccgaaaacttgctccgcgcaggacaaaag
tccggagtcaaacggttcgtctacaccgcatccaacagtgtggtgatggggggcactccc
atcaccgggggtgatgaaacaatgccctataccaagcggttcaacgacctgtacaccgaa
accaaagtggtcgccgaaaaattcgtactctcacaaaacggcgtacccgatggtgaaacc
atgctaacatgttcgatcagacccagtggcatatggggtcgcggcgaccagacaatgttc
cgtaaggcattcgaaagtgtcgtatccggtcacgtcaaggtactcatcgggagtaagaac
gccaaactggataactcctacgtgcacaacctggtgcacggcttaatcttggctgccgag
cacctggtcccaggcggcaccgcacctggacaagcctacttcatcaacgatggcgagccg
atcaacttcttcgatttcatggggccaatcatcaaggcgtgtggtgaaaattggccacgg
gtgcggatctccggtcggctggtgcgcaacgtgatggctgtgtggcagcggctacacttc
ggcttcgggcttccgaagcctccgatggaaccgcttgcggtagaacgagtttacctcgac
aactacttttccatcgaaaaggcgcacaaagagctgggctatcggccgctgttcactacc
gaacaggccatggctgaatgtctaccttactacacagagttattcgaacaaatcaaggtg
gctgccaagccccatttggcatccatagccgccaccccgcggcccgagtag
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