KEGG   Mycobacterium leprae TN: ML1964
Entry
ML1964            CDS       T00047                                 
Symbol
rmlB
Name
(GenBank) dTDP-glucose 4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
mle  Mycobacterium leprae TN
Pathway
mle00521  Streptomycin biosynthesis
mle00523  Polyketide sugar unit biosynthesis
mle00525  Acarbose and validamycin biosynthesis
mle00541  Biosynthesis of various nucleotide sugars
mle01100  Metabolic pathways
mle01110  Biosynthesis of secondary metabolites
mle01250  Biosynthesis of nucleotide sugars
Module
mle_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:mle00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    ML1964 (rmlB)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    ML1964 (rmlB)
   01055 Biosynthesis of vancomycin group antibiotics
    ML1964 (rmlB)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    ML1964 (rmlB)
   00525 Acarbose and validamycin biosynthesis
    ML1964 (rmlB)
Enzymes [BR:mle01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     ML1964 (rmlB)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase RmlD_sub_bind 3Beta_HSD NAD_binding_4 Polysacc_synt_2 NAD_binding_10 Sacchrp_dh_NADP NmrA Ldh_1_N
Other DBs
NCBI-ProteinID: CAC30919
Pasteur: ML1964
UniProt: Q9CBH7
LinkDB
Position
2348333..2349334
AA seq 333 aa
MTMRLLVTGGAGFIGANFVHNAVRDHPDDTVTVLDAMTYAGRHESLADVDHAVRLVQGNI
TDTKLVFRLVAESDVVVHFAAETHVDNALDDPEPFLRTNVIGTFTILEAVRHHSVRLHHI
STDEVYGDLELDEPTRFTESTPYNPSSPYSATKAAGDMLVRAWVRSYGVRATISNCSNNY
GPYQHVEKFIPRQITNVLTGRRPKLYGTGVNVRDWIHVDDHNSAVWQILEKGQIGRTYLI
GAENGHNNLTVLRTLLQMMGRDPNDFDHVTDRVGHDLRYAIDPTPLYNELCWAPKHANFD
EGLRATIDWYRNNESWWRPLKDAVEARYEERGR
NT seq 1002 nt   +upstreamnt  +downstreamnt
ttgaccatgcggttattggtcaccggcggagcgggctttatcggagccaattttgtgcat
aacgcggtgcgcgaccatcccgacgatacggtgacggtgctagacgccatgacttacgca
ggcagacacgagtcgctggccgatgtcgaccatgctgtcaggctggtgcaaggcaatatc
accgacaccaagctggttttccgactggtcgccgagtccgacgtggttgtgcatttcgcc
gccgaaacccatgtggacaacgcgctcgacgacccagaaccgttcctacgcaccaacgtc
atcgggacgttcaccatcctggaggcagtgcgacaccacagtgtgcggctgcaccacatc
tcgaccgacgaagtctatggcgacctagagctcgacgaaccaacaaggtttactgagtca
acgccctacaacccgtcgagtccgtactcggcaaccaaagccgccggcgacatgttggtc
cgggcttgggtgcgctcctacggcgtgcgtgcgacgatttccaactgctccaacaactac
ggaccataccagcacgtcgaaaagttcattccgcgccaaatcaccaatgtgctcaccggc
cgccggcccaagttatacggcaccggcgtcaacgtccgcgactggatccacgtcgacgac
cacaacagcgccgtctggcaaatcctcgagaaaggccagataggccgcacttacctcatc
ggagccgaaaacgggcataacaacctgaccgtgttgcgcacactgctacagatgatgggc
cgagaccccaacgatttcgaccatgtcaccgaccgcgtcggccacgacttacggtacgcg
atcgacccaacaccgctgtacaacgaattatgctgggctccaaagcacgccaacttcgac
gagggattgcgcgccaccattgactggtatcggaacaacgaatcgtggtggagaccgttg
aaggacgccgtggaagcgcgctacgaagaacgaggtcggtga

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