Mycobacterium leprae TN: ML1964
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Entry
ML1964 CDS
T00047
Symbol
rmlB
Name
(GenBank) dTDP-glucose 4,6-dehydratase
KO
K01710
dTDP-glucose 4,6-dehydratase [EC:
4.2.1.46
]
Organism
mle
Mycobacterium leprae TN
Pathway
mle00521
Streptomycin biosynthesis
mle00523
Polyketide sugar unit biosynthesis
mle00525
Acarbose and validamycin biosynthesis
mle00541
Biosynthesis of various nucleotide sugars
mle01100
Metabolic pathways
mle01110
Biosynthesis of secondary metabolites
mle01250
Biosynthesis of nucleotide sugars
Module
mle_M00793
dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:
mle00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00541 Biosynthesis of various nucleotide sugars
ML1964 (rmlB)
09109 Metabolism of terpenoids and polyketides
00523 Polyketide sugar unit biosynthesis
ML1964 (rmlB)
01055 Biosynthesis of vancomycin group antibiotics
ML1964 (rmlB)
09110 Biosynthesis of other secondary metabolites
00521 Streptomycin biosynthesis
ML1964 (rmlB)
00525 Acarbose and validamycin biosynthesis
ML1964 (rmlB)
Enzymes [BR:
mle01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.46 dTDP-glucose 4,6-dehydratase
ML1964 (rmlB)
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Motif
Pfam:
GDP_Man_Dehyd
Epimerase
RmlD_sub_bind
3Beta_HSD
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
Sacchrp_dh_NADP
NmrA
Ldh_1_N
Motif
Other DBs
NCBI-ProteinID:
CAC30919
Pasteur:
ML1964
UniProt:
Q9CBH7
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All DBs
Position
2348333..2349334
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AA seq
333 aa
AA seq
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MTMRLLVTGGAGFIGANFVHNAVRDHPDDTVTVLDAMTYAGRHESLADVDHAVRLVQGNI
TDTKLVFRLVAESDVVVHFAAETHVDNALDDPEPFLRTNVIGTFTILEAVRHHSVRLHHI
STDEVYGDLELDEPTRFTESTPYNPSSPYSATKAAGDMLVRAWVRSYGVRATISNCSNNY
GPYQHVEKFIPRQITNVLTGRRPKLYGTGVNVRDWIHVDDHNSAVWQILEKGQIGRTYLI
GAENGHNNLTVLRTLLQMMGRDPNDFDHVTDRVGHDLRYAIDPTPLYNELCWAPKHANFD
EGLRATIDWYRNNESWWRPLKDAVEARYEERGR
NT seq
1002 nt
NT seq
+upstream
nt +downstream
nt
ttgaccatgcggttattggtcaccggcggagcgggctttatcggagccaattttgtgcat
aacgcggtgcgcgaccatcccgacgatacggtgacggtgctagacgccatgacttacgca
ggcagacacgagtcgctggccgatgtcgaccatgctgtcaggctggtgcaaggcaatatc
accgacaccaagctggttttccgactggtcgccgagtccgacgtggttgtgcatttcgcc
gccgaaacccatgtggacaacgcgctcgacgacccagaaccgttcctacgcaccaacgtc
atcgggacgttcaccatcctggaggcagtgcgacaccacagtgtgcggctgcaccacatc
tcgaccgacgaagtctatggcgacctagagctcgacgaaccaacaaggtttactgagtca
acgccctacaacccgtcgagtccgtactcggcaaccaaagccgccggcgacatgttggtc
cgggcttgggtgcgctcctacggcgtgcgtgcgacgatttccaactgctccaacaactac
ggaccataccagcacgtcgaaaagttcattccgcgccaaatcaccaatgtgctcaccggc
cgccggcccaagttatacggcaccggcgtcaacgtccgcgactggatccacgtcgacgac
cacaacagcgccgtctggcaaatcctcgagaaaggccagataggccgcacttacctcatc
ggagccgaaaacgggcataacaacctgaccgtgttgcgcacactgctacagatgatgggc
cgagaccccaacgatttcgaccatgtcaccgaccgcgtcggccacgacttacggtacgcg
atcgacccaacaccgctgtacaacgaattatgctgggctccaaagcacgccaacttcgac
gagggattgcgcgccaccattgactggtatcggaacaacgaatcgtggtggagaccgttg
aaggacgccgtggaagcgcgctacgaagaacgaggtcggtga
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