KEGG   Mandrillus leucophaeus (drill): 105540992
Entry
105540992         CDS       T08763                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu01522  Endocrine resistance
mleu04010  MAPK signaling pathway
mleu04014  Ras signaling pathway
mleu04020  Calcium signaling pathway
mleu04024  cAMP signaling pathway
mleu04062  Chemokine signaling pathway
mleu04081  Hormone signaling
mleu04082  Neuroactive ligand signaling
mleu04114  Oocyte meiosis
mleu04140  Autophagy - animal
mleu04211  Longevity regulating pathway
mleu04213  Longevity regulating pathway - multiple species
mleu04261  Adrenergic signaling in cardiomyocytes
mleu04270  Vascular smooth muscle contraction
mleu04310  Wnt signaling pathway
mleu04340  Hedgehog signaling pathway
mleu04371  Apelin signaling pathway
mleu04530  Tight junction
mleu04540  Gap junction
mleu04611  Platelet activation
mleu04713  Circadian entrainment
mleu04714  Thermogenesis
mleu04720  Long-term potentiation
mleu04723  Retrograde endocannabinoid signaling
mleu04724  Glutamatergic synapse
mleu04725  Cholinergic synapse
mleu04726  Serotonergic synapse
mleu04727  GABAergic synapse
mleu04728  Dopaminergic synapse
mleu04740  Olfactory transduction
mleu04742  Taste transduction
mleu04750  Inflammatory mediator regulation of TRP channels
mleu04910  Insulin signaling pathway
mleu04911  Insulin secretion
mleu04912  GnRH signaling pathway
mleu04913  Ovarian steroidogenesis
mleu04914  Progesterone-mediated oocyte maturation
mleu04915  Estrogen signaling pathway
mleu04916  Melanogenesis
mleu04918  Thyroid hormone synthesis
mleu04919  Thyroid hormone signaling pathway
mleu04921  Oxytocin signaling pathway
mleu04922  Glucagon signaling pathway
mleu04923  Regulation of lipolysis in adipocytes
mleu04924  Renin secretion
mleu04925  Aldosterone synthesis and secretion
mleu04926  Relaxin signaling pathway
mleu04927  Cortisol synthesis and secretion
mleu04928  Parathyroid hormone synthesis, secretion and action
mleu04934  Cushing syndrome
mleu04935  Growth hormone synthesis, secretion and action
mleu04961  Endocrine and other factor-regulated calcium reabsorption
mleu04962  Vasopressin-regulated water reabsorption
mleu04970  Salivary secretion
mleu04971  Gastric acid secretion
mleu04976  Bile secretion
mleu05012  Parkinson disease
mleu05020  Prion disease
mleu05030  Cocaine addiction
mleu05031  Amphetamine addiction
mleu05032  Morphine addiction
mleu05034  Alcoholism
mleu05146  Amoebiasis
mleu05163  Human cytomegalovirus infection
mleu05165  Human papillomavirus infection
mleu05166  Human T-cell leukemia virus 1 infection
mleu05200  Pathways in cancer
mleu05203  Viral carcinogenesis
mleu05205  Proteoglycans in cancer
mleu05207  Chemical carcinogenesis - receptor activation
mleu05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105540992 (PRKACA)
   04014 Ras signaling pathway
    105540992 (PRKACA)
   04310 Wnt signaling pathway
    105540992 (PRKACA)
   04340 Hedgehog signaling pathway
    105540992 (PRKACA)
   04371 Apelin signaling pathway
    105540992 (PRKACA)
   04020 Calcium signaling pathway
    105540992 (PRKACA)
   04024 cAMP signaling pathway
    105540992 (PRKACA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    105540992 (PRKACA)
   04081 Hormone signaling
    105540992 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105540992 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    105540992 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    105540992 (PRKACA)
   04540 Gap junction
    105540992 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105540992 (PRKACA)
   04062 Chemokine signaling pathway
    105540992 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    105540992 (PRKACA)
   04910 Insulin signaling pathway
    105540992 (PRKACA)
   04922 Glucagon signaling pathway
    105540992 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    105540992 (PRKACA)
   04912 GnRH signaling pathway
    105540992 (PRKACA)
   04913 Ovarian steroidogenesis
    105540992 (PRKACA)
   04915 Estrogen signaling pathway
    105540992 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    105540992 (PRKACA)
   04921 Oxytocin signaling pathway
    105540992 (PRKACA)
   04926 Relaxin signaling pathway
    105540992 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    105540992 (PRKACA)
   04918 Thyroid hormone synthesis
    105540992 (PRKACA)
   04919 Thyroid hormone signaling pathway
    105540992 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    105540992 (PRKACA)
   04916 Melanogenesis
    105540992 (PRKACA)
   04924 Renin secretion
    105540992 (PRKACA)
   04925 Aldosterone synthesis and secretion
    105540992 (PRKACA)
   04927 Cortisol synthesis and secretion
    105540992 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105540992 (PRKACA)
   04270 Vascular smooth muscle contraction
    105540992 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    105540992 (PRKACA)
   04971 Gastric acid secretion
    105540992 (PRKACA)
   04976 Bile secretion
    105540992 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    105540992 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    105540992 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    105540992 (PRKACA)
   04727 GABAergic synapse
    105540992 (PRKACA)
   04725 Cholinergic synapse
    105540992 (PRKACA)
   04728 Dopaminergic synapse
    105540992 (PRKACA)
   04726 Serotonergic synapse
    105540992 (PRKACA)
   04720 Long-term potentiation
    105540992 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    105540992 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    105540992 (PRKACA)
   04742 Taste transduction
    105540992 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    105540992 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    105540992 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    105540992 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105540992 (PRKACA)
   04714 Thermogenesis
    105540992 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105540992 (PRKACA)
   05205 Proteoglycans in cancer
    105540992 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    105540992 (PRKACA)
   05203 Viral carcinogenesis
    105540992 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105540992 (PRKACA)
   05163 Human cytomegalovirus infection
    105540992 (PRKACA)
   05165 Human papillomavirus infection
    105540992 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    105540992 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    105540992 (PRKACA)
   05020 Prion disease
    105540992 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    105540992 (PRKACA)
   05031 Amphetamine addiction
    105540992 (PRKACA)
   05032 Morphine addiction
    105540992 (PRKACA)
   05034 Alcoholism
    105540992 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    105540992 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    105540992 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105540992 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mleu01001]
    105540992 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mleu03019]
    105540992 (PRKACA)
   03036 Chromosome and associated proteins [BR:mleu03036]
    105540992 (PRKACA)
Enzymes [BR:mleu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     105540992 (PRKACA)
Protein kinases [BR:mleu01001]
 Serine/threonine kinases: AGC group
  PKA family
   105540992 (PRKACA)
Messenger RNA biogenesis [BR:mleu03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     105540992 (PRKACA)
Chromosome and associated proteins [BR:mleu03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    105540992 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 105540992
NCBI-ProteinID: XP_011837175
Ensembl: ENSMLEG00000034529
LinkDB
Position
Unknown
AA seq 402 aa
MPLRLTREEQGQLGAKVTAEPPKGACYPSPRGLHPRPGLPREGARGTAKSQGYKYLGWRR
PWPWNVVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVRHKETGNH
YAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEM
FSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA
KRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYE
KIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQR
KVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
NT seq 1209 nt   +upstreamnt  +downstreamnt
atgcccttgcgattgacacgagaggaacagggccagctgggggccaaggtgacagctgag
ccccccaagggcgcctgctacccgagcccccgaggcctccatcccaggcccggcctcccc
agagaaggggccagaggaacagccaaatcccaaggctataaatacctcggctggcgtcgg
ccctggccgtggaatgtcgtgaaagaattcttagccaaagccaaagaagattttcttaaa
aaatgggaaagtcccgctcagaacacagcccacttggatcagtttgaacgaatcaagacc
ctcggcacgggctccttcgggcgggtgatgctggtgagacacaaggagaccgggaaccac
tatgccatgaagatcctcgacaaacagaaggtggtgaagctgaaacagatcgaacatacc
ctgaatgaaaagcgcatcctgcaagccgtcaactttccgttcctcgtcaaactcgagttc
tccttcaaggacaactcaaacttatacatggtcatggaatacgtgcccggtggggagatg
ttctcacacctacggcggattggaaggttcagcgagccccatgcccgtttctacgcggcc
cagatcgtcctgaccttcgagtatctgcactcgctggatctcatctacagggacctgaag
ccagagaatctgctcattgaccagcagggatacattcaggtgacagacttcggtttcgcc
aagcgcgtgaagggccgcacttggaccttgtgcggcacccctgagtatctggcccctgag
attatcctgagcaaaggctacaacaaggctgtggactggtgggccctgggggttcttatc
tatgaaatggccgctggctacccgcccttcttcgcagaccagcccatccagatctatgag
aagatcgtctctgggaaggtgcggttcccttcccacttcagctctgacttgaaggacctg
ctgcggaacctcctgcaggtagatcttaccaagcgctttgggaacctcaagaatggggtc
aatgatatcaagaaccacaagtggtttgccacgactgactggatcgccatctaccagagg
aaggtggaagctcccttcataccaaagtttaaaggccctggggatacgagtaactttgac
gactatgaggaagaagaaatccgggtctccatcaatgagaagtgtggcaaggagttttct
gagttttag

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