Mycobacterium leprae TN: ML2270
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Entry
ML2270 CDS
T00047
Symbol
menD
Name
(GenBank) putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase / 2-oxoglutarate decarboxylase
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
mle
Mycobacterium leprae TN
Pathway
mle00130
Ubiquinone and other terpenoid-quinone biosynthesis
mle01100
Metabolic pathways
mle01110
Biosynthesis of secondary metabolites
mle01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mle00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
ML2270 (menD)
Enzymes [BR:
mle01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
ML2270 (menD)
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Motif
Pfam:
TPP_enzyme_N
Motif
Other DBs
NCBI-ProteinID:
CAC31786
Pasteur:
ML2270
UniProt:
Q9CBB0
A0AAD0KTD2
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Position
2693805..2695475
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AA seq
556 aa
AA seq
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MNPSTTQARVVVDELIRGGVRDVVLCPGSRNAPLAFALQDADHAGRIRLHVRIDERTAGY
LAIGLAVAAGAPVCVAMTSGTAVANLGPAVVEANYARVPLIVLSANRPYELLGTGANQTM
EQLGYFGTQVRAAISLGLAEDAPERLDSLNATWRSATCRVLVAATGSRTANAGPVQFDIP
LREPLIPDPEPHGAITPQGRPGGKPWTYIPQVTFDQPLEIDLSADTVVIAGHGAGVHPNL
TELPIVAEPTAPFGPYRPYPLHPLALPLLHPKQVIMLGRPTLHRPVSALLADPQVPVYAL
TTGPCWPDVSGNSQAAGTRAVTTGTPHPAWLQRCAEMNQHAISTVRSQLAAHPLITGLHV
AAAVADALRPGDQLVLGASNPVRDMALVGLSTDGIQVRSNRGVAGIDGTVSTAIGAALAY
ERSPGYAGSTDRPARTVALIGDLAFVHDSSGLLIGPTEPTPQQLKIVVSNDNGGGIFELL
EQGDPRLSAVSSRIFGTPHDVDVGALCRAYHVEGRQIEVDKLREALDEPGVGMRVLEVKA
DRSSLRQLHAAITATL
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgaacccctcgacgacacaggctcgcgtcgtcgttgacgagctgatccgcggcggcgtc
cgcgatgtagtgctgtgccccgggtcgcgaaacgccccgttggcattcgccctgcaagac
gccgaccacgccggccggatacggctgcacgtacgcattgacgagcgcaccgccgggtat
ctggctatcgggctggcggtcgccgcgggcgcgccggtgtgtgtggcgatgacctcgggc
actgccgtcgccaaccttggcccagcggtggtcgaagccaactatgcccgggtgccactg
atcgtgttatcggccaaccggccttatgaattgctcggcacaggggccaaccagaccatg
gagcagctgggctacttcggcacccaagttcgtgccgccatcagcctaggcctagcagag
gacgcgccggagcggctcgattcactcaacgcaacctggcgatcggccacctgccgagta
ttggtggctgccaccggttctcgtaccgccaacgccggccccgtgcagttcgacatccca
ctgcgcgagcctttaatacccgacccggaaccccacggcgccatcacaccgcagggccgg
cccggcggaaagccgtggacctacataccgcaggtgacgttcgaccagccgctggaaatc
gacttgtcagccgacaccgtcgtcatcgccgggcacggtgcaggcgtgcacccgaacctg
accgaattgccgatcgttgctgagccgaccgcgccatttggaccgtaccggccctacccg
ttgcaccccctagcgctgcctctgctgcacccgaagcaggtgatcatgctcggtcgcccg
acactgcaccgcccggtgtcggcgctactggccgacccacaagtgccggtgtacgcgctt
accactgggccgtgttggccggacgtctcgggcaattctcaggccgctggtactcgggcg
gtaaccaccgggacaccgcatccggcctggctgcagcgctgtgcggagatgaaccagcac
gcgatctcgacggtgcgcagccagctcgcggctcatccgttaatcacgggtttgcatgtc
gctgcagctgtggcagatgcactacggcccggtgaccaactggtgcttggggcgtccaac
ccggtgcgcgacatggcgttggttggtttgtccactgacggtattcaggtgcggtccaac
cgcggcgtcgctggcatcgacggcaccgtatccaccgcgatcggggcggcgctagcatat
gaacgatcccccggctacgctggtagcacagaccgcccggctcgtaccgtagcattaatc
ggagacctcgcattcgtccatgacagctcggggctgttgatcggccccaccgaacccaca
ccgcagcagctgaaaatcgtagtgtctaacgacaacggtgggggtatcttcgaactgctg
gagcaaggcgacccgaggttgtctgccgtatcgtcgcgcatcttcggtactccgcacgac
gtcgacgtaggagcgttgtgtcgcgcgtaccacgtggaaggtcgacagatcgaggtcgac
aagctgcgggaagccctcgacgaacccggtgttggcatgcgcgtgctggaagtcaaggcc
gaccgatcttcgctgcgccagttgcatgcagcaatcacggcaacattgtga
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