Mandrillus leucophaeus (drill): 105527995 Help Entry 105527995         CDS       T08763                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu00220   Arginine biosynthesis mleu00330   Arginine and proline metabolism mleu01100   Metabolic pathways mleu04020   Calcium signaling pathway mleu04081   Hormone signaling mleu04145   Phagosome mleu04371   Apelin signaling pathway mleu04713   Circadian entrainment mleu04730   Long-term depression mleu04926   Relaxin signaling pathway mleu04970   Salivary secretion mleu05010   Alzheimer disease mleu05014   Amyotrophic lateral sclerosis mleu05022   Pathways of neurodegeneration - multiple diseases mleu05410   Hypertrophic cardiomyopathy mleu05412   Arrhythmogenic right ventricular cardiomyopathy mleu05414   Dilated cardiomyopathy mleu05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:mleu00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     105527995 (NOS1)    00330 Arginine and proline metabolism     105527995 (NOS1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     105527995 (NOS1)    04020 Calcium signaling pathway     105527995 (NOS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     105527995 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     105527995 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     105527995 (NOS1)   09154 Digestive system    04970 Salivary secretion     105527995 (NOS1)   09156 Nervous system    04730 Long-term depression     105527995 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     105527995 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     105527995 (NOS1)    05014 Amyotrophic lateral sclerosis     105527995 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     105527995 (NOS1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     105527995 (NOS1)    05412 Arrhythmogenic right ventricular cardiomyopathy     105527995 (NOS1)    05414 Dilated cardiomyopathy     105527995 (NOS1)    05416 Viral myocarditis     105527995 (NOS1) Enzymes [BR:mleu01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      105527995 (NOS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 Motif Other DBs NCBI-GeneID:  105527995 NCBI-ProteinID:  XP_011819934 Ensembl:  ENSMLEG00000030095 LinkDB All DBs Position Unknown AA seq 1438 aa AA seqDB search MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTQPLGPPTKAVDLSHQPSAGKEQPPAVDGASGPGNGPQHAQDDGQEAGSLPHANGLAP RPPGQDPAKKAARVGLQGRGENNELLKEIEPVLNLLTSGSRGVKGGTPAKAEMKDMGIQV DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPASGKQSPTKNGSPS KCPRFLKVKNWETDVVLTDTLHLNSTLETGCTEYICMGSIMLPSQHIRRPEDVRTKEQLF PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRC VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQPADWVWIVPPMSG SITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNGTPTKRRAIGFKKLAEAVKFSAKLM GQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKVMSMEEYDIVHLEHETLVLVV TSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKCPEPLRFFPRKGPPLPHGDTEVHGLA AARDSQHRSYKVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPH FCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIE KANNSLISNDRSWKRNKFRLTYVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRS TIFVRLHTNGNQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNT ALGVISNWTDEHRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATNEKEKQRLLVLSKG LQEYEEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLT VAIVSYRTRDGEGPIHHGVCSSWLNRIQADEVVPCFVRGAPSFHLPRNPQVPCILVGPGT GIAPFRSFWQQRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTA YSREPDKPKKYVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGK LSAEDAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS NT seq 4317 nt NT seq  +upstreamnt  +downstreamnt atggaggatcacatgtttggtgttcagcaaatccagcccaatgtcatttctgttcgtctt ttcaagcgcaaagttgggggcctgggattcctggtgaaggagcgggtcagtaagccacct gtgatcatctccgacctgattcgtgggggcgccgcggagcagagtggcctcatccaggcc ggagacatcattcttgcagtcaacggccggcccttggtggacctgagctatgacagcgcc ctggaggtactcagaggcattgcctccgagacccacgtggtcctcattctgaggggccct gaaggcttcaccacgcacctggagaccacctttacaggtgatgggacccccaaaaccatc cgggtgacacagcccctgggtccccccaccaaagctgtggatctgtcccaccagccatcg gccggcaaagaacaacccccggcagtggatggggcctcgggtcctgggaatgggcctcag catgcccaagacgatgggcaggaggctggctcgctcccccatgccaacggcctggccccc aggcccccaggccaggaccctgcaaagaaagcagccagagtcggcctccaaggcagaggg gagaacaatgaactgctcaaggagatagagcctgtgctgaaccttctcaccagtgggagc agaggggtcaagggagggacacctgccaaggcagagatgaaagatatgggaatccaggtg gacagagatttggacggcaaatcacacaaacctctgccccttggtgtggagaacgaccga gtcttcaatgacctatgggggaagggcaatgtgcccgtcgtcctcaacaacccatattca gagaaggagcagccccctgcctcaggaaaacagtcccccacaaagaatggcagcccctcc aagtgtccacgcttcctcaaagtcaagaactgggagactgacgtggttctcactgacacc ctccaccttaacagcacattggaaacgggatgcactgagtacatctgcatgggctccatc atgcttccttctcagcatatacggaggcctgaagatgtccgcacaaaagaacagctcttc cctctcgccaaagagtttattgatcaatactattcatcaattaaaagatttggctccaaa gcccacatggaaaggctggaagaggtgaacaaagagatcgaaaccactagcacctaccag ctcaaggatacagagctcatctacggagccaagcatgcctggcggaatgcctcgcgctgt gtgggcaggatccagtggtccaagctgcaggtattcgatgctcgcgactgcaccacagcc cacgggatgttcaactacatctgcaaccacgtcaagtatgccaccaacaaagggaacctc aggtctgccatcaccatattcccccagaggacagacggcaagcacgacttccgagtctgg aactcccagctcatccgctacgctggctacaagcagcccgacggctccaccctgggggac ccggccaacgtgcagttcacagagatttgcatacagcagggctggaaacccccgagaggc cgctttgatgtcctgccgctcctgcttcaggccaacggcaatgaccctgagctcttccag attcctccagagctggtgttggaagttcccatcaggcaccccaagtttgagtggttcaag gacctggggctgaagtggtacggcctccctgccgtgtccaacatgctcctggagattggc ggcctggagttcagcgcctgtcccttcagtggctggtacatgggcacagagattggtgtc cgcgactactgtgacaactcccgctacaatatcctggaggaagtggccaagaagatgaac ttagacatgaggaagacgtcctcactgtggaaggaccaggcgctggtggagatcaatatc gcggttctctatagcttccagcctgccgactgggtgtggattgtgccccccatgtctgga agcatcacccctgtgttccaccaggagatgctcaactaccggctcaccccctccttcgaa taccagcctgatccctggaacacccacgtctggaaaggcaccaacgggacccccacaaag cggcgagccatcggcttcaagaaactggcagaagctgtcaagttctcggccaagctgatg gggcaggctatggccaagagggtcaaagcaaccatcctgtatgccacggagacaggcaaa tcgcaagcttatgccaagaccttgtgtgagatcttcaaacacgcctttgatgccaaggtg atgtccatggaagaatatgacatcgtgcacctggaacatgaaactctggtcctcgtggtt accagcacctttggcaacggagatccccctgagaatggggagaaatttggctgtgcgttg atggaaatgaggcaccccaactctgtgcaggaagaaaggaagtgcccggaacccttgcgt ttctttccccgtaaagggcctcccctcccccatggtgacacagaagtccacggtctggct gcagcccgtgacagccagcacaggagctacaaggtccgattcaatagcgtctcctcctac tctgactcccaaaaatcatcaggcgatgggcccgacctcagagacaactttgagagtgct ggacccctggccaatgtgaggttctcagtgtttggtcttggctcacgagcataccctcac ttttgcgccttcggacatgctgtggacaccctcctggaagaactgggaggggagaggatc ctgaagatgagggaaggggatgagctctgtgggcaggaagaggctttcaggacctgggcc aagaaggtcttcaaggcagcctgtgatgtcttctgtgtgggagatgatgtcaacattgaa aaggcgaacaattccctcatcagcaatgaccgcagctggaagagaaacaagttccgcctc acctatgtggccgaagctccagaactcacgcaaggtctatccaatgtccacaaaaagcga gtctcagctgcccgactccttagccgtcaaaacctccagagccctaaatccagtcggtca actatcttcgtgcgtctccacaccaacgggaatcaggagctgcagtaccagcctggggac cacctgggcgtcttccctggcaaccacgaggacctcgtaaatgccctgatcgagcggctg gaagacgcaccccctgtcaaccagatggtgaaagtggaactgctggaggagcggaacacg gctttaggcgtcatcagtaactggacagacgagcaccgcctcccaccctgcaccatcttc caggccttcaagtactacctggacatcaccacgccaccaacgcccctgcagctgcagcag tttgcctccctagccaccaatgagaaggagaagcagcgtctgctggtcctcagcaagggt ttgcaggagtatgaggaatggaaatggggcaagaaccccaccatcgtggaggtgctggag gagttcccatccatccagatgccggccaccctgctcctgacccagctgtccctgctgcag ccccgctactattccatcagctcctccccagacatgtaccctgatgaagtgcacctcact gtggccatcgtttcctaccgcactcgagatggagaaggaccaattcaccacggcgtgtgc tcctcctggctcaaccggatacaggctgacgaagtggtcccctgtttcgtgagaggagca cccagcttccacctgccccggaacccccaagtcccctgcatcctcgttggaccgggcacc ggcattgcacctttccgaagcttctggcaacagcggcaatttgatatccaacacaaagga atgaacccctgccccatggtcctggtcttcgggtgccggcaatccaagatagatcatatc tacagggaagagaccctgcaggccaagaacaagggggtcttcagagagctgtacacggct tactcccgggagccagacaaaccaaagaagtacgtgcaggacatcctgcaggagcagctg gcggagtctgtgtaccgagccctgaaggagcaagggggccacatttacgtctgtggggac gtcaccatggccgctgatgtcctcaaagccatccaacgcatcatgacccagcaggggaag ctctcggcagaggacgccggcgtgttcatcagtcggatgagggatgacaaccggtaccac gaggatattttcggagtcaccctgcgaacgtatgaagtgaccaaccgccttagatctgag tccattgccttcattgaagagagcaaaaaagacaccgatgaggttttcagctcctaa

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