Mycobacterium leprae TN: ML2161
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Entry
ML2161 CDS
T00047
Symbol
fadB
Name
(GenBank) putative fatty oxidation complex alpha subunit
KO
K01782
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:
1.1.1.35
4.2.1.17
5.1.2.3
]
Organism
mle
Mycobacterium leprae TN
Pathway
mle00071
Fatty acid degradation
mle00280
Valine, leucine and isoleucine degradation
mle00310
Lysine degradation
mle00362
Benzoate degradation
mle00380
Tryptophan metabolism
mle00410
beta-Alanine metabolism
mle00640
Propanoate metabolism
mle00650
Butanoate metabolism
mle00907
Pinene, camphor and geraniol degradation
mle00930
Caprolactam degradation
mle01100
Metabolic pathways
mle01110
Biosynthesis of secondary metabolites
mle01120
Microbial metabolism in diverse environments
mle01200
Carbon metabolism
mle01212
Fatty acid metabolism
Brite
KEGG Orthology (KO) [BR:
mle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
ML2161 (fadB)
00650 Butanoate metabolism
ML2161 (fadB)
09103 Lipid metabolism
00071 Fatty acid degradation
ML2161 (fadB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
ML2161 (fadB)
00310 Lysine degradation
ML2161 (fadB)
00380 Tryptophan metabolism
ML2161 (fadB)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
ML2161 (fadB)
09109 Metabolism of terpenoids and polyketides
00907 Pinene, camphor and geraniol degradation
ML2161 (fadB)
09111 Xenobiotics biodegradation and metabolism
00362 Benzoate degradation
ML2161 (fadB)
00930 Caprolactam degradation
ML2161 (fadB)
Enzymes [BR:
mle01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
ML2161 (fadB)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.17 enoyl-CoA hydratase
ML2161 (fadB)
5. Isomerases
5.1 Racemases and epimerases
5.1.2 Acting on hydroxy acids and derivatives
5.1.2.3 3-hydroxybutyryl-CoA epimerase
ML2161 (fadB)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
3HCDH_N
ECH_1
ECH_2
3HCDH
NAD_binding_2
F420_oxidored
DAO
NAD_Gly3P_dh_N
2-Hacid_dh_C
Motif
Other DBs
NCBI-ProteinID:
CAC31116
Pasteur:
ML2161
UniProt:
A0AAD0KV92
Q9CBD8
LinkDB
All DBs
Position
complement(2569161..2571305)
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AA seq
714 aa
AA seq
DB search
MADTAIQWSKDADGIVTLTMNDPSRSANVMNEIYIESMGNAVDRIVAEKDSITGVVITSA
KRTFFAGGDLTAMINTGSEEAGQCFDTVETVKKQLRTLETLGKPVVAAINGAALGGGLEI
ALACHHRIAADVKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVNILSQGTRFKPAK
AKEIGLVDELLSTVEELVPAAKAWIKANPEAHEQPWDKKSYEMPGGTPTSPGLAAILPSF
PSLLRKQLKGAPMPAPRAILAAAVEGAQVDFDTASRIESRYFVSLVTGQVAKNMIQAFFL
DLQHINSGGSRPDGIGKTPIKKIGVLGAGMMGAGIAYVSAKAGYNVVLKDVSLEAAQKGK
SYSEKLEAKALERGRTTQEKSDVLLACIAPTGDPTDLKGVDFVIEAVFENQELKHKVFQE
IEDIVDPNAVLGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMPLVEIIKGEKTSDEA
LARVFDYALAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPSSIEQAGAQAGYP
APPLQLSDELNLELMHKIAIATRKGVEDAGGMYESHPAETVVEKMIKLGRSGRLKGAGFY
EYVDGKRSGLWLGLRETFKSGSSQPPLQDMIDRMLFAEALETQKCLDENVLTSTADANIG
SIMGIGFPPWTGGSAQFIAGYSGPAGTGQQAFVSRARELVAKYGDRFLPPESLL
NT seq
2145 nt
NT seq
+upstream
nt +downstream
nt
atggcagacactgcaattcagtggagtaaggacgccgacggtattgtcacgctgacaatg
aacgacccgtccaggtcggccaacgttatgaacgagatttacatcgaatcgatgggcaat
gcggtggatcgcattgttgcggaaaaagattcgattaccggtgtggttataaccagcgct
aaaaggactttctttgccggcggtgacctcaccgcgatgatcaatactggatcagaagag
gccgggcaatgcttcgacactgtcgagacggtcaagaaacaattgcgcaccctggaaacg
ctgggcaagccggtcgttgccgccatcaacggtgccgcgctgggcggcggtctggagatc
gcgctcgcatgtcatcaccggatcgctgccgacgtcaagggcagtcagctcggcttgcct
gaagtgacgctggggctgttgcccggcggcggtggggtgacccgcacggtgcggatgttt
ggcatccagaacgcgttcgtcaacattctgtcacagggcacccgctttaagcctgccaag
gctaaggagatcgggctggtcgacgagctgttgtcaacagtcgaggagctggtgcccgcg
gctaaggcgtggatcaaggccaacccggaagcgcacgagcagccgtgggacaagaagagc
tacgagatgcccggtggtactccgacctcgccagggttggcggccattctgccgtcattc
ccgtcgctgttacgcaagcagctcaagggcgcgccgatgccggccccgagggccatcttg
gccgccgcggtcgagggcgcgcaggtcgacttcgacaccgccagccgtattgagagccgc
tacttcgtttcgctggtcaccggccaggtcgccaagaacatgatccaagcgtttttctta
gatctgcagcacatcaattccggtgggtctcgacccgacggcattggtaaaaccccgatc
aagaagatcggtgtgctgggtgcgggtatgatgggcgccggtatagcctacgtctcggcc
aaggcgggctacaacgtggtgcttaaggatgtgagtcttgaggccgcgcagaagggcaag
agctactcggagaagctggaagccaaggcgctagagcggggccgcactacgcaggagaag
agcgacgttctgctggcgtgcatcgccccgacaggcgaccctactgatctcaagggcgtt
gacttcgtgatcgaagccgtcttcgagaaccaggaactcaagcacaaggtgttccaggag
atcgaagacatcgtcgaccccaatgcggtactcgggtcgaacacctcgacgttgccgatt
accggtctggcgaccggcgtcaagcggcaggaggactttatcgggatccacttcttctct
ccggtcgacaagatgccgctggtcgaaatcatcaagggcgagaagacctcggacgaggca
ctggcccgggtgttcgactacgccctggctattggcaagaccccgattgtggtcaacgac
agccgcggcttcttcacttcgcgggtgatcggcacttttgtcaacgaggcgctggcgatg
ctcggtgagggggtggaaccatccagcattgaacaggcaggtgcgcaggctggctacccg
gcgccgccgctgcagttgtccgacgagctgaatctggagctcatgcacaagatcgcgatc
gctacccgcaagggtgtcgaggatgccggcggcatgtatgagtcgcacccggcagaaacc
gtggtggagaagatgattaagctcggccggtccgggcgcttgaagggtgccggcttttac
gagtacgttgacggcaagcggtccgggttgtggctcggtctgcgggagacgttcaagtcg
ggctcgtcgcagccgccgttgcaggacatgatcgaccggatgctgttcgccgaggcgctg
gaaactcagaagtgcctcgatgagaacgtgctgacgtccactgccgacgccaatatcggg
tccatcatgggtatcggtttcccgccgtggaccggtggcagcgcgcagtttatcgccggc
tactctggcccggccggtaccggccagcaggccttcgtgtcccgagcccgtgagctggtg
gccaagtacggcgatcgctttctgccgccggagtcgctgctatag
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