Mycobacterium leprae TN: ML2205
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Entry
ML2205 CDS
T00047
Symbol
purM
Name
(GenBank) 5'-phosphoribosyl-5-aminoimidazole synthase
KO
K01933
phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.3.1
]
Organism
mle
Mycobacterium leprae TN
Pathway
mle00230
Purine metabolism
mle01100
Metabolic pathways
mle01110
Biosynthesis of secondary metabolites
Module
mle_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mle00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ML2205 (purM)
Enzymes [BR:
mle01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
ML2205 (purM)
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Motif
Pfam:
AIRS_C
AIRS
Motif
Other DBs
NCBI-ProteinID:
CAC31160
Pasteur:
ML2205
UniProt:
A0AAD0KVB3
Q9CBC2
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Position
complement(2619421..2620515)
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AA seq
364 aa
AA seq
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MMDPGKSPGGQLGNHGITYASTGVDIEAGDRSVELFKPMAVKAIRTEVLGGLGGFAGLFA
LRSGYREPVLAASTDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIA
VGRTVPERLSAIVDGIAEGCMLAGCALLGGETAEHPGLMEVDHYDIAATGVGVVEADDTL
GPDRVKPGDVIIALRSSGLHSNGYSLARSVLLEIDRMNLAGYVEEFGRTLGEELLEPTRI
YAKDCLALAAETHVRTFCHVTGGGLAGNLQRVIPHGLVAEVDRGTWTPAPVFAMIAQRGR
VAREEMEKTFNMGVGMIAVVAPEDTDRALAILTARHLDCWVLGTVCKGSKVGPRAKLVGQ
HPRF
NT seq
1095 nt
NT seq
+upstream
nt +downstream
nt
atgatggatcccggaaaaagccccggaggccagctgggcaatcatggcatcacctatgcg
tcgacaggggtggacattgaagccggtgaccgctcggtcgagttgttcaagccgatggca
gttaaggccatcagaaccgaggtgcttggaggtctaggaggattcgctgggttgttcgct
ctacgcagcggctaccgcgaaccggtgttagcggcttccaccgacggtgttggtaccaag
ctggcagtcgctcaggcgatggataagcacgacaccgttggcttggacctggtggcgatg
gtggtcgacgacctggtggtctgtggcgctgagccactgtttttgcaggactacattgct
gtcggccgaacggtgccggaacgactgagcgcgatcgtcgacggtattgccgaggggtgc
atgctcgcgggctgtgcgttactgggtggtgagaccgcagaacaccctggtctgatggaa
gtcgaccactacgacatcgcggcgaccggcgtcggtgttgtggaagccgacgataccctg
gggccagatcgtgtcaaacccggtgacgtaatcatcgcgctgaggtcttcgggtctccat
tccaacggatactcgctggctcgctcggtcctactcgagatcgatcggatgaacctggcc
ggttatgtggaggagttcggtcgcaccctgggcgaagagctattggagcccacccgcatc
tacgccaaggactgtctggcattggcggccgaaactcacgtccgtaccttctgtcacgtt
accggcggcgggctggccggcaatcttcaacgcgttatcccacacggattggtcgccgaa
gttgaccgcggcacgtggacacctgcaccggtgttcgccatgatagcccagcgtggcagg
gtcgcgcgtgaagagatggaaaagacgttcaacatgggcgtcggcatgatcgccgtggtc
gcgcctgaagatactgaccgtgctttggcgatattgaccgcacgtcacttggactgctgg
gtgctgggcactgtctgcaaaggcagcaaagtaggcccacgggcaaaactggtcggacaa
cacccgagattctaa
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