Mandrillus leucophaeus (drill): 105542707
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Entry
105542707 CDS
T08763
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu00220
Arginine biosynthesis
mleu00330
Arginine and proline metabolism
mleu01100
Metabolic pathways
mleu04020
Calcium signaling pathway
mleu04022
cGMP-PKG signaling pathway
mleu04066
HIF-1 signaling pathway
mleu04071
Sphingolipid signaling pathway
mleu04151
PI3K-Akt signaling pathway
mleu04370
VEGF signaling pathway
mleu04371
Apelin signaling pathway
mleu04611
Platelet activation
mleu04915
Estrogen signaling pathway
mleu04921
Oxytocin signaling pathway
mleu04926
Relaxin signaling pathway
mleu04931
Insulin resistance
mleu04933
AGE-RAGE signaling pathway in diabetic complications
mleu05415
Diabetic cardiomyopathy
mleu05417
Lipid and atherosclerosis
mleu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
105542707 (NOS3)
00330 Arginine and proline metabolism
105542707 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
105542707 (NOS3)
04371 Apelin signaling pathway
105542707 (NOS3)
04066 HIF-1 signaling pathway
105542707 (NOS3)
04020 Calcium signaling pathway
105542707 (NOS3)
04071 Sphingolipid signaling pathway
105542707 (NOS3)
04022 cGMP-PKG signaling pathway
105542707 (NOS3)
04151 PI3K-Akt signaling pathway
105542707 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
105542707 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
105542707 (NOS3)
04921 Oxytocin signaling pathway
105542707 (NOS3)
04926 Relaxin signaling pathway
105542707 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105542707 (NOS3)
05418 Fluid shear stress and atherosclerosis
105542707 (NOS3)
05415 Diabetic cardiomyopathy
105542707 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
105542707 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
105542707 (NOS3)
Enzymes [BR:
mleu01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
105542707 (NOS3)
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Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
105542707
NCBI-ProteinID:
XP_011839741
Ensembl:
ENSMLEG00000031185
LinkDB
All DBs
Position
Unknown
AA seq
1204 aa
AA seq
DB search
MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPAPSAPEPSRAPASLPPPAPEHSPPPFPLF
HPCTLPPSPPFLSHPCSLAWPDLCTPSTQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE
QLLSQARDFINQYYSSIRRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA
PRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDF
RIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPE
LFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTE
IGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH
AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWK
GSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRL
FRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSP
RPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFC
AFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAAR
DIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTRATILV
RLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGPP
PGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRYE
EWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLA
YRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPF
RGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREP
DNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELDE
AGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDTN
TNGP
NT seq
3615 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtggcccaggaacctgggccaccctgtggcctgggactgggg
ctgggccttgggctatgcggcaagcagggcccagccccctcagcccctgagcccagccgg
gccccggcatccctacccccgccagcaccagaacacagccctcctccctttcccctgttc
cacccatgcacccttcctccctctcccccattcctgtcccacccctgctccctggcctgg
cctgacctttgcactccctcgacccaggatgggccctgcaccccaagacgctgcctgggc
tccctggtatttccacggaaactacagggccggccctcccctggccccccggcccctgag
cagctgctgagtcaggcccgggacttcatcaaccagtactacagctccatcaggaggagc
ggctcccaggcccacgaacagcggcttcaagaggtggaagccgaggtggcagccacaggc
acctaccagcttagggagagcgagctcgtgttcggggccaagcaggcctggcgcaacgct
ccccgctgtgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggactgc
aggtctgcacaggaaatgttcacctacatctgcaaccacatcaaatacgccaccaaccgg
ggcaaccttcgctcggccatcacagtgttcccgcagcgctgccctggccgaggagacttc
cgaatctggaacagccagctggtgcgctatgcgggctaccggcagcaggacggctctgtg
cggggggacccagccaacgtcgagatcaccgagctctgcattcagcatggctggacccca
ggaaacggtcgctttgacgtgctgcccctgctgctgcaggccccggatgagcccccggaa
ctcttccttctgccccctgagctggtccttgaggtgcccctggagcaccctacgctggag
tggtttgcagccctgggcctgcgctggtatgccctcccagcagtgtccaacatgctgctg
gaaattgggggcctggagttccccgcagcccccttcagtggctggtacatgagcactgag
atcggcacgaggaacctgtgtgaccctcaccgctacaacatcctggaggacgtggctgtc
tgcatggacctggatacccggacaacttcatccctatggaaagacaaggcagcggtggaa
atcaacgtggccgtgctgcacagttaccagctggccaaagtcaccattgtggaccaccac
gccgccacagcctccttcatgaagcacctggagaatgagcagaaggccagggggggctgc
cctgcagactgggcctggatcgtgccccccatctcgggcagcctcactcctgtcttccat
caggagatggtcaactatttcctgtccccagccttccgctaccagccagacccctggaag
gggagtgcggccaagggcaccggcatcaccaggaagaagacctttaaagaagtggccaat
gccgtgaagatctctgcctcgctcatgggcaccgtgatggcgaagcgagtgaaggcaaca
atcctgtatggctccgagaccggccgggcccagagctacgcacagcagctggggagactt
ttccggaaggcttttgatccccgggtcctgtgtatggatgagtatgacgtggtgtccctc
gaacacgagacgctggtgctggtggtaaccagcacattcgggaatggggatcccccggag
aatggagagagctttgcagctgccctgatggagatgtccggtccctacaacagctcccct
cggccggaacagcacaagagttataagatccgcttcaacagcatctcctgctcagaccca
ctggtgtcctcttggcggcggaagaggaaggagtccagtaacacagacagtgcaggagcc
ctgggcacactcaggttctgtgtgttcgggctgggctcccgggcctacccccacttctgc
gcctttgctcgtgcggtggacacgcgactggaggaactgggcggggagcggctgctgcag
ctgggccagggcgacgagctgtgtggccaggaggaggccttccgcggctgggcccaggct
gccttccaggccgcctgtgagaccttctgtgtgggagaggatgccaaggctgctgcccga
gacatcttcagccccaaaaggagttggaagcgccagaggtaccggctgagcgcccaggcc
gagggcctgcagttgctgccaggtctgatccacgtgcacaggcggaagatgttccaggct
acaattctctcagtggaaaacctgcaaagcagcaagtccacgagggccaccatcctggtg
cgcctggacactggaggccaagaggggctgcagtaccagccgggggaccacataggtgtc
tgcccacccaaccgacccggccttgtggaggcgctgctgagccgcgtggaggacccgcct
gcgcccaccgagcccgtggcagtagagcaactggagaagggcagccctggtggccctccc
cccggctgggtgcgggacccccggctgcccccatgcacgctgcgccaggctctcaccttc
ttcctggacatcacctccccgcccagccctcagctcttgcggctgctcagcaccttggca
gaagagcccagggaacagcaggagctggaggccctcagtcaggatccccgacgctacgag
gagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccttcagtg
gcactgcctgccccactgctcctcacccagctgcctctgctccaaccccggtactactca
gtcagctcagcacccagcacccacccaggagagatccacctcactgtagctgtgctggca
tacaggacccaggatgggctgggccccctgcactatggagtctgctccacgtggctaagc
caactcaagcccggagaccctgtgccctgcttcatccggggggctccctccttccggctg
ccacctgatcccagcttgccctgcatcctggtgggcccaggcactggcattgcccccttc
cggggattctggcaggagcggctgcatgacattgagagcaaagggctgcagcccactccc
atgactttggtgtttggctgccgatgctcccaactcgaccatctctaccgcgacgaggtg
cagaacgcccagcagcgcggggtgtttggccgagtcctcaccgccttctcccgggaacct
gacaaccccaagacctacgtgcaggacatcctgaggacggagctggctgcggaggtgcac
cgcgtgctgtgcctcgagcggggccacatgtttgtctgcggagatgtcaccatggcaacc
aacgtcctgcagaccgtgcagcgcatcctggcaacggagggcgacatggagctggacgag
gccggcgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaagacattttcggg
ctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagcttttccttgcag
gagcggcagctacggggcgcagtgccctgggcgttcgacccgcccggctcggacaccaac
accaacggcccctga
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integrated database retrieval system
