Mandrillus leucophaeus (drill): 105543978
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Entry
105543978 CDS
T08763
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu04010
MAPK signaling pathway
mleu04020
Calcium signaling pathway
mleu04022
cGMP-PKG signaling pathway
mleu04024
cAMP signaling pathway
mleu04218
Cellular senescence
mleu04260
Cardiac muscle contraction
mleu04261
Adrenergic signaling in cardiomyocytes
mleu04270
Vascular smooth muscle contraction
mleu04530
Tight junction
mleu04713
Circadian entrainment
mleu04723
Retrograde endocannabinoid signaling
mleu04724
Glutamatergic synapse
mleu04725
Cholinergic synapse
mleu04726
Serotonergic synapse
mleu04727
GABAergic synapse
mleu04728
Dopaminergic synapse
mleu04911
Insulin secretion
mleu04912
GnRH signaling pathway
mleu04921
Oxytocin signaling pathway
mleu04924
Renin secretion
mleu04925
Aldosterone synthesis and secretion
mleu04927
Cortisol synthesis and secretion
mleu04929
GnRH secretion
mleu04930
Type II diabetes mellitus
mleu04934
Cushing syndrome
mleu04935
Growth hormone synthesis, secretion and action
mleu04973
Carbohydrate digestion and absorption
mleu05010
Alzheimer disease
mleu05020
Prion disease
mleu05022
Pathways of neurodegeneration - multiple diseases
mleu05031
Amphetamine addiction
mleu05207
Chemical carcinogenesis - receptor activation
mleu05410
Hypertrophic cardiomyopathy
mleu05412
Arrhythmogenic right ventricular cardiomyopathy
mleu05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105543978 (CACNA1D)
04020 Calcium signaling pathway
105543978 (CACNA1D)
04024 cAMP signaling pathway
105543978 (CACNA1D)
04022 cGMP-PKG signaling pathway
105543978 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
105543978 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
105543978 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
105543978 (CACNA1D)
04929 GnRH secretion
105543978 (CACNA1D)
04912 GnRH signaling pathway
105543978 (CACNA1D)
04921 Oxytocin signaling pathway
105543978 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
105543978 (CACNA1D)
04924 Renin secretion
105543978 (CACNA1D)
04925 Aldosterone synthesis and secretion
105543978 (CACNA1D)
04927 Cortisol synthesis and secretion
105543978 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
105543978 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
105543978 (CACNA1D)
04270 Vascular smooth muscle contraction
105543978 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
105543978 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
105543978 (CACNA1D)
04727 GABAergic synapse
105543978 (CACNA1D)
04725 Cholinergic synapse
105543978 (CACNA1D)
04728 Dopaminergic synapse
105543978 (CACNA1D)
04726 Serotonergic synapse
105543978 (CACNA1D)
04723 Retrograde endocannabinoid signaling
105543978 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
105543978 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
105543978 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
105543978 (CACNA1D)
05020 Prion disease
105543978 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
105543978 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
105543978 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
105543978 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
105543978 (CACNA1D)
05414 Dilated cardiomyopathy
105543978 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
105543978 (CACNA1D)
04934 Cushing syndrome
105543978 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mleu04040
]
105543978 (CACNA1D)
Ion channels [BR:
mleu04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
105543978 (CACNA1D)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
NCAPD3_N
Motif
Other DBs
NCBI-GeneID:
105543978
NCBI-ProteinID:
XP_011841569
Ensembl:
ENSMLEG00000033889
UniProt:
A0A2K5YVZ2
LinkDB
All DBs
Position
Unknown
AA seq
2181 aa
AA seq
DB search
MMMMMMMKKMQHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRNTSMPTSETESVNTENVS
GEGETRGCCGSLWCWWRRRGAAKAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQMANSDNKVTIDDYREEDEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCH
KLINHHVFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGP
IYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENVPVP
TATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAML
FFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKL
CDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPH
HLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNS
DGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDE
VTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISC
DLQDDEPEETKREEEDDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPP
ASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHV
SENGHHSSHKHDREPQRRSSVKRTRYYETYIRSDSGDEQLPTICREDPEIHGYFRDPRCF
GEQEYFSSEECYEDDSSPTWSRQNYGYYSRYPGRNVDFERPRGYHHPQGFLEDDDSPICY
DSRRSPRRRLLPPTPASHRRSSFNFECLRRQSSQEEVPSSPTFPHRTALPLHLMQQQIMA
VAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVEQLEALDQMNGSLPSLH
RSSWYTDEPDISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKF
VSATKHEIADACDLTIDEMESAASTLLNGNVCPRANGDVGPLSHRQDYELQDFGPGYSDE
EPDPGRDEEDLADEMICITTL
NT seq
6546 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaactgtcctgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctctgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttatcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcgtatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcgggaaccactctagcggcaagtctggaggctttgatgtcaaagccctccgt
gcctttcgagtgttgcgaccacttcgactagtgtcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatcgtagctgaagaggacccagctccatgtgcgttctca
gggaacggacgccagtgtactgccaatggcacggaatgtaggagtggctgggttggcccg
aacggaggcatcaccaactttgataactttgcctttgctatgctcactgtgtttcagtgc
atcaccatggagggctggacagatgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctcatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctcaaaggaaagagagaaggcaaaagcacgggga
gatttccagaagctccgggagaagcagcagctggaggaggatctaaagggctacttggat
tggatcacccaagctgaggacatcgatcccgagaacgaggaagaaggaggagaggaaggc
aaacgaaatactagcatgcccaccagtgagactgagtctgtgaacacagagaacgtcagc
ggcgaaggcgagacccgaggctgctgtggaagtctctggtgctggtggagacggagaggc
gcggccaaggcggggccctctgggtgtcggcggtggggtcaagccatctcaaaatccaaa
ctcagccgacgctggcgtcgctggaaccgattcaatcgcagaagatgtagggccgccgtg
aagtctgtcacgttttactggctggttatcgtcctggtgtttctgaacaccttaaccatt
tcctctgagcactacaatcaaccggattggttgacacagattcaagatattgccaacaaa
gtcctcttggctctgttcacctgcgagatgctggtaaaaatgtacagcttgggcctccaa
gcatatttcgtctctcttttcaaccggtttgattgcttcgtggtgtgtggtggaatcact
gagacgatcttggtggaactggaaatcatgtctcccctggggatctctgtgtttcggtgt
gtgcgcctcttaagaatcttcaaggtgaccaggcactggacttctctgagcaacttagtg
gcatccttgttaaactccatgaagtccatcgcttcgctgttacttctgctttttctcttc
attatcatcttttccttgcttgggatgcagctgtttggtggcaagtttaattttgatgaa
acgcaaaccaagcggagcacctttgacaatttccctcaagcacttctcacagtgttccag
atcctgacaggcgaagactggaacgctgtgatgtacgatggcatcatggcttacgggggc
ccgtcctcttcaggaatgatcgtctgcatctacttcatcatcctcttcatttgtggtaat
tatattctactgaatgtcttcttggccatcgctgtagacaatttggctgatgctgaaagt
ttgaacactgctcagaaagaagaagcagaagaaaaggagaggaaaaagattgccagaaaa
gagagcctagaaaataaaaagaacaacaaaccagaagtcaaccagatggccaacagtgac
aacaaggttacaatcgatgactatagagaagaggatgaagacaaggacccctacccacct
tgcgatgtgccagtaggggaagaggaagaggaagaggaggaggatgaacctgaggttcct
gccggaccccgtcctcgaaggatctcggagttgaacatgaaggaaaaaattgcccccatc
cctgaagggagcgctttcttcattcttagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccaccacgtcttcaccaacctcatcctcgtcttcatcatgctgagcagc
gccgctctggccgcagaggaccccatccgcagccactccttccggaacacgatactgggt
tactttgactatgccttcacagccatctttactgttgagatcctgctgaagatgacaact
tttggagctttcctccacaaaggggccttctgcaggaactacttcaatttgctggatatg
ctcgtggttggggtgtctctggtgtcatttgggattcaatccagtgccatctctgttgtg
aagattctcagagtcttaagggtcctgaggcccctcagggccatcaacagagcaaaagga
cttaagcacgtggtccagtgcgtcttcgtggccatccggaccatcggcaacatcatgatc
gtcaccaccctcctccagttcatgtttgcctgtattggggtccagttgttcaaggggaag
ttctatcgctgtacggatgaagccaaaagtaaccctgaagaatgcaggggacttttcatc
ctctacaaggatggggatgttgacagtcctgtggtccgtgagcggatctggcaaaacagt
gatttcaacttcgacaacgtcctctctgctatgatggcactcttcacggtctccacgttt
gagggctggcctgcgttgctgtataaagccatcgactcgaatggagagaacatcggccca
atctacaaccaccgcgtggagatttccatcttcttcatcatctacatcatcattgtagct
ttcttcatgatgaacatctttgtgggctttgtcatcgttacatttcaggagcaaggagaa
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttg
aaagcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcttcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactacgagcagtccaagatgttcaatgacgccatggacatcctg
aacatggtcttcaccggggtgttcaccgtcgagatggttttgaaagtcatcgcctttaag
cctaaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagc
attatagacgtggccctcagcgaagcagacccaactgaaagtgaaaatgtccctgtccca
actgctacacctgggaactctgaagagagcaatagaatctccatcacctttttccgtctt
ttccgagtgatgcgattggtgaagcttctcagcaggggggaaggcatccggacattgctg
tggacttttattaagtcctttcaggcactcccgtatgtggccctcctcatagccatgctg
ttcttcatctatgcggtcattggcatgcagatgtttgggaaagttgccatgagagataac
aaccagatcaataggaacaataacttccagacgtttccccaggcggtgctgctgctcttc
aggtgtgcgacaggtgaggcctggcaggagatcatgctggcctgcctcccagggaagctc
tgtgaccctgagtcagattacaaccccggggaggagtatacatgtgggagcaactttgcc
attgtctatttcatcagtttttacatgctctgtgcgtttctgatcatcaatctgtttgtg
gctgtcatcatggataatttcgactatctgacccgggactggtctattttggggcctcac
catttagatgaattcaaaagaatatggtcagaatatgaccctgaggcaaagggaaggata
aaacaccttgacgtggtcactctgcttcgacgcatccagcctcccctggggtttgggaag
ttatgcccacacagagtagcgtgcaagagattagttgccatgaacatgcctctcaacagt
gacgggacagtcatgtttaatgcaaccctatttgctttggttcgaacagctcttaagatc
aagaccgaagggaacctggagcaagctaatgaagaacttcgggctgtgataaagaagatt
tggaagaaaaccagcatgaaattacttgaccaagttgtccctccagctggtgatgatgag
gtaaccgtggggaagttctatgccactttcctgatacaggactactttaggaaattcaag
aaacggaaagaacaaggactggtgggaaagtaccctgcgaagaacaccacaattgcccta
caggcgggattaaggacactgcatgacattgggccagaaatccggcgtgctatatcgtgt
gatttgcaagatgacgagcctgaggaaacaaaacgagaagaagaagatgatgtgttcaaa
agaaatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagattcc
cttcagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcaattccacct
gcaagtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccat
cataaccataattccataggaaagcaagttcccacctcaacaaatgccaatctcaataat
gccaatatgtccaaagctgcccatggaaagcggcccagcattgggaaccttgagcatgtg
tctgaaaatgggcatcattcttcccacaagcatgaccgggagcctcagagaaggtccagt
gtgaaaagaacccgctattatgaaacttacattaggtccgactcaggagatgaacagctc
ccaactatttgccgggaagacccagagatacatggctatttcagggacccccgctgcttc
ggggagcaggagtatttcagtagcgaggagtgctatgaggatgacagctcgcccacctgg
agcaggcaaaactatggctactacagcagatacccaggcagaaacgtggactttgagagg
ccccgaggctaccatcacccccaaggattcttggaggacgatgactcgcccatttgctat
gattcacggagatctccaaggagacgcctactacctcccaccccagcatcccaccgcaga
tcctccttcaacttcgagtgcctgcgccggcagagcagccaggaggaggtcccttcatct
cccaccttcccccaccgcacggccctgcctctgcatctcatgcagcaacagatcatggca
gttgctggcctagattcaagtaaagcccagaagtactcaccgagtcactcaacccggtca
tgggccacccctccagcaacccctccctaccgggactggacaccgtgctacacccccctg
atccaagtggagcagttagaggccctggaccagatgaacggcagcctgccgtccctgcac
cgcagttcctggtacacagacgagcccgacatctcctaccggactttcacaccagccagc
ctgaccgtccccagcagcttccggaacaaaaacagcgacaagcagaggagcgcggacagc
ttggtggaggcagtcctgatatctgaaggcttgggacgctatgcaagggacccaaaattt
gtgtcagcaacaaaacatgaaatcgctgatgcctgtgaccttaccatcgacgagatggag
agtgcagccagcaccctgcttaatgggaacgtgtgtccccgagccaacggggatgtgggc
cccctctcacaccggcaggactatgagctacaggactttggtcctggctacagcgacgaa
gagccagaccctgggagggatgaggaggacctggcggatgaaatgatatgcatcaccacc
ttgtag
DBGET
integrated database retrieval system
