KEGG   Mandrillus leucophaeus (drill): 105535063
Entry
105535063         CDS       T08763                                 
Symbol
HDAC1
Name
(RefSeq) histone deacetylase 1 isoform X1
  KO
K06067  histone deacetylase 1/2 [EC:3.5.1.98]
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu03082  ATP-dependent chromatin remodeling
mleu03083  Polycomb repressive complex
mleu04110  Cell cycle
mleu04213  Longevity regulating pathway - multiple species
mleu04330  Notch signaling pathway
mleu04350  TGF-beta signaling pathway
mleu04613  Neutrophil extracellular trap formation
mleu04919  Thyroid hormone signaling pathway
mleu05016  Huntington disease
mleu05031  Amphetamine addiction
mleu05034  Alcoholism
mleu05165  Human papillomavirus infection
mleu05169  Epstein-Barr virus infection
mleu05200  Pathways in cancer
mleu05202  Transcriptional misregulation in cancer
mleu05203  Viral carcinogenesis
mleu05206  MicroRNAs in cancer
mleu05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    105535063 (HDAC1)
   03083 Polycomb repressive complex
    105535063 (HDAC1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    105535063 (HDAC1)
   04350 TGF-beta signaling pathway
    105535063 (HDAC1)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    105535063 (HDAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    105535063 (HDAC1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    105535063 (HDAC1)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    105535063 (HDAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105535063 (HDAC1)
   05202 Transcriptional misregulation in cancer
    105535063 (HDAC1)
   05206 MicroRNAs in cancer
    105535063 (HDAC1)
   05203 Viral carcinogenesis
    105535063 (HDAC1)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    105535063 (HDAC1)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    105535063 (HDAC1)
   05165 Human papillomavirus infection
    105535063 (HDAC1)
  09164 Neurodegenerative disease
   05016 Huntington disease
    105535063 (HDAC1)
  09165 Substance dependence
   05031 Amphetamine addiction
    105535063 (HDAC1)
   05034 Alcoholism
    105535063 (HDAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mleu03036]
    105535063 (HDAC1)
Enzymes [BR:mleu01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     105535063 (HDAC1)
Chromosome and associated proteins [BR:mleu03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class I HDACs
     105535063 (HDAC1)
   HDAC complexes
    Sin3A-HDAC complex
     105535063 (HDAC1)
    BRAF-HDAC complex
     105535063 (HDAC1)
    REST complex
     105535063 (HDAC1)
    SHIP complex
     105535063 (HDAC1)
    MiDAC complex
     105535063 (HDAC1)
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.6)
     105535063 (HDAC1)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    105535063 (HDAC1)
  Chromatin remodeling factors
   NuRD complex
    105535063 (HDAC1)
SSDB
Motif
Pfam: Hist_deacetyl
Other DBs
NCBI-GeneID: 105535063
NCBI-ProteinID: XP_011829439
Ensembl: ENSMLEG00000043256
UniProt: A0A2K6AEA9
LinkDB
Position
Unknown
AA seq 482 aa
MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAN
AEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAS
AVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHG
DGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI
FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGG
GGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLE
KIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEEDPDKRISICSSDKRIACEEEF
SDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKTEAKGVKEEVK
LA
NT seq 1449 nt   +upstreamnt  +downstreamnt
atggcgcagacgcagggcacccggaggaaagtctgttactactacgacggggatgttgga
aattactactacggacaaggccacccaatgaagcctcaccgaatccgcatgactcataat
ttgctgctcaactatggtctctaccgaaaaatggaaatctatcgccctcacaaagccaat
gctgaggagatgaccaagtaccatagtgacgactacattaaattcttgcgctccatccgt
ccagataacatgtcggagtacagcaagcagatgcagagattcaacgttggtgaggactgt
ccagtattcgacggcctgtttgagttctgtcagttgtctactggtggttctgtggcaagt
gctgtgaaacttaataagcagcagacggacatcgctgtgaattgggctgggggcctgcac
catgcaaagaagtctgaggcatctggcttctgttacgtcaatgacatcgtcttggccatc
ctggaactgctaaagtatcaccagagggtgctgtatattgacattgatattcaccatggc
gacggcgtggaagaggccttctataccacagaccgggtcatgactgtgtcctttcataag
tatggagagtacttcccaggaactggggacctgcgggatatcggggctggaaaaggcaag
tattatgctgttaactacccgctccgagacgggattgatgacgagtcctatgaggccatt
ttcaagccggtcatgtccaaagtaatggagatgttccaacctagcgcggtggtcttacag
tgtggctcagactccctgtctggggatcggttaggttgcttcaatctaaccatcaaaggg
cacgccaagtgtgtggaatttgtcaagagctttaacctgcctatgctgatgctgggaggt
ggtggttacaccattcgtaatgttgcccggtgctggacatacgagacagctgtagccctg
gatacggagatccctaatgagcttccatacaatgactactttgaatactttggaccggat
ttcaagctccacatcagtccttccaatatgactaaccagaacacgaatgagtacctggag
aagatcaaacagcggctgtttgagaaccttagaatgctgccgcatgcacctggggtccaa
atgcaggcgattcctgaggacgccatccctgaggagagtggcgatgaggacgaagaagac
cctgacaagcgcatctcgatctgctcctccgacaaacgaattgcctgtgaggaagagttc
tccgattctgaagaggagggagaggggggccgcaagaactcttccaacttcaaaaaagcc
aagagagtcaaaacagaggatgaaaaagagaaagacccagaggagaagaaagaagtcaca
gaagaggagaaaaccaaggaggaaaagacagaagccaaaggggtcaaggaggaggtcaag
ttggcctga

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