Mandrillus leucophaeus (drill): 105541755
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Entry
105541755 CDS
T08763
Symbol
AKT1
Name
(RefSeq) RAC-alpha serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu01521
EGFR tyrosine kinase inhibitor resistance
mleu01522
Endocrine resistance
mleu01524
Platinum drug resistance
mleu04010
MAPK signaling pathway
mleu04012
ErbB signaling pathway
mleu04014
Ras signaling pathway
mleu04015
Rap1 signaling pathway
mleu04022
cGMP-PKG signaling pathway
mleu04024
cAMP signaling pathway
mleu04062
Chemokine signaling pathway
mleu04066
HIF-1 signaling pathway
mleu04068
FoxO signaling pathway
mleu04071
Sphingolipid signaling pathway
mleu04072
Phospholipase D signaling pathway
mleu04140
Autophagy - animal
mleu04150
mTOR signaling pathway
mleu04151
PI3K-Akt signaling pathway
mleu04152
AMPK signaling pathway
mleu04210
Apoptosis
mleu04211
Longevity regulating pathway
mleu04213
Longevity regulating pathway - multiple species
mleu04218
Cellular senescence
mleu04261
Adrenergic signaling in cardiomyocytes
mleu04370
VEGF signaling pathway
mleu04371
Apelin signaling pathway
mleu04380
Osteoclast differentiation
mleu04510
Focal adhesion
mleu04550
Signaling pathways regulating pluripotency of stem cells
mleu04611
Platelet activation
mleu04613
Neutrophil extracellular trap formation
mleu04620
Toll-like receptor signaling pathway
mleu04625
C-type lectin receptor signaling pathway
mleu04630
JAK-STAT signaling pathway
mleu04660
T cell receptor signaling pathway
mleu04662
B cell receptor signaling pathway
mleu04664
Fc epsilon RI signaling pathway
mleu04666
Fc gamma R-mediated phagocytosis
mleu04668
TNF signaling pathway
mleu04722
Neurotrophin signaling pathway
mleu04725
Cholinergic synapse
mleu04728
Dopaminergic synapse
mleu04810
Regulation of actin cytoskeleton
mleu04910
Insulin signaling pathway
mleu04914
Progesterone-mediated oocyte maturation
mleu04915
Estrogen signaling pathway
mleu04917
Prolactin signaling pathway
mleu04919
Thyroid hormone signaling pathway
mleu04920
Adipocytokine signaling pathway
mleu04922
Glucagon signaling pathway
mleu04923
Regulation of lipolysis in adipocytes
mleu04926
Relaxin signaling pathway
mleu04929
GnRH secretion
mleu04931
Insulin resistance
mleu04932
Non-alcoholic fatty liver disease
mleu04933
AGE-RAGE signaling pathway in diabetic complications
mleu04935
Growth hormone synthesis, secretion and action
mleu04936
Alcoholic liver disease
mleu04973
Carbohydrate digestion and absorption
mleu05010
Alzheimer disease
mleu05017
Spinocerebellar ataxia
mleu05132
Salmonella infection
mleu05135
Yersinia infection
mleu05142
Chagas disease
mleu05145
Toxoplasmosis
mleu05152
Tuberculosis
mleu05160
Hepatitis C
mleu05161
Hepatitis B
mleu05162
Measles
mleu05163
Human cytomegalovirus infection
mleu05164
Influenza A
mleu05165
Human papillomavirus infection
mleu05166
Human T-cell leukemia virus 1 infection
mleu05167
Kaposi sarcoma-associated herpesvirus infection
mleu05168
Herpes simplex virus 1 infection
mleu05169
Epstein-Barr virus infection
mleu05170
Human immunodeficiency virus 1 infection
mleu05200
Pathways in cancer
mleu05205
Proteoglycans in cancer
mleu05207
Chemical carcinogenesis - receptor activation
mleu05208
Chemical carcinogenesis - reactive oxygen species
mleu05210
Colorectal cancer
mleu05211
Renal cell carcinoma
mleu05212
Pancreatic cancer
mleu05213
Endometrial cancer
mleu05214
Glioma
mleu05215
Prostate cancer
mleu05218
Melanoma
mleu05220
Chronic myeloid leukemia
mleu05221
Acute myeloid leukemia
mleu05222
Small cell lung cancer
mleu05223
Non-small cell lung cancer
mleu05224
Breast cancer
mleu05225
Hepatocellular carcinoma
mleu05226
Gastric cancer
mleu05230
Central carbon metabolism in cancer
mleu05231
Choline metabolism in cancer
mleu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mleu05415
Diabetic cardiomyopathy
mleu05417
Lipid and atherosclerosis
mleu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105541755 (AKT1)
04012 ErbB signaling pathway
105541755 (AKT1)
04014 Ras signaling pathway
105541755 (AKT1)
04015 Rap1 signaling pathway
105541755 (AKT1)
04370 VEGF signaling pathway
105541755 (AKT1)
04371 Apelin signaling pathway
105541755 (AKT1)
04630 JAK-STAT signaling pathway
105541755 (AKT1)
04668 TNF signaling pathway
105541755 (AKT1)
04066 HIF-1 signaling pathway
105541755 (AKT1)
04068 FoxO signaling pathway
105541755 (AKT1)
04072 Phospholipase D signaling pathway
105541755 (AKT1)
04071 Sphingolipid signaling pathway
105541755 (AKT1)
04024 cAMP signaling pathway
105541755 (AKT1)
04022 cGMP-PKG signaling pathway
105541755 (AKT1)
04151 PI3K-Akt signaling pathway
105541755 (AKT1)
04152 AMPK signaling pathway
105541755 (AKT1)
04150 mTOR signaling pathway
105541755 (AKT1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105541755 (AKT1)
09143 Cell growth and death
04210 Apoptosis
105541755 (AKT1)
04218 Cellular senescence
105541755 (AKT1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
105541755 (AKT1)
04550 Signaling pathways regulating pluripotency of stem cells
105541755 (AKT1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
105541755 (AKT1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
105541755 (AKT1)
04613 Neutrophil extracellular trap formation
105541755 (AKT1)
04620 Toll-like receptor signaling pathway
105541755 (AKT1)
04625 C-type lectin receptor signaling pathway
105541755 (AKT1)
04660 T cell receptor signaling pathway
105541755 (AKT1)
04662 B cell receptor signaling pathway
105541755 (AKT1)
04664 Fc epsilon RI signaling pathway
105541755 (AKT1)
04666 Fc gamma R-mediated phagocytosis
105541755 (AKT1)
04062 Chemokine signaling pathway
105541755 (AKT1)
09152 Endocrine system
04910 Insulin signaling pathway
105541755 (AKT1)
04922 Glucagon signaling pathway
105541755 (AKT1)
04923 Regulation of lipolysis in adipocytes
105541755 (AKT1)
04920 Adipocytokine signaling pathway
105541755 (AKT1)
04929 GnRH secretion
105541755 (AKT1)
04915 Estrogen signaling pathway
105541755 (AKT1)
04914 Progesterone-mediated oocyte maturation
105541755 (AKT1)
04917 Prolactin signaling pathway
105541755 (AKT1)
04926 Relaxin signaling pathway
105541755 (AKT1)
04935 Growth hormone synthesis, secretion and action
105541755 (AKT1)
04919 Thyroid hormone signaling pathway
105541755 (AKT1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
105541755 (AKT1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
105541755 (AKT1)
09156 Nervous system
04725 Cholinergic synapse
105541755 (AKT1)
04728 Dopaminergic synapse
105541755 (AKT1)
04722 Neurotrophin signaling pathway
105541755 (AKT1)
09158 Development and regeneration
04380 Osteoclast differentiation
105541755 (AKT1)
09149 Aging
04211 Longevity regulating pathway
105541755 (AKT1)
04213 Longevity regulating pathway - multiple species
105541755 (AKT1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105541755 (AKT1)
05205 Proteoglycans in cancer
105541755 (AKT1)
05207 Chemical carcinogenesis - receptor activation
105541755 (AKT1)
05208 Chemical carcinogenesis - reactive oxygen species
105541755 (AKT1)
05230 Central carbon metabolism in cancer
105541755 (AKT1)
05231 Choline metabolism in cancer
105541755 (AKT1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105541755 (AKT1)
09162 Cancer: specific types
05210 Colorectal cancer
105541755 (AKT1)
05212 Pancreatic cancer
105541755 (AKT1)
05225 Hepatocellular carcinoma
105541755 (AKT1)
05226 Gastric cancer
105541755 (AKT1)
05214 Glioma
105541755 (AKT1)
05221 Acute myeloid leukemia
105541755 (AKT1)
05220 Chronic myeloid leukemia
105541755 (AKT1)
05218 Melanoma
105541755 (AKT1)
05211 Renal cell carcinoma
105541755 (AKT1)
05215 Prostate cancer
105541755 (AKT1)
05213 Endometrial cancer
105541755 (AKT1)
05224 Breast cancer
105541755 (AKT1)
05222 Small cell lung cancer
105541755 (AKT1)
05223 Non-small cell lung cancer
105541755 (AKT1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
105541755 (AKT1)
05170 Human immunodeficiency virus 1 infection
105541755 (AKT1)
05161 Hepatitis B
105541755 (AKT1)
05160 Hepatitis C
105541755 (AKT1)
05164 Influenza A
105541755 (AKT1)
05162 Measles
105541755 (AKT1)
05168 Herpes simplex virus 1 infection
105541755 (AKT1)
05163 Human cytomegalovirus infection
105541755 (AKT1)
05167 Kaposi sarcoma-associated herpesvirus infection
105541755 (AKT1)
05169 Epstein-Barr virus infection
105541755 (AKT1)
05165 Human papillomavirus infection
105541755 (AKT1)
09171 Infectious disease: bacterial
05132 Salmonella infection
105541755 (AKT1)
05135 Yersinia infection
105541755 (AKT1)
05152 Tuberculosis
105541755 (AKT1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
105541755 (AKT1)
05142 Chagas disease
105541755 (AKT1)
09164 Neurodegenerative disease
05010 Alzheimer disease
105541755 (AKT1)
05017 Spinocerebellar ataxia
105541755 (AKT1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105541755 (AKT1)
05418 Fluid shear stress and atherosclerosis
105541755 (AKT1)
05415 Diabetic cardiomyopathy
105541755 (AKT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
105541755 (AKT1)
04932 Non-alcoholic fatty liver disease
105541755 (AKT1)
04931 Insulin resistance
105541755 (AKT1)
04933 AGE-RAGE signaling pathway in diabetic complications
105541755 (AKT1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105541755 (AKT1)
01524 Platinum drug resistance
105541755 (AKT1)
01522 Endocrine resistance
105541755 (AKT1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mleu01001
]
105541755 (AKT1)
Enzymes [BR:
mleu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105541755 (AKT1)
Protein kinases [BR:
mleu01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
105541755 (AKT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Seadorna_VP7
ABC1
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
105541755
NCBI-ProteinID:
XP_011838308
LinkDB
All DBs
Position
Unknown
AA seq
300 aa
AA seq
DB search
MVSGNVHGIGQRGVGLLSCPWGCGSSSASLQALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
NT seq
903 nt
NT seq
+upstream
nt +downstream
nt
atggtatcgggcaatgtgcatggtatcgggcagcgtggtgtggggctgctgtcctgcccg
tggggctgcggttccagctccgcttccttgcaggccctgaagtactccttccagacccac
gaccgcctctgcttcgtcatggagtacgccaatgggggcgagctcttcttccacctgtcc
cgggagcgtgtgttctctgaggaccgggcccgcttctatggcgccgagatcgtgtcagcc
ctggactacctgcattcggagaagaatgtggtgtaccgggacctcaagctggagaacctc
atgctggacaaggacgggcacattaagatcacagactttgggctgtgcaaggaggggatc
aaggacggcgccaccatgaagaccttctgcggcacacctgagtacctggcccccgaggtg
ctggaggacaatgactacggccgtgcggtggactggtgggggctgggcgtggtcatgtat
gagatgatgtgcggccgcctgcccttctacaaccaggaccacgagaagctttttgagctc
atcctcatggaagagatccgcttcccgcgcacgcttggtcctgaggccaagtccttgctc
tcagggctgctcaagaaggaccccaagcagaggcttggcgggggctctgaggacgccaag
gagatcatgcagcatcgcttctttgccggcatcgtgtggcagcacgtgtatgagaagaag
ctcagcccacccttcaagccccaggtcacatcggagaccgacaccaggtattttgatgag
gagttcacggcccagatgatcaccatcacaccacctgaccaagacgacagcatggagtgc
gtggacagcgagcgcaggccccacttcccccagttctcctactcggccagcggcacggcc
tga
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integrated database retrieval system