Mandrillus leucophaeus (drill): 105535644 Help Entry 105535644         CDS       T08763                                  Symbol TOP2B Name (RefSeq) DNA topoisomerase 2-beta   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:mleu00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     105535644 (TOP2B)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:mleu03032]     105535644 (TOP2B)    03036 Chromosome and associated proteins [BR:mleu03036]     105535644 (TOP2B) Enzymes [BR:mleu01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      105535644 (TOP2B) DNA replication proteins [BR:mleu03032]  Eukaryotic type   DNA Topoisomerases    105535644 (TOP2B) Chromosome and associated proteins [BR:mleu03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     105535644 (TOP2B)   Centrosome formation proteins    Centriole proteins     105535644 (TOP2B) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT Toprim HATPase_c DUF7180 Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  105535644 NCBI-ProteinID:  XP_011830200 Ensembl:  ENSMLEG00000034275 LinkDB All DBs Position Unknown AA seq 1545 aa AA seqDB search MWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWN NGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE TACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLDKDIVALMT RRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVC LTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHI WVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQ TQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDR YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKK HIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDD RKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVD GFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNN INLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQ ELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEY HTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILK EFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQR GYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEE LIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMSGKAIKGKVG KPKVKKLQLEETMPSPYGRRVIPEITAMKADASKKLLKKKKGDLDTTAVKVEFDEEFSGV PVEGAGEEALIPSAPINKGPKPKREKKEPGTRVRKTPTSSGKPGAKKVKKRNPWSDDESK SESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDDNNDLEELKVKASP ITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPSYSQKSEDDS AKFDSNEEDSASVFSPSFGLKQIDKVPSKTVAAKKGKPSSDTAPKPKRAPKQKKVVEAVN SDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTASKKPKKTSFDQDS DVDIFPSDFPSEPPSLPRTGRARKEVKYFAESDEEEEDVDFAMFN NT seq 4638 nt NT seq  +upstreamnt  +downstreamnt atgtgggtgtatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggt ttatacaagatctttgatgaaattttggttaatgctgctgacaataaacagagggataag aacatgacttgtattaaagtttctattgatcctgaatctaacattataagcatttggaat aatggaaaaggcattccagtagtagaacacaaggtagagaaagtttatgttcctgcttta atttttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagttacaggt ggtcgtaatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaa acagcttgcaaagaatacaaacacagttttaagcagacatggatgaataatatgatgaag acttctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattccaa ccagatctgtccaaatttaagatggaaaaacttgacaaggatattgtggccctcatgacc agaagggcatatgatttggctggttcatgtaaaggggtcaaggtcatgtttaatggaaag aaattgcctgtaaatggatttcgcagttatgtagatctttatgtgaaagacaaattggat gaaactggggtggccctgaaagttattcatgagcttgcaaatgaaagatgggatgtttgt ctcacattgagtgaaaaaggattccagcagatcagctttgtaaatagtattgcgactaca aaaggtggacggcacgtggattatgtggtagatcaagttgttggtaaactgattgaagtg gttaagaaaaagaacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccatata tgggtttttattaattgccttattgaaaatccaacttttgattctcagactaaggaaaac atgactctgcagcccaaaagttttgggtctaaatgccagctgtcagaaaaattttttaaa gcagcctctaattgtggcattgtagaaagtatcctcaactgggtgaaatttaaagctcag actcagctgaataagaagtgttcatcagtaaaatacagtaaaatcaaaggtattcccaaa ctggatgacgctaatgatgctggtggcaaacattccctggagtgtacactgatattaaca gagggagactctgccaaatcactggctgtgtctggattaggtgtgattggacgagacaga tacggagtttttccactcaggggcaaaattcttaacgtacgagaagcttctcataaacag atcatggaaaatgctgaaataaataatattattaaaatagttggtctacaatataagaaa agttacgatgatgcagaatctctgaaaaccttacgctatggaaagattatgattatgacc gatcaggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcacaat tggccatcacttttgaagcatggttttcttgaagagttcattactcctattgtaaaggca agcaaaaataagcaggaactttccttctacagtattcctgaatttgatgagtggaaaaaa catatagaaaatcagaaagcctggaaaatcaagtactataaaggattgggtactagtaca gctaaagaagcaaaggaatattttgctgatatggaaaggcatcgcatcttgtttagatac gctggtcctgaagatgatgctgccattaccttggcattcagtaagaagaagattgatgac agaaaagaatggttaacaaattttatggaagaccggagacagcgtaggctacatggctta ccagagcaatttttatatggtactgcaacaaagcatttgacttataatgatttcatcaac aaggaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgttgat ggctttaaacctggccagcggaaagttttatttacctgtttcaagaggaatgataaacgt gaagtaaaagttgcccagttggctggatccgttgctgagatgtcggcttatcatcatgga gaacaagcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaacaac attaacttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgct gcaagccctcgttatattttcacaatgttaagctctttagcaaggctactttttcctgcc gtggatgacaacctgcttaagttcctttatgatgataatcaacgtgtagagcctgagtgg tatattcccataattcccatggttttaataaatggtgctgagggcattggtactggatgg gcttgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgcta gatggcttggatcctcatcccatgcttccaaactacaaaaactttaaagggacgattcaa gaacttggtcaaaaccagtatgcagtcagtggtgaaatatttgtagtggacagaaacaca gtagaaattacagagcttccagttagaacttggacacaggtatacaaagaacaggtttta gaacctatgctaaatggaacagataaaacaccagcattaatttctgattataaagagtat catactgacacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagca gaagctgctggactgcataaagtttttaaacttcaaactactcttacttgtaattccatg gtactctttgatcatatgggatgtctgaagaaatatgaaactgtgcaagacattctgaaa gaattctttgatttacgattaagttattatggtttacgtaaggagtggcttgtgggaatg ctgggagcagaatctacaaagcttaacaatcaagcccgtttcattttagagaagatacaa gggaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagaga ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagag gatgaaacacaaaaccagcatgatgatagttcctccgattcaggaactccttcaggccca gattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaa ctgattaaacagagagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctcct tcagatctttggaaagaagatttagcagcgtttgttgaagaactggataaagtggaagct caagaacgagaagatattctggctggaatgtctggaaaagcaattaaaggtaaagttggc aaacctaaggtgaagaaactccaattggaagagacaatgccctcaccttatggcagaaga gtaattcctgaaattacagctatgaaggcagatgctagcaaaaagttgctgaagaagaag aagggtgatcttgatactacagcagtaaaagtggaatttgatgaagaattcagtggagtg ccagtagaaggtgcaggagaagaggcattgattccgtcagctcctataaataaaggcccc aaacccaaaagggagaagaaggagcctggtaccagagtgagaaaaacaccaacatcatct ggtaaacctggtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaag tcagaaagtgacttggaagaaacagaacctgtggttattccaagagattctttgcttagg agagcagccgccgaaagacctaaatacacatttgatttctcagaagaagaggatgatgat gctgatgatgatgatgatgacaataatgatttagaggaattgaaagttaaagcatctccc ataacaaatgatggggaagatgaatttgttccttcagatgggttagataaagatgaatat acattttcaccaggcaaatcaaaagccactccagaaaaatctttgcatgacaaaaaaagt caggattttggaaatctcttttcatttccttcatattctcagaagtcagaagatgattca gctaaatttgacagtaatgaagaagattctgcttctgttttttcaccatcatttggtctg aaacagatagataaagttccaagtaaaacagtagctgctaaaaagggaaaaccgtcttca gatacagcccctaagcccaagagagcccccaaacagaagaaagtagtagaggctgtaaac tctgactcagattcagaatttggcattccaaagaagactacaacaccaaaaggtaaaggc cgaggggcaaagaaaaggaaagcatctggctctgaaaatgaaggcgactataaccctggc aggaaaacatccaaaacagcaagcaagaaaccgaagaaaacatcctttgatcaggattca gatgtggacatcttcccctcagacttcccttctgagccaccttctctgccacgaaccggt cgggctaggaaagaagtaaaatattttgcagagtctgatgaagaagaagaagatgttgat tttgcaatgtttaattaa

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