Mycobacterium leprae TN: ML2608
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Entry
ML2608 CDS
T00047
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
mle
Mycobacterium leprae TN
Pathway
mle00290
Valine, leucine and isoleucine biosynthesis
mle00770
Pantothenate and CoA biosynthesis
mle01100
Metabolic pathways
mle01110
Biosynthesis of secondary metabolites
mle01210
2-Oxocarboxylic acid metabolism
mle01230
Biosynthesis of amino acids
Module
mle_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
mle_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
mle00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ML2608 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
ML2608 (ilvD)
Enzymes [BR:
mle01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
ML2608 (ilvD)
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
CAC32140
Pasteur:
ML2608
UniProt:
O06069
A0AAD0P8Y8
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Position
complement(3113024..3114718)
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AA seq
564 aa
AA seq
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MMPPDIKPRSRDVTDGLEKAAARGMLRAVGMNDDDFAKAQIGVASSWNEITPCNLSLDRL
AKAVKEGVFSAGGYPLEFGTISVSDGISMGHQGMHFSLVSREVIADSVETVMQAERLDGS
VLLAGCDKSLPGMLMAAARLDLASVFLYAGSILPGRTKLSDGTEHEVTLIDAFEAVGACS
RGLMPRADVDAIERAICPGEGACGGMYTANTMASAAEALGMSLPGSAAPPATDRRRDGFA
RRSGQAVIELLRRGITARDILTKEAFENAIAVVMAFGGSTNAILHLLAIAHEADVTLSLE
DFSRIGFKVPHIADVKPFGRHVMFDVDHIGGVPVVMKALLDAGLLHGDCLTVTGQTMAEN
LASIAPPDPDGQVIRTLHNPIHPTGGITILRGSLAPDGAVVKTAGLDSDVFEGTARVFDG
ERAALDALKDGTIAKGDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLLTDGRFS
GGTTGFCVGHIAPEAVEAGPIAFLRDGDRVLLDVVGCSLDVLVDPVEFSSRKKDFIPPAP
RYTTGVLAKYVKLVSSATVGAVCG
NT seq
1695 nt
NT seq
+upstream
nt +downstream
nt
atgatgccccctgacatcaaaccccgcagccgcgacgttaccgatggcctggagaaggcc
gctgctcgtggcatgttgcgcgcagtcggcatgaacgatgacgacttcgccaaggcgcag
atcggagttgcgtcatcatggaacgagatcacaccttgcaatctctcgctggaccgcctg
gccaaggcggtcaaggagggggtattctcggccggcggttatccgcttgagttcggaaca
atttcggtttccgacggcatctcgatggggcaccaggggatgcacttctcgctggtgtcg
cgcgaggttatagcggacagcgtcgaaaccgtaatgcaggccgagcgcctcgacggctca
gtgcttttggctggctgcgataaatcactacccggaatgctgatggccgccgcacgtctc
gacctcgcgtcggtatttctctacgccggctcgatcttgcccggacgaaccaagctctcc
gacggcaccgaacacgaagtcacgctcatcgacgcattcgaagcggtcggcgcgtgttct
cgcggattaatgccccgcgctgatgtcgacgccatcgagcgggcgatctgccccggcgag
ggggcatgcggtggcatgtacactgccaacactatggccagcgcagcagaggcgctgggt
atgtccttgccgggcagcgctgcgccgccggcaacagaccgtcgccgtgatggcttcgcg
cggcgtagcgggcaggccgtcatcgaactgctgcgtcgcggtataaccgctcgcgacatc
cttaccaaggaagcgtttgagaacgcgatcgcggtggtgatggcgttcggtggctcgacc
aacgcgatcctgcatctactggccattgcccatgaggccgacgtcaccttgtcgctcgag
gacttcagtcggatcggatttaaggtgccgcatatagccgacgttaagccgttcggccgg
cacgtgatgttcgacgtcgaccacatcggtggtgtgccggtggtaatgaaagcacttctg
gacgcaggtctactgcacggtgattgcctgacggtgaccggtcagacgatggccgagaac
ctagcctccattgccccgccagacccggatggccaggtgatccgcacgttgcataatcca
attcatccgacgggaggcattacgatcctgcgtggatcgttggcacctgatggcgcggtg
gttaagacggctggactcgactccgatgtgttcgaaggaactgcaagggttttcgacgga
gaacgggccgcgttggacgcactcaaggacggcaccatcgccaaaggcgatgttgtggtt
atccgctatgaaggcccgaaaggcggcccggggatgcgcgaaatgctagccatcaccggt
gccatcaaaggtgccgggctaggcaaagatgttctgctacttactgacggcaggttctct
ggcggaacgaccggcttttgcgtaggacacatcgcgccggaagctgtcgaagcgggacca
atcgcattcctgcgtgacggcgaccgggtcctgctagacgttgtcggctgctccctcgat
gtgctggtcgatccagtcgaattttcctctcggaaaaaggatttcattcctcctgcgcca
cgctacaccaccggtgtgcttgccaagtacgtcaagctcgtcagttcggcgacggtcggc
gcggtctgcggttag
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