Mandrillus leucophaeus (drill): 105528264
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Entry
105528264 CDS
T08763
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu04270
Vascular smooth muscle contraction
mleu04360
Axon guidance
mleu04611
Platelet activation
mleu04625
C-type lectin receptor signaling pathway
mleu04810
Regulation of actin cytoskeleton
mleu05135
Yersinia infection
mleu05152
Tuberculosis
mleu05163
Human cytomegalovirus infection
mleu05200
Pathways in cancer
mleu05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
105528264 (ARHGEF12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
105528264 (ARHGEF12)
04625 C-type lectin receptor signaling pathway
105528264 (ARHGEF12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
105528264 (ARHGEF12)
09158 Development and regeneration
04360 Axon guidance
105528264 (ARHGEF12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105528264 (ARHGEF12)
05205 Proteoglycans in cancer
105528264 (ARHGEF12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
105528264 (ARHGEF12)
09171 Infectious disease: bacterial
05135 Yersinia infection
105528264 (ARHGEF12)
05152 Tuberculosis
105528264 (ARHGEF12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mleu04131
]
105528264 (ARHGEF12)
Membrane trafficking [BR:
mleu04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
105528264 (ARHGEF12)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PH_13
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
AAA_23
Motif
Other DBs
NCBI-GeneID:
105528264
NCBI-ProteinID:
XP_011820363
Ensembl:
ENSMLEG00000026495
UniProt:
A0A2K5XSW9
LinkDB
All DBs
Position
Unknown
AA seq
1544 aa
AA seq
DB search
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVVIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIRSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDGLGRTDCSSGDAS
RPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR
IFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKVRQSGLANEGTDAGY
LPTNSVSSVASGASFSQEGGKENDTGSKQVGETPAPGDTLDGTPRTLNTVFDFPPPPLDQ
VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIGKYTEWPTEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK
PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLEATLISSKPQSHSLSTS
GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQITIPDSHLPVSEERWALDALRNLGLLK
QLLVQQLGLTEKSAQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTG
DIATCYSPRTSTESSAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEH
FFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ
PMTGIPAMESTHQQQHSPQNTHSDGAVSPFTPEFLVQQRWGAMEDSCFEIQSPSSCADSQ
SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS
NT seq
4635 nt
NT seq
+upstream
nt +downstream
nt
atgagtggcacacagtctactatcaccgacaggtttcccctcaaaaaacctataaggcat
ggaagtattttgaaccgagagtcaccaacagataagaagcagaaagttgagcgcattgca
tcacatgattttgaccccacagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatatatggtcttgttcaacgttgcgtagtcatccagaaagatgacaat
ggatttgggctgacggtcagtggagacaatccagtcttcgtacagtctgtcaaagaagat
ggagcagccatgcgggctggagtacagacaggtgatcgaatcatcaaggtgaatggaacg
ctggtgactcattcaaatcatctggaggtggtgaagctaatcagatctggttcctatgta
gctctcactgttcagggacgcccacctgggtcgccccagattccacttgccgactctgaa
gtagagccatcagtcattggacatatgtctcccatcatgacatctcctcattcacctgga
gcatctgggaatatggagagaatcactagtcctgtgctcatgggggaggaaaacaatgtg
gttcataaccagaaagtagaaattctgagaaaaatgttacagaaagaacaggaacggcta
cagttattgcaggaagattacaaccgaacacctgcccaaagattgctaaaagagatccaa
gaggccaagaaacacattcctcagctgcaagagcagttatccaaagccacaggctctgct
caggatggagctgtagttacaccctccagacccttaggtgacaccctaacagtcagtgag
gcagaaacagatcctggagatggcttgggcaggactgactgtagcagtggagatgcttct
cggcccagtagtgacaatgcagatagtcccaagagtggccccaaagagaggatttatcta
gaggaaaacccagagaaaagtgaaacaattcaggacactgacactcaatcacttgtcgga
agtccctcaacccgtatagcacctcatattattggagcagaagatgatgattttggtact
gaacatgaacagatcaatggacagtgcagctgtttccagagcattgaattactaaaatct
cgcccggctcatttggctgttttcttacaccatgtagtttcacaatttgaccctgcaact
ttgctctgttatctctattcagacctgtataaacataccaattccaaggaaactcgtcgc
atcttccttgagtttcatcagttctttctagatcgatcagcacacctgaaagtttcggtt
cctgatgaaatgtctgcagatctagaaaagagaagacctgagctcattcctgaggatctg
catcgccactatatccaaactatgcaagaacgagtccatccagaggttcaaaggcactta
gaagattttcggcagaaacgtagtatgggactgaccttggctgaaagcgagctgactaaa
cttgatgcagagcgagacaaggaccggttgactttggagaaggagcggacatgtgcagaa
cagattgttgccaaaattgaagaagtattgatgactgctcaggctgtagaggaagataag
agttccaccatgcagtatgttattctcatgtatatgaagcatttgggagtaaaagtgaaa
gagcctcgaaatttggagcacaaacggggtcgtattggatttcttcccaaaatcaagcaa
agtatgaagaaagataaagaaggggaggaaaaagggaagcgaagaggattccccagcatc
ctgggacccccacggagaccaagccgtcatgacaacagtgcaattggcagagccatggaa
ctacagaaggcgcgccaccctaagcacttatccacaccctcatctgtgagtcctgaacct
caggactctgccaaggtgcgccagagtgggttagcaaatgaaggaacagacgctggatac
ctgcctaccaattccgtgtcttctgtggcttcaggggcctctttttcccaggaaggaggg
aaagagaatgatacaggatcaaagcaagttggagaaacaccagcacctggagacacctta
gatggcacacctcgtactctcaatactgtctttgatttcccaccacctccattagaccaa
gtgcaggaggaggaatgtgaagtagaaagggtgactgaacatgggacaccaaagcccttt
cgaaagtttgacagcgtagcttttggagaaagtcaaagtgaggatgaacaatttgaaaac
gacttagagacagatccacccaactggcagcagcttgttagtcgagaagtgttattggga
ctaaaaccttgtgagatcaaaagacaggaagtgattaatgaattgttctacactgaaaga
gctcatgttcgaacactgaaggttcttgatcaagtgttctatcagcgagtgtccagagaa
ggaattctgtcaccctcagagctacggaaaattttttcaaacttggaagatattcttcaa
cttcatattggattgaatgaacaaatgaaggctgttcgaaagagaaatgagacctctgtt
atcgatcagattggggaagatttgctgacatggttcagtggaccaggagaggagaaattg
aaacatgctgctgctaccttttgcagtaaccaacctttcgccctggaaatgatcaagtct
cgtcagaaaaaggattctcgatttcagacttttgtgcaagatgctgaaagtaatccactg
tgtcgtcgtcttcaactgaaggatattattcccactcaaatgcaaaggcttactaagtac
ccacttctattggataatattggcaaatacacagaatggccaacagaaagggagaaggtg
aagaaagctgcagatcactgtcgtcagatcttaaattatgtaaatcaggctgtcaaggag
gcagaaaacaagcagcgcctcgaagattatcagcgtcgccttgatacctccagcctgaag
ttgtcagagtacccaaatgttgaagagctcaggaatttggatttaacaaaaaggaagatg
attcatgaaggaccattggtttggaaggtgaatagagataaaactattgatttatacaca
ttgctgctggaagacattcttgtattgttacaaaagcaggatgatagactggtgttaagg
tgtcatagtaagattctggcatctacagctgatagcaaacatacgtttagccctgtcatt
aagttgagtacagtgttggttcgacaagtggcaacagataacaaagctttattcgtcatc
tccatgtcagacaatggagctcagatttatgaactggtggcacagacagtttctgaaaag
actgtctggcaggacctaatctgtcggatggctgcatcagtgaaggagcaatccacaaag
ccaattccattaccccagtcaacacctggcgaaggagataatgatgaagaagatccttca
aaattaaaagaggaacagcatggcatttcagtcactggtttgcagagtccagacagagat
ttgggattagaagctaccttaatatcatcaaaacctcagtctcattcactgagtacttct
gggaaatcagaggtacgtgatctctttgtggctgagagacagtttgcaaaggaacaacat
acagatgggacactaaaggaagttggagaagattatcaaatcacaatcccggattcacac
ctgcctgtctcagaagaacgatgggcattggatgcactaagaaatttgggtttgttgaag
cagttgctggtgcagcagctcggtttgactgagaagagcgctcaggaagactggcaacat
ttcccaagatataggacagcctctcaggggccgcagacagacagtgtcatccagaactct
gaaaatattaaggcctatcattctggtgaaggacatatgccctttagaactggaactggt
gacattgcaacttgttacagtcctcggacttcaactgaatcttccgctccacgggattca
gtgggactggcaccccaggatagccaggcaagtaacattttagtaatggaccacatgatt
atgaccccagagatgcctaccatggagccagaagggggtcttgatgacagtggagagcac
ttttttgatgcccgtgaagcacatagtgatgagaatccatcagaaggtgatggagcagtt
aacaaggaagagaaggatgttaatttacgcatctcaggaaactatttgatccttgatggc
tatgacccagtgcaggagagttccacagatgaggaggttgcgtcctcactgaccctgcag
cccatgacaggcatccctgctatggaatccacccaccagcagcaacattctcctcagaac
actcactctgatggggcagtttcaccattcacccctgaatttctggtccagcagcgctgg
ggagctatggaggattcctgttttgagatccagagtccctcctcttgtgcagattcgcag
agccagatcatggagtacattcataagatagaggctgaccttgaacacttaaagaaggtg
gaggaaagttacaccattctttgccaaaggctggctggatcagccctcacagacaagcac
tcagataaaagttag
DBGET
integrated database retrieval system
