KEGG   Mandrillus leucophaeus (drill): 105530942
Entry
105530942         CDS       T08763                                 
Symbol
GSTM4
Name
(RefSeq) glutathione S-transferase Mu 4 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu00480  Glutathione metabolism
mleu00980  Metabolism of xenobiotics by cytochrome P450
mleu00982  Drug metabolism - cytochrome P450
mleu00983  Drug metabolism - other enzymes
mleu01100  Metabolic pathways
mleu01524  Platinum drug resistance
mleu05200  Pathways in cancer
mleu05204  Chemical carcinogenesis - DNA adducts
mleu05207  Chemical carcinogenesis - receptor activation
mleu05208  Chemical carcinogenesis - reactive oxygen species
mleu05225  Hepatocellular carcinoma
mleu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    105530942 (GSTM4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    105530942 (GSTM4)
   00982 Drug metabolism - cytochrome P450
    105530942 (GSTM4)
   00983 Drug metabolism - other enzymes
    105530942 (GSTM4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105530942 (GSTM4)
   05204 Chemical carcinogenesis - DNA adducts
    105530942 (GSTM4)
   05207 Chemical carcinogenesis - receptor activation
    105530942 (GSTM4)
   05208 Chemical carcinogenesis - reactive oxygen species
    105530942 (GSTM4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    105530942 (GSTM4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    105530942 (GSTM4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    105530942 (GSTM4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mleu02000]
    105530942 (GSTM4)
Enzymes [BR:mleu01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     105530942 (GSTM4)
Transporters [BR:mleu02000]
 Other transporters
  Pores ion channels [TC:1]
   105530942 (GSTM4)
SSDB
Motif
Pfam: GST_N GST_C GST_C_3 GST_C_6 GST_N_3 GST_N_2 GST_C_2 Bromo_TP GST_C_7
Other DBs
NCBI-GeneID: 105530942
NCBI-ProteinID: XP_011824078
Ensembl: ENSMLEG00000037767
LinkDB
Position
Unknown
AA seq 243 aa
MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
PYLIDGTHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
EKLKPEYLEGLPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPKCLDAFPN
LKDFISRFEVMPPSSFLFDAPCSFPSFEMLSQSWSYTKNNLHLLSAGFMPGTVPSTLYLL
CGI
NT seq 732 nt   +upstreamnt  +downstreamnt
atgtccatgacactggggtactgggacatccgcgggctggcccacgccatccgcctgctc
ctggaatacacagactcaagctatgaggaaaagaagtacacaatgggggacgctcctgac
tatgacagaagccagtggctgaatgaaaaattcaagctgggcctggactttcccaatctg
ccctacttgattgatgggactcacaagatcacccagagcaacgccatcctgcgctacatt
gcccgcaagcacaacctgtgtggggagacagaagaggagaagattcgtgtggacattttg
gagaaccaggctatggacgtctccaatcagctggccagagtctgctacagccctgatttt
gagaaactgaagccagaatacttggagggacttcctacaatgatgcagcacttctcacag
ttcctggggaagaggccatggtttgttggagacaagatcacctttgtagatttcctcgcc
tatgatgtccttgacctccaccgtatatttgagccgaagtgcttggacgccttcccaaat
ctgaaggacttcatctcccgctttgaggtgatgcccccatcctcctttctctttgatgcc
ccttgttcttttccctcctttgagatgctttcccagtcctggagctacacaaagaataac
ttgcatttattgagtgctggcttcatgccaggaactgtgcccagcacattatacctattg
tgtggaatttga

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