Mandrillus leucophaeus (drill): 105540597
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Entry
105540597 CDS
T08763
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu00270
Cysteine and methionine metabolism
mleu00480
Glutathione metabolism
mleu01100
Metabolic pathways
mleu01240
Biosynthesis of cofactors
mleu04216
Ferroptosis
Module
mleu_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
105540597 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
105540597 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
105540597 (GCLC)
Enzymes [BR:
mleu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
105540597 (GCLC)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
105540597
NCBI-ProteinID:
XP_011836680
Ensembl:
ENSMLEG00000041190
LinkDB
All DBs
Position
Unknown
AA seq
584 aa
AA seq
DB search
MLVSFDHENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGT
MSEFNTVEANMRKRRKEATSVLEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSL
FFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEASRASKP
DHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDI
DCRWGVISASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKE
IYEQLLQEGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKP
PPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKAA
QKRDAVLQGMFYFRKDICKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPG
LIPILNSYLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVI
TDEMNYSLILKCNQIANELCECPELLGSAFRKVKYGGSKTDSSN
NT seq
1755 nt
NT seq
+upstream
nt +downstream
nt
atgttggtatcttttgatcatgaaaataaaaaagtccgattggtcctgtctggggagaaa
gttcttgaaactctacaagagaagggggaaaggacaaacccaaaccatcctaccctttgg
agaccagagtatgggagttacatgattgaagggacaccaggacagccctacggaggaacg
atgtccgagttcaacacagttgaggccaacatgcgaaaacgccggaaggaggctacttct
gtattagaagaaaatcaggctctttgcacaataacttcatttcccagattaggctgtcct
gggttcacactgcctgaggtcaaacccaacccagtggaaggaggagcttccaagtccctc
ttctttccagatgaagcaataaacaagcaccctcgcttcagtaccttaacaagaaatatc
cgacataggagaggagaaaaggttgtcatcaatgtaccaatatttaaggacaagaataca
ccatctccatttatagaaacatttcctgaggatgatgaagcttcaagggcttctaagcca
gatcatatttacatggatgccatgggatttggaatgggcaattgctgtcttcaggtgaca
ttccaagcctgcagtatatctgaggccagatacctttatgatcagttggctactatctgt
ccaattgtcatggctttgagtgctgcatctcccttttaccgaggctatgtgtcagacatc
gattgtcgctggggagtgatttctgcatctgtagatgatagaactcgggaggagagagga
ctggagccgttgaagaacaataactataggatcagtaaatcccgatatgactcaatagac
agctatttatctaagtgtggtgagaaatataatgacatcgacttgacgatagataaagag
atctacgaacagctgttgcaggaaggcattgatcatctcctggcccagcatgtggctcat
ctctttattagagacccactgacactttttgaagagaaaatacacctggatgatgctaat
gagtctgaccattttgagaatattcagtccacaaattggcagacaatgagatttaagccc
cctcctccaaactcagacatcggatggagagtagaatttcgacccatggaggtgcaatta
acagactttgagaactctgcctatgtggtgttcgtggtactgctcaccagagtgatcctt
tcgtacaaattggattttctcattccactgtcaaaggttgatgagaacatgaaggcagca
cagaaacgagatgctgtcttgcagggaatgttttatttcaggaaagatatttgcaaaggt
ggcaacgcagtggtggatggttgtggcaaggcccagaacagcacagagcttgctgcagag
gagtacaccctcatgagcatagacaccatcatcaatgggaaggaaggtgtgtttcctgga
ctgatcccaattctgaactcttaccttgaaaacatggaagtagatgtggacaccagatgt
agtattctgaactacctaaagctaattaagaagagagcatctggagaactaatgacagtt
gccagatggatgagggagtttatcgcaaaccatcctgactacaagcaagacagtgtcata
actgatgaaatgaattatagccttattttgaagtgtaaccaaattgcaaatgaattatgt
gaatgcccagagttacttggatcagcatttaggaaagtaaaatatggtggaagtaaaact
gactcatccaactag
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