KEGG   Mandrillus leucophaeus (drill): 105544191
Entry
105544191         CDS       T08763                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu04010  MAPK signaling pathway
mleu04015  Rap1 signaling pathway
mleu04218  Cellular senescence
mleu04380  Osteoclast differentiation
mleu04620  Toll-like receptor signaling pathway
mleu04664  Fc epsilon RI signaling pathway
mleu04668  TNF signaling pathway
mleu04750  Inflammatory mediator regulation of TRP channels
mleu04912  GnRH signaling pathway
mleu04935  Growth hormone synthesis, secretion and action
mleu04936  Alcoholic liver disease
mleu05014  Amyotrophic lateral sclerosis
mleu05022  Pathways of neurodegeneration - multiple diseases
mleu05132  Salmonella infection
mleu05135  Yersinia infection
mleu05145  Toxoplasmosis
mleu05161  Hepatitis B
mleu05163  Human cytomegalovirus infection
mleu05167  Kaposi sarcoma-associated herpesvirus infection
mleu05169  Epstein-Barr virus infection
mleu05170  Human immunodeficiency virus 1 infection
mleu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mleu05417  Lipid and atherosclerosis
mleu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105544191 (MAP2K6)
   04015 Rap1 signaling pathway
    105544191 (MAP2K6)
   04668 TNF signaling pathway
    105544191 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    105544191 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105544191 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    105544191 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105544191 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    105544191 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105544191 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105544191 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105544191 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105544191 (MAP2K6)
   05161 Hepatitis B
    105544191 (MAP2K6)
   05163 Human cytomegalovirus infection
    105544191 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105544191 (MAP2K6)
   05169 Epstein-Barr virus infection
    105544191 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105544191 (MAP2K6)
   05135 Yersinia infection
    105544191 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105544191 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105544191 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    105544191 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105544191 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    105544191 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105544191 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mleu01001]
    105544191 (MAP2K6)
Enzymes [BR:mleu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     105544191 (MAP2K6)
Protein kinases [BR:mleu01001]
 Serine/threonine kinases: STE group
  STE7 family
   105544191 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 105544191
NCBI-ProteinID: XP_011842312
Ensembl: ENSMLEG00000031299
UniProt: A0A2K5YG13
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattccaaaagaagcattt
gagcaacctcagaccagttccacaccacctcgagatttagactccaaggcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgacctggagcctataatggaactggga
cgaggtgcgtacggggtggtggagaagatgcggcacgtgcccagcgggcagatcatggca
gtgaagcggattcgagccacagtaaatagccaggaacagaaaaggctactgatggatttg
gatatttccatgaggacggtggactgtccattcaccgtcaccttttatggcgcactgttt
cgggagggtgatgtgtggatctgcatggagctcatggacacatcactagataaattctac
aaacaagttattgataaaggccagacaattccagaggacatcttagggaaaatagccgtt
tctattgtaaaagcattagaacatttacacagtaagctgtctgtcattcacagagacgtc
aagccttctaatgtactcattaatgctctcggtcaagtgaagatgtgcgattttggaatc
agtggctacttggtggactctgttgctaaaacaattgatgcgggttgcaaaccatacatg
gcccctgaaagaataaacccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcacgatgattgagttggccatccttcgatttccctatgattcctgg
ggaactccatttcagcagctcaaacaggtggtagaggagccatcgccacaactcccagca
gacaagttctctgcagagttcgttgactttacctcacagtgcttaaagaagaattccaaa
gaacggcctacatacccagagctaatgcaacatccatttttcaccctacatgaatccaaa
ggaacagatgtggcatcttttgtaaaactgattcttggagactaa

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