Mandrillus leucophaeus (drill): 105529748 Help Entry 105529748         CDS       T08763                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu04072   Phospholipase D signaling pathway mleu04115   p53 signaling pathway mleu04140   Autophagy - animal mleu04150   mTOR signaling pathway mleu04151   PI3K-Akt signaling pathway mleu04152   AMPK signaling pathway mleu04211   Longevity regulating pathway mleu04218   Cellular senescence mleu04714   Thermogenesis mleu04910   Insulin signaling pathway mleu04919   Thyroid hormone signaling pathway mleu05163   Human cytomegalovirus infection mleu05165   Human papillomavirus infection mleu05168   Herpes simplex virus 1 infection mleu05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mleu00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     105529748 (TSC2)    04151 PI3K-Akt signaling pathway     105529748 (TSC2)    04152 AMPK signaling pathway     105529748 (TSC2)    04150 mTOR signaling pathway     105529748 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     105529748 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     105529748 (TSC2)    04218 Cellular senescence     105529748 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105529748 (TSC2)    04919 Thyroid hormone signaling pathway     105529748 (TSC2)   09149 Aging    04211 Longevity regulating pathway     105529748 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     105529748 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     105529748 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     105529748 (TSC2)    05163 Human cytomegalovirus infection     105529748 (TSC2)    05165 Human papillomavirus infection     105529748 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:mleu01009]     105529748 (TSC2) Protein phosphatases and associated proteins [BR:mleu01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      105529748 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  105529748 NCBI-ProteinID:  XP_011822360 Ensembl:  ENSMLEG00000038963 UniProt:  A0A2K5ZQW4 LinkDB All DBs Position Unknown AA seq 1807 aa AA seqDB search MAKPTSKDSGLKEKFRILFGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLSNRIRM IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIIQGQGERLGVLR ALFFKVIKDYPSNEDLHERLDVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVTWDI LLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKAS GPLSPPTGPPGPAPAGPAVRLGSLPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYL DKTKQREMVYCLEQGLIHRCASQCVVALSTCSVEMPDIMIKALPVLVVKLTHISATASMA VPLLEFLSTLARLPQLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDSLKSLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQSGPESSSSPGMNVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG ALDVPASQFPGSAASPGPQTAPAAKPEKASAGTRLPVQEKTNLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAST AKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVMEEGSPGEVPVPVEPPGLEDF EAALGVDRRTDAYSRSSSTSSQEEKSFHAEELVAGGIPIERAISSEGGRPSVELSFQPSQ PLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGILDGESAAWPASGEDSRGQ PEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGRRVERDAFKSRATASNAEKVPGINPSFV FLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELA ILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFH IATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYEC NLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKW IARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHTKGPAQTPAEPTPGYEMGQRKRLISSV EDFTEFV NT seq 5424 nt NT seq  +upstreamnt  +downstreamnt atggccaaaccaacaagcaaagattcaggcttgaaggagaagtttaggattctgtttgga ctgggaacaccgaggccaaatcccaggtctgcagaggggaaacagacggaattcatcatc accgcggaaatcctgagagagctgagtgtggaatgtggcctcagcaatcgcatccggatg atagggcagatttgtgaagtcgcaaaaaccaagaaatttgaagagcatgcagtggaagca ctctggaaggcggttgcggatctgttgcagccagaacggccgctggaggcccggcacgcg gtgctggctctgctgaaggccatcattcaggggcagggcgagcgtttgggggtcctcaga gccctcttctttaaggtcatcaaggattacccttccaacgaagacctccacgaaaggctg gacgtttttaaggccctcacagacaatgggagacacatcacttacttggaggaagagctg gcggactttgtcctgcagtggatggatgtcggcttgtcctcggaattccttctggtgctg gtgaacttggtcaaattcaacagctgttacctcgatgagtacatcgcaaggatggttcag atgatctgcctgctctgcgtccggaccgcgtcctctgtggacatagaggtctccctgcag gtgctggacgccgtggtctgctacaactgcctgccggctgagagcctcccgctgttcatc gtcaccctgtgccgcaccatcaatgtcaaggagctctgcgagccttgctggaagctgatg cggaacctccttggcacccacctgggccacagtgccatctacaacatgtgccacctcatg gaggacagagcctacatggaggacgcacccctgctgagaggagccgtgttttttgtgggc atggcactctggggagcccaccggctgtattctctcaggaactcgccgacatcggtgctg ccatcattttaccaggccatggcatgtccgaacgaggtggtgtcctatgagatcgtcctg tccatcaccaggctcatcaagaagtataggaaggagctccaggtggtgacgtgggacatt ctgctgaacatcatcgaacggctccttcagcagctccagaccttggacagcccggagctc aggaccatcgtccatgacctgctgaccacggtggaggagctgtgtgaccagaatgagttc cacgggtctcaggagagatactttgaactggtggagagatgtgcagaccagaggcctgag tcctccctcctgaacctgatctcctatagagcgcagtccattcacccggccaaggacggc tggattcagaacctgcaggcgctgatggagagattcttcaggagcgagtcccgaggcgcc gtgcgcatcaaggtgctggatgtgctgtcctttgtgctgctcatcaacaggcagttctac gaggaggagctgattaactcagtggtcatctctcagctctcccacatccctgaggataaa gaccatcaggtccgaaagctggccacccagttgctggtggacctggcagagggctgccac acacaccacttcaacagtctgctggacatcatcgagaaggtgatggcccgctccctctcc ccacccccggagttggaagaaagggatgtggccgcgtactcggcctccttggaggatgtg aagacagctgtcctggggcttctggtcatccttcagactaagctgtacaccctgcctgcg agccatgccacgcgcgtttatgagatgctggtcagccacattcagctccactataagcac agctacaccctgccaatcgccagcagcatccggctgcaggcctttgacttcctgttgctg ctgcgggccgactccctgcaccgcctcggcctgcccaacaaggatggggtcgtgcggttc agcccctactgcgtctgcgactacatggagccagagagaggctctgagaagaaggccagc ggccccctttctcctcccacagggccacctggtccggcgcctgcaggcccggctgtgcgg ctgggctccctgccctactccctgctcttccgcgtcctgctgcagtgcttgaagcaggag tctgactggaaggtgctgaagctggttctgggcaggctgccggagtccctgcgctacaaa gtactcatctttacctccccttgcagtgtggaccagctgtgctctgctctctgctccatg ctttcaggcccaaagacactggagcggctccgaggcgccccggaaggcttctccagaact gacctgcacctggctgtggttccagtgctgacagcattaatctcttaccataactacctg gacaaaaccaaacagcgcgagatggtctactgcctggagcagggcctcatccaccgctgt gccagccagtgcgtcgtagccttgtccacctgcagcgtggagatgcctgacatcatgatc aaggcgctgcccgtcctggtggtgaagctcacacacatctcggccacagccagcatggcc gtcccgctgctggagttcctgtccactctggccaggctgccgcagctctacaggaacttc gccgcggagcagtatgccagtgtgttcgccatctcgctgccgtacaccaacccctccaag tttaatcagtacatcgtgtgtctggcccatcacgtcatagccatgtggtttatcaggtgc cgcctgcccttccggaaggattttgtccctttcatcactaagggcctgcggtccaatgtc ctcttgtcttttgatgacacccccgagaaggacagcttcagggcccggagtactagtctc aacgagaggcccaagagtctgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtgaaagaattcaaggagagctctgcagccgaggccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggatacagacgtccctcaccagtgccagcctg gggtctgcagacgagaactccatggcccaggctgacgatagcctgaaaagcctccatctg gagctcacggaaacctgtctggacatgatggcccgatacgtcttctccaacttcacagct gtccccaagaggtctcctgtgggcgagttcctcctggcgggtggcaggaccaaaacctgg ctggttgggaacaagcttgtcactgtgacgacgagtgtgggaaccgggacccggtcgtta ctaggcctggactcgggggagctgcagtccggcccggagtcgagctccagccctggcatg aatgtgagacagacgaaggaggcgccagccaagctggagtcccaggctgggcagcaggtg tcccgtggggcccgggaccgggtccgttctatgtcagggggccatggtcttcgagttggc gccctggatgtgccggcctcccagttcccgggcagtgccgcttctccaggaccacagact gcaccagccgcgaagcctgagaaggcctcagccggcacccggcttcctgtgcaggagaag acgaacctggccgcctacgtgcccctgctgacccagggctgggcggagatcctggtccgg aggcccacagggaacaccagctggctgatgagcctggagaacccgctcagccctttctcc tcggacatcaacaacatgcccctgcaggagctgtccaacgccctcatggcagctgagcgc ttcaaggagcaccgggacacagccctgtacaagtcgctgtcggtgccagcggccagcacg gccaaaccccctcctctgcctcgctccaacacagtggcctctttctcctccctgtaccag tccagctgccaaggacagctgcacaggagcgtttcctgggcagactccgccgtggtcatg gaggagggaagtcctggcgaggttcctgtgccagtggagcccccaggattggaggacttt gaggcagcgctaggcgtggacaggcgcacagacgcctacagcaggtcgtcctcaacctcc agccaggaggagaagtcattccacgcagaggagctggttgccgggggaatccccattgaa cgagccatctcctcggagggtggccggccctctgtggagctctccttccagccctcacag cccctgagcaagtctagctcctctcctgagctgcagaccctgcaggacatcctcggggac cctggggacaaggccgacgtgggccggctgagccctgaggttaaggcccgttcacagtca gggatcctggacggggaaagtgctgcctggccagcctcgggcgaagacagtcggggccag cccgagggtcccttgccttccagctccccccgctcgcccagtggcctccggccccgcggt tacaccatctccgactcggccccatcacgcaggggcaggagggtagaaagggatgccttt aagagcagagccacagcttccaatgcagagaaagtgccaggcatcaaccccagtttcgtg ttcctgcagctctaccattcgcctttctttggcgacgagtcaaacaagccaatcctgctg cccaatgagtcacagtcctttgagcggtcggtgcagcttctcgaccagatcccatcatac gacacccacaagatcgccgtcctgtatgtgggagaaggccagagcaacagtgagctcgcc atcctgtccaacgagcatggctcctacaggtacacggagttcctgacgggcctgggccgg ctcatcgagctcaaggactgccagccagacaaggtgtacctgggaggcctggacgtgtgt ggtgaggacggccagttcacctactgctggcacgacgacatcatgcaagccgtcttccac atcgccaccctgatgcccaccaaggacgtggacaagcatcgttgcgacaagaagcgccac ctgggcaacgatttcgtgtccatcgtctacaatgactctggcgaggacttcaagctcggc accatcaagggccagttcaactttgtccacgtgatcatcaccccgctggactatgagtgc aacctggtgtccctgcagtgcaggaaagacatggagggccttgtggacaccagcgtggcc aagatcgtgtctgaccgcaacctgccttttgtggcccgtcagatggccctgcatgcaaac atggcctcacaggtgcaccacagccgctccaaccccaccgacatctacccctccaagtgg attgcccggctccgccacatcaagagactccgccagcggatctgcgaggaagccgcctat tccaaccccagcctgcctctggtgcaccccccatcccataccaaagggcctgcacagact ccagccgagcccacgcctggctacgagatgggccagcggaagcgcctcatctcctccgtg gaggacttcaccgagttcgtgtga

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