Mandrillus leucophaeus (drill): 105539968 Help Entry 105539968         CDS       T08763                                  Symbol PLD2 Name (RefSeq) phospholipase D2 isoform X1   KO K01115   phospholipase D1/2 [EC:3.1.4.4] Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu00564   Glycerophospholipid metabolism mleu00565   Ether lipid metabolism mleu01100   Metabolic pathways mleu04014   Ras signaling pathway mleu04024   cAMP signaling pathway mleu04071   Sphingolipid signaling pathway mleu04072   Phospholipase D signaling pathway mleu04144   Endocytosis mleu04666   Fc gamma R-mediated phagocytosis mleu04724   Glutamatergic synapse mleu04912   GnRH signaling pathway mleu04928   Parathyroid hormone synthesis, secretion and action mleu05200   Pathways in cancer mleu05208   Chemical carcinogenesis - reactive oxygen species mleu05212   Pancreatic cancer mleu05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mleu00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     105539968 (PLD2)    00565 Ether lipid metabolism     105539968 (PLD2)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     105539968 (PLD2)    04072 Phospholipase D signaling pathway     105539968 (PLD2)    04071 Sphingolipid signaling pathway     105539968 (PLD2)    04024 cAMP signaling pathway     105539968 (PLD2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     105539968 (PLD2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     105539968 (PLD2)   09152 Endocrine system    04912 GnRH signaling pathway     105539968 (PLD2)    04928 Parathyroid hormone synthesis, secretion and action     105539968 (PLD2)   09156 Nervous system    04724 Glutamatergic synapse     105539968 (PLD2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105539968 (PLD2)    05208 Chemical carcinogenesis - reactive oxygen species     105539968 (PLD2)    05231 Choline metabolism in cancer     105539968 (PLD2)   09162 Cancer: specific types    05212 Pancreatic cancer     105539968 (PLD2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mleu04131]     105539968 (PLD2) Enzymes [BR:mleu01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.4  phospholipase D      105539968 (PLD2) Membrane trafficking [BR:mleu04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     105539968 (PLD2)  Endosome - Golgi transport   Others    Others     105539968 (PLD2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLDc PX PLDc_2 PH PH_2 Motif Other DBs NCBI-GeneID:  105539968 NCBI-ProteinID:  XP_011835834 Ensembl:  ENSMLEG00000037390 UniProt:  A0A2K5ZEZ4 LinkDB All DBs Position Unknown AA seq 933 aa AA seqDB search MMATPESLFPTGDELDSSQLQMESDEVDTLREGEDPADRMHPFLAIYELQPLKVHPLVFA PGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLLRHKVL MSLLPLARFAVAYSPAQDAANREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYR NYHALTEFLEVSQLSFIPDLGCKGLEGTIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVV KDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARYGVRIDTSHRSLILKCSSYRQAR WWAQEITELARGPGRDFLQLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIF ITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRAL MLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSPE SAASQPPTPCPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPW RDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQ CTTVQVLRSVDRWSAGTLENSILNAYLHTIKESRHFLYIENQFFISCSDGRTVLNKVGDE IVDRILKAHKQGQCFRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHR LKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKMLIADDRTVIIGSANINDRSLL GKRDSELAVLIEDTETEPSLMNGVEYQAGRFALSLRKHCFSVILGANTRPDLDLRDPVCD DFFQLWQDTAESNANIYEQIFRCLPTNATRSLRTLREYVAVEPLATVSPPLARSELTQVQ GHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT NT seq 2802 nt NT seq  +upstreamnt  +downstreamnt atgatggcgacccctgagagcctcttccccactggggacgaactggactccagccagctc cagatggagtccgacgaggtggacactctgagggagggagaggacccagccgaccggatg cacccgtttctggccatctatgagcttcagcctctgaaagtgcaccccttggtgttcgca cctggggtccctgtcacagcccaggtggtgggcaccgaaagatacaccagcggatccaag gtaggaacctgcactctgtattctgtccgcttgactcacggcgactttacctggacaacc aagaagaagttccgtcattttcaggagctgcatcgggacctcctgagacacaaagtcttg atgagcctgctccctctggctcgttttgccgttgcctattctccagcccaagatgcagcc aacagagagatgccctctctaccccgggcaggtcctgagggctccaccagacatgcagcc agcaaacagaaatacctggagaattacctcaaccgcctcttgaccatgtctttctatcgc aactaccatgccttgacagaattcctggaagtcagtcagctgtcctttatcccagacctg ggctgcaaagggctggaggggacgatccggaagcgctcaggtggccaccgcgttcctggc ctcacctgctgtggccgagaccaagtttgttatcgctggtccaagaggtggctggtggtg aaggactccttcctgctgtacatgtgcctcgagacgggtgccatctcatttgttcagctc tttgaccctggctttgaggtgcaggtggggaaaaggagcacggaggcgcggtacggcgtg cggatcgacacctcccacaggtccttgattctcaagtgcagcagctaccggcaggcacgg tggtgggcccaagagatcactgagctggcgcggggcccaggcagagacttcctacagctg caccagcatgacagctacgccccaccccggcctgggaccttggcccggtggtttgtgaat ggggcaggttactttgctgctgtggcagatgccatccttcgagctcaagaggagattttc atcacagactggtggttgagtcctgaggtttacctgaagcgtccggcccattcagatgac tggagactggacattatgctcaagaggaaggcggaggagggtgtccgcgtgtccattctg ctgtttaaggaagtggaattggccttgggcatcaacagtggctatagcaagagggcactg atgctgctgcaccccaacataaaggtgatgcgtcacccagaccaagtgacgctgtgggcc catcatgagaagctcctggtggtggaccaagtggtagcattcctggggggactggacctt gcctacggccgctgggatgacctgcactaccgactgactgaccttggagactcccctgaa tcagctgcctcccagcctcccaccccgtgcccagactcgccggccaccccagacctctct cacaaccaattcttctggctgggcaaggactacagcaatcttatcaccaaggactgggtg cagctcgaccggcctttcgaagatttcattgacagggagacgacccctcggatgccatgg cgggacgttggggtggtcgtccacggcctacctgcccgggacctcgcccggcacttcatc cagcgctggaacttcaccaagaccaccaaggccaagtacaagactcccacgtacccctac ctgcttcccaagtctaccagcactgccaaccagctccccttcacgctcccaggggggcag tgcaccactgtgcaggtcttgcggtcagtggaccgctggtcagcagggactctggagaac tccatcctcaatgcctacctccacaccatcaaggagagccggcacttcctctacattgag aatcagttcttcattagctgctcagatgggcggacggttctgaacaaggtgggcgatgag attgtggacagaatcctgaaggcccacaaacaggggcagtgtttccgagtctacgtgctt ttgcccttactccctggcttcgagggtgatatctccacgggtggtggcaactccattcag gccattctgcattttacttacaggaccctgtgtcgtggggagtattcaatcctgcatcgc ctcaaagcagccatggggacagcatggcgggactatatttccatctgcgggcttcgtaca cacggagagctgggcgggcaccccgtctcggagctcatctacatccacagcaagatgctc atcgcagatgaccggacagtcatcatcggttctgcaaacatcaatgaccggagcttgctg gggaagcgggacagtgagctggccgtgctgatcgaggacacagagacggaaccatccctc atgaatggggtggagtatcaggcgggcaggtttgccttgagtctgcggaagcactgcttc agtgtgattcttggagcaaatacccggccagacttggatctccgagaccccgtctgtgat gacttcttccagttgtggcaagacacagccgagagcaacgctaatatctatgagcagatc ttccgctgcctaccgaccaatgccacgcgttccctgcggacactccgggagtatgtggcc gtggagcccttggccaccgtcagtcctcccttggctcggtctgagctcacccaggtccag ggccacctggtccacttccccctcaagttcctcgaggacgagtctttgttgcccccgctg ggtagcaaggagggcatgatccccctagaagtgtggacatag

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