KEGG   Mandrillus leucophaeus (drill): 105540494
Entry
105540494         CDS       T08763                                 
Symbol
AKT3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu01521  EGFR tyrosine kinase inhibitor resistance
mleu01522  Endocrine resistance
mleu01524  Platinum drug resistance
mleu04010  MAPK signaling pathway
mleu04012  ErbB signaling pathway
mleu04014  Ras signaling pathway
mleu04015  Rap1 signaling pathway
mleu04022  cGMP-PKG signaling pathway
mleu04024  cAMP signaling pathway
mleu04062  Chemokine signaling pathway
mleu04066  HIF-1 signaling pathway
mleu04068  FoxO signaling pathway
mleu04071  Sphingolipid signaling pathway
mleu04072  Phospholipase D signaling pathway
mleu04140  Autophagy - animal
mleu04150  mTOR signaling pathway
mleu04151  PI3K-Akt signaling pathway
mleu04152  AMPK signaling pathway
mleu04210  Apoptosis
mleu04211  Longevity regulating pathway
mleu04213  Longevity regulating pathway - multiple species
mleu04218  Cellular senescence
mleu04261  Adrenergic signaling in cardiomyocytes
mleu04370  VEGF signaling pathway
mleu04371  Apelin signaling pathway
mleu04380  Osteoclast differentiation
mleu04510  Focal adhesion
mleu04517  IgSF CAM signaling
mleu04518  Integrin signaling
mleu04550  Signaling pathways regulating pluripotency of stem cells
mleu04611  Platelet activation
mleu04613  Neutrophil extracellular trap formation
mleu04620  Toll-like receptor signaling pathway
mleu04625  C-type lectin receptor signaling pathway
mleu04630  JAK-STAT signaling pathway
mleu04660  T cell receptor signaling pathway
mleu04662  B cell receptor signaling pathway
mleu04664  Fc epsilon RI signaling pathway
mleu04666  Fc gamma R-mediated phagocytosis
mleu04668  TNF signaling pathway
mleu04722  Neurotrophin signaling pathway
mleu04725  Cholinergic synapse
mleu04728  Dopaminergic synapse
mleu04810  Regulation of actin cytoskeleton
mleu04910  Insulin signaling pathway
mleu04914  Progesterone-mediated oocyte maturation
mleu04915  Estrogen signaling pathway
mleu04917  Prolactin signaling pathway
mleu04919  Thyroid hormone signaling pathway
mleu04920  Adipocytokine signaling pathway
mleu04922  Glucagon signaling pathway
mleu04923  Regulation of lipolysis in adipocytes
mleu04926  Relaxin signaling pathway
mleu04929  GnRH secretion
mleu04931  Insulin resistance
mleu04932  Non-alcoholic fatty liver disease
mleu04933  AGE-RAGE signaling pathway in diabetic complications
mleu04935  Growth hormone synthesis, secretion and action
mleu04936  Alcoholic liver disease
mleu04973  Carbohydrate digestion and absorption
mleu05010  Alzheimer disease
mleu05017  Spinocerebellar ataxia
mleu05132  Salmonella infection
mleu05135  Yersinia infection
mleu05142  Chagas disease
mleu05145  Toxoplasmosis
mleu05152  Tuberculosis
mleu05160  Hepatitis C
mleu05161  Hepatitis B
mleu05162  Measles
mleu05163  Human cytomegalovirus infection
mleu05164  Influenza A
mleu05165  Human papillomavirus infection
mleu05166  Human T-cell leukemia virus 1 infection
mleu05167  Kaposi sarcoma-associated herpesvirus infection
mleu05168  Herpes simplex virus 1 infection
mleu05169  Epstein-Barr virus infection
mleu05170  Human immunodeficiency virus 1 infection
mleu05200  Pathways in cancer
mleu05205  Proteoglycans in cancer
mleu05207  Chemical carcinogenesis - receptor activation
mleu05208  Chemical carcinogenesis - reactive oxygen species
mleu05210  Colorectal cancer
mleu05211  Renal cell carcinoma
mleu05212  Pancreatic cancer
mleu05213  Endometrial cancer
mleu05214  Glioma
mleu05215  Prostate cancer
mleu05218  Melanoma
mleu05220  Chronic myeloid leukemia
mleu05221  Acute myeloid leukemia
mleu05222  Small cell lung cancer
mleu05223  Non-small cell lung cancer
mleu05224  Breast cancer
mleu05225  Hepatocellular carcinoma
mleu05226  Gastric cancer
mleu05230  Central carbon metabolism in cancer
mleu05231  Choline metabolism in cancer
mleu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mleu05415  Diabetic cardiomyopathy
mleu05417  Lipid and atherosclerosis
mleu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105540494 (AKT3)
   04012 ErbB signaling pathway
    105540494 (AKT3)
   04014 Ras signaling pathway
    105540494 (AKT3)
   04015 Rap1 signaling pathway
    105540494 (AKT3)
   04370 VEGF signaling pathway
    105540494 (AKT3)
   04371 Apelin signaling pathway
    105540494 (AKT3)
   04630 JAK-STAT signaling pathway
    105540494 (AKT3)
   04668 TNF signaling pathway
    105540494 (AKT3)
   04066 HIF-1 signaling pathway
    105540494 (AKT3)
   04068 FoxO signaling pathway
    105540494 (AKT3)
   04072 Phospholipase D signaling pathway
    105540494 (AKT3)
   04071 Sphingolipid signaling pathway
    105540494 (AKT3)
   04024 cAMP signaling pathway
    105540494 (AKT3)
   04022 cGMP-PKG signaling pathway
    105540494 (AKT3)
   04151 PI3K-Akt signaling pathway
    105540494 (AKT3)
   04152 AMPK signaling pathway
    105540494 (AKT3)
   04150 mTOR signaling pathway
    105540494 (AKT3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    105540494 (AKT3)
   04518 Integrin signaling
    105540494 (AKT3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105540494 (AKT3)
  09143 Cell growth and death
   04210 Apoptosis
    105540494 (AKT3)
   04218 Cellular senescence
    105540494 (AKT3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105540494 (AKT3)
   04550 Signaling pathways regulating pluripotency of stem cells
    105540494 (AKT3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105540494 (AKT3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105540494 (AKT3)
   04613 Neutrophil extracellular trap formation
    105540494 (AKT3)
   04620 Toll-like receptor signaling pathway
    105540494 (AKT3)
   04625 C-type lectin receptor signaling pathway
    105540494 (AKT3)
   04660 T cell receptor signaling pathway
    105540494 (AKT3)
   04662 B cell receptor signaling pathway
    105540494 (AKT3)
   04664 Fc epsilon RI signaling pathway
    105540494 (AKT3)
   04666 Fc gamma R-mediated phagocytosis
    105540494 (AKT3)
   04062 Chemokine signaling pathway
    105540494 (AKT3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105540494 (AKT3)
   04922 Glucagon signaling pathway
    105540494 (AKT3)
   04923 Regulation of lipolysis in adipocytes
    105540494 (AKT3)
   04920 Adipocytokine signaling pathway
    105540494 (AKT3)
   04929 GnRH secretion
    105540494 (AKT3)
   04915 Estrogen signaling pathway
    105540494 (AKT3)
   04914 Progesterone-mediated oocyte maturation
    105540494 (AKT3)
   04917 Prolactin signaling pathway
    105540494 (AKT3)
   04926 Relaxin signaling pathway
    105540494 (AKT3)
   04935 Growth hormone synthesis, secretion and action
    105540494 (AKT3)
   04919 Thyroid hormone signaling pathway
    105540494 (AKT3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105540494 (AKT3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    105540494 (AKT3)
  09156 Nervous system
   04725 Cholinergic synapse
    105540494 (AKT3)
   04728 Dopaminergic synapse
    105540494 (AKT3)
   04722 Neurotrophin signaling pathway
    105540494 (AKT3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105540494 (AKT3)
  09149 Aging
   04211 Longevity regulating pathway
    105540494 (AKT3)
   04213 Longevity regulating pathway - multiple species
    105540494 (AKT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105540494 (AKT3)
   05205 Proteoglycans in cancer
    105540494 (AKT3)
   05207 Chemical carcinogenesis - receptor activation
    105540494 (AKT3)
   05208 Chemical carcinogenesis - reactive oxygen species
    105540494 (AKT3)
   05230 Central carbon metabolism in cancer
    105540494 (AKT3)
   05231 Choline metabolism in cancer
    105540494 (AKT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105540494 (AKT3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105540494 (AKT3)
   05212 Pancreatic cancer
    105540494 (AKT3)
   05225 Hepatocellular carcinoma
    105540494 (AKT3)
   05226 Gastric cancer
    105540494 (AKT3)
   05214 Glioma
    105540494 (AKT3)
   05221 Acute myeloid leukemia
    105540494 (AKT3)
   05220 Chronic myeloid leukemia
    105540494 (AKT3)
   05218 Melanoma
    105540494 (AKT3)
   05211 Renal cell carcinoma
    105540494 (AKT3)
   05215 Prostate cancer
    105540494 (AKT3)
   05213 Endometrial cancer
    105540494 (AKT3)
   05224 Breast cancer
    105540494 (AKT3)
   05222 Small cell lung cancer
    105540494 (AKT3)
   05223 Non-small cell lung cancer
    105540494 (AKT3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105540494 (AKT3)
   05170 Human immunodeficiency virus 1 infection
    105540494 (AKT3)
   05161 Hepatitis B
    105540494 (AKT3)
   05160 Hepatitis C
    105540494 (AKT3)
   05164 Influenza A
    105540494 (AKT3)
   05162 Measles
    105540494 (AKT3)
   05168 Herpes simplex virus 1 infection
    105540494 (AKT3)
   05163 Human cytomegalovirus infection
    105540494 (AKT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105540494 (AKT3)
   05169 Epstein-Barr virus infection
    105540494 (AKT3)
   05165 Human papillomavirus infection
    105540494 (AKT3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105540494 (AKT3)
   05135 Yersinia infection
    105540494 (AKT3)
   05152 Tuberculosis
    105540494 (AKT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105540494 (AKT3)
   05142 Chagas disease
    105540494 (AKT3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105540494 (AKT3)
   05017 Spinocerebellar ataxia
    105540494 (AKT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105540494 (AKT3)
   05418 Fluid shear stress and atherosclerosis
    105540494 (AKT3)
   05415 Diabetic cardiomyopathy
    105540494 (AKT3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105540494 (AKT3)
   04932 Non-alcoholic fatty liver disease
    105540494 (AKT3)
   04931 Insulin resistance
    105540494 (AKT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105540494 (AKT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105540494 (AKT3)
   01524 Platinum drug resistance
    105540494 (AKT3)
   01522 Endocrine resistance
    105540494 (AKT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mleu01001]
    105540494 (AKT3)
Enzymes [BR:mleu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     105540494 (AKT3)
Protein kinases [BR:mleu01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   105540494 (AKT3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 ABC1
Other DBs
NCBI-GeneID: 105540494
NCBI-ProteinID: XP_011836548
Ensembl: ENSMLEG00000042542
UniProt: A0A2K6AA78
LinkDB
Position
Unknown
AA seq 479 aa
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aactggaggccaagatatttccttttgaagacagatggctcattcataggatataaagag
aaacctcaagatgtggatttaccttatcccctcaacaacttttcagtggcaaaatgccaa
ttaatgaaaacagaacgaccaaagccaaacacatttataatcagatgtctccagtggacc
actgttatagagagaacatttcatgtagatactccagaggaaagggaagaatggacagaa
gctatccaggctgtagcggacagactgcagaggcaagaagaggagagaatgaattgtagt
ccaacttcacaaattgataatataggagaggaagagatggatgcttctacaacccatcat
aaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcacttttggg
aaagttattttggttcgagagaaggcaagtggaaaatattatgctatgaagattctgaag
aaagaagtcattattgcaaaggatgaagtggcacacactcttactgaaagcagagtatta
aagaacactagacatccctttttaacatccttgaaatattccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgttaatgggggcgagctgtttttccatttgtcgagagag
cgggtgttctctgaggaccgcacacgtttctatggtgcagaaattgtctctgccttggac
tatctacattccggaaagattgtgtaccgtgatctcaagttggagaatctaatgctggat
aaagatggccacataaaaattacagattttggactttgcaaagaagggatcacagatgca
gccaccatgaagacgttctgtggcactccagaatatctggcaccagaggtgttagaagat
aatgactatggccgagcagtagactggtggggcctaggggttgtcatgtatgaaatgatg
tgtgggaggttacctttctacaaccaggaccatgagaaactttttgaactaatattaatg
gaagacattaaatttcctcgaacactctcttcagatgcaaaatcattgctttcagggctc
ttgataaaggatccaaataaacgccttggtggaggaccagatgatgcaaaagaaattatg
agacacagtttcttttctggagtaaactggcaagatgtatatgataaaaagcttgtacct
ccttttaaacctcaagtaacatctgagacagatactagatattttgatgaagaatttaca
gctcagactattacaataacaccacctgaaaaatatgatgaggatggtatggactgcatg
gacaatgagaggcggccgcatttccctcagttttcctactctgcaagtggacgagaataa

DBGET integrated database retrieval system