Mandrillus leucophaeus (drill): 105545516
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Entry
105545516 CDS
T08763
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu00562
Inositol phosphate metabolism
mleu01100
Metabolic pathways
mleu04014
Ras signaling pathway
mleu04015
Rap1 signaling pathway
mleu04020
Calcium signaling pathway
mleu04024
cAMP signaling pathway
mleu04070
Phosphatidylinositol signaling system
mleu04919
Thyroid hormone signaling pathway
mleu04933
AGE-RAGE signaling pathway in diabetic complications
mleu05205
Proteoglycans in cancer
Module
mleu_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
105545516 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
105545516 (PLCE1)
04015 Rap1 signaling pathway
105545516 (PLCE1)
04020 Calcium signaling pathway
105545516 (PLCE1)
04070 Phosphatidylinositol signaling system
105545516 (PLCE1)
04024 cAMP signaling pathway
105545516 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
105545516 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
105545516 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
105545516 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mleu04131
]
105545516 (PLCE1)
Enzymes [BR:
mleu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
105545516 (PLCE1)
Membrane trafficking [BR:
mleu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
105545516 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
105545516 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
105545516
NCBI-ProteinID:
XP_011843850
Ensembl:
ENSMLEG00000012552
UniProt:
A0A2K5XI52
LinkDB
All DBs
Position
Unknown
AA seq
2303 aa
AA seq
DB search
MTSEEITASVLIPVTQRKVVSAQSAADESSEKVSDINISKARTVRQSGETSHTISRLNKL
KEEPSGSNLPNFLSITREKIVSDENSNEKCWEKSMPDSVKNLNINCNNILRNHQHGLPQR
QFYEMYNSVVEEDLCLETGILSPLERKVFPGIQLELDRPSMGINPLGNQSAIIETGRADP
DSSTAVFHFHYEVDRRMSDTFCTLSENLILDDCGNCVPLPGGEEKQKENYVAYTCKLMEL
AKNCDNKNEQLQCDHCDTLNDKYFCFEGSCQKVDMVYSSHSFCKEDFTDSQTAKTFLSHF
EDFPDNCEDVEEDAFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLIA
WSYIDQKRNGPLLPCGRVMEPLSTVEIKQGGSRRLSEAQWYPIYNAVRRGEETENTVGSL
LHFFTKLPASETAHGRISVGPCLKQCVRDTVYEYRATLQRTSISQYITGSLLEATTSLGA
RSGLLSTFGGSTGRMMLKERQPGPSVANSNTLPSSSAGISKELIDLQPLIQFPEEVASIL
MEQEQSIYRRVLPVDYLCFLTRDLGTPECQRSLPCLKASISASILTTQNGEHNALEDLVM
RFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM
WQFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDG
ASGLMKICPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKETTVNSIFQVIRSCSR
SLETDEEDSPSEGNSSRKSSLKDKSRWQFIIGDLLDSDNDIFEQSKEYDSHGLEDSQKAF
DHGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTA
SPASTKAKLGVLNNTAEPGKFPLLGNAGLSGLTEGVLDLFAVKAVFMGHPGIDIHTVCVQ
NKLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQR
QQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPSMQRNNTL
GISTTKKKKKILMRGESGEATDDEMATRKAKMHKECRSRSGSDPQDINEQEESEANTIAS
PPNPLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLPSSNKSPSSAWSSSSWHGRIKGG
MKGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCSRSGSESAPLYTNLM
IDENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSL
GIFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPNISMCHQGLMSFEGFARFLMDKEN
FASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELD
CWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAE
IFKTVFGEKLVAKFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQL
ASMQAQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEY
SEEIPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPG
LSTLNASGSNRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPL
NPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNP
NPIMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPL
ERDLDSMDPVVYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPM
WNEQFLFRVHFEDLVFLRFAVVENNSSVVTAQRIIPLKALKRGYRHLQLRNLHNEVLEIS
SLFINSRRMEENSSGSTMSASSMFNTEERKCLQTHRVTVHGVPGPEPFTVFTINGGTKAK
QLLQQILTTEQGIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILSSWFP
EEGYVGRIVLKTQQENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVS
TAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKSTTPKSSQRVLLDQECVF
QAQSKWKGAGKFILKLKEQVQASREDKKKSISFASELKKLTKSTKQPRGLTSPSQLLTSE
SIQTKEEKPVGGLSSSDTMDYRQ
NT seq
6912 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaattacagcttctgttctcatacctgtgactcagagaaaagtggtt
tctgcccagtcagctgcagatgaaagtagtgaaaaggtctcagacatcaatatttcaaaa
gcacgtactgtcagacaaagtggggagacttctcataccatctcacgactgaacaaactt
aaagaagaaccttctggaagcaacttgccaaattttctctcaataacaagggagaaaata
gtgagtgatgagaacagtaatgaaaaatgctgggagaaaagcatgccagattctgtgaaa
aaccttaacattaactgcaacaacatattgagaaaccatcagcatggccttcctcaaaga
cagttttatgaaatgtacaactctgttgttgaggaagacctgtgtttagaaactggaatt
ctgtctccactggaaagaaaggtgttccctggaattcaactggaactagacagaccttcc
atgggcattaatcctttaggaaatcagtcagcaatcatagagacaggcagagcagaccct
gacagcagcacggcagtatttcattttcattatgaagttgacagaagaatgtcagacact
ttctgtaccctatcagaaaacttaattttagacgattgtggaaattgtgtaccactacct
gggggtgaggagaagcaaaaggaaaactacgtggcatatacgtgtaaactgatggaattg
gccaaaaattgtgataataagaatgaacagctgcagtgtgatcattgtgacaccttgaat
gataaatacttttgctttgaaggctcttgccagaaggtggacatggtatattcaagtcat
agcttttgtaaggaagattttactgacagtcaaactgccaagacctttttgagccatttt
gaggacttccctgataattgtgaagacgtagaagaagatgcttttaaaagcaaaaaggag
cggtccactttgttagtcaggagattctgtaaaaatgacagagaagttaagaaatctgtg
tataccggaacaagagcaattgtgaggactctgccttctggccacattgggctgattgca
tggagttacatagatcagaagagaaatggtcccttactgccttgtgggagagtaatggaa
cccctatcaacagtggagataaagcaaggtgggagccgacgtctgtcagaagcccagtgg
tatcctatctacaatgcagtgagaagaggagaagaaacagaaaatacagttggatctcta
ctccatttcttcaccaagctcccagcctccgagacagcccatggaagaataagtgttggt
ccatgcttaaagcaatgtgtccgagacactgtatatgagtatcgcgccaccctccaaagg
acttcaatatcgcagtacatcaccggttctctcctagaagcaaccacatctttgggagca
agaagtggccttctcagtacttttggaggatccactggacgaatgatgctgaaagaacgc
cagccaggcccctctgtggccaattccaacaccctcccttcaagttcagctgggatcagc
aaggagctgatcgatctgcagcctctcatccagttcccagaggaagtcgccagcatcctg
atggagcaggagcagagtatttaccgcagggtcttgccagttgactacctttgcttctta
acacgggacttgggcactcctgaatgccaaaggtccctgccctgcctcaaagcatccatc
tcagcgtcgattcttaccactcagaatggagagcacaatgcccttgaagatctggtgatg
aggtttaatgaggtgagctcctgggtgacgtggctgatcctcacggcaggctccatggag
gagaagcgagaagtcttttcatatttggtgcatgtggccaagtgctgctggaacatgggc
aactacaacgctgtcatggagttcttggctggcctcaggtcaagaaaagttttaaaaatg
tggcagtttatggaccagtctgatattgagaccatgaggagcctgaaggatgctatggcc
cagcatgagtcctcttgtgagtacagaaaggtggtgacacgtgccctgcacatccctggc
tgtaaggtggttccgttctgtggagtgtttctgaaggagctctgtgaagtgcttgacggc
gcctctggcctcatgaagatatgcccgcggtacaattcccaagaagaaactttagagttt
gtagcagattacagtggacaagataatttcttacaacgagtgggacaaaatggcttaaag
aattcggagaaggagaccactgtcaacagcatctttcaggtcatccggagctgcagtcga
agtctggagacagacgaggaggacagccccagtgaagggaacagctccaggaaaagttcc
ttgaaggataaaagccgatggcagtttataattggagatttgttggattcagacaatgat
atctttgagcaatccaaagaatatgactctcatggtttagaggactcacagaaggccttc
gaccatggaacggagctcatcccatggtatgtgctgtccatccaagccgatgtgcaccag
ttcctgctgcagggtgccacggtcatccactacgaccaggacacacacctctctgcccgc
tgcttcctccagcttcagcctgacaatagcaccttgacctgggtaaagcccacaactgcc
tccccagccagcactaaagcaaaacttggtgtacttaataacacagctgagcctggaaaa
ttcccactactgggcaatgctggattaagtggcctgacggaaggggtcttggatcttttt
gcagtgaaggctgtattcatgggccaccctggcattgatatacacactgtgtgtgttcag
aacaaactgggtagcatgttcctgtcagagactggtgtgacactgctctatgggcttcag
accacggacaatagattattgcacttcgtggcaccaaagcacacagctaaaatgctcttc
agcggattgttggaactcactagagctgtgagaaagatgaggaaattccctgaccaaaga
cagcagtggctgcggaaacagtacgtcagcctctatcaggaggatggacggtatgaaggc
ccaactttggctcatgctgtggagttgtttggtggcagacgatggagtgctcgaaacccc
agccccggcacatctgcaaagaatgctgagaagcccagtatgcagagaaacaacaccctg
ggcataagcactaccaagaaaaagaagaaaatcctcatgaggggtgagagtggagaggca
actgacgatgagatggcaacccgaaaggccaagatgcacaaagagtgtcgaagccggagt
ggttctgatcctcaagacattaatgaacaagaagaatcagaggcgaataccatcgctagc
ccgccaaaccccctcccttccagaagagcccactctttgaccacagctgggtcccccaac
ttggctgccgggacgtcatctcccatcaggccagtgtcctcccctgtgctgccttcttca
aacaagagcccgtccagtgcttggagcagtagtagctggcacgggcggatcaaaggcggc
atgaagggatttcagagcttcatggtttcagacagcaacatgagttttgttgaatttgtt
gagctgttcaaatcgttcagtgtcaggagccgcaaggacctgaaggatctgtttgatgtc
tatgcagtgccctgcagccgatctggatccgagtcagccccgctctacaccaacttgatg
attgatgaaaacaccagcgatcttcagcctgacctagatctgttgaccagaaatgtctca
gatttggggttgttcatcaagagtaaacagcagctatcggacaaccagaggcagatatct
gatgccattgctgctgcaagcatcgtgacaaatggcactgggattgagagcacatctctg
ggcattttcggggtaggcatacttcagctcaacgatttcctcgtgaattgccaaggagaa
cactgcacttatgatgaaatcctcagcatcatccagaagtttgagcctaacatcagtatg
tgtcatcagggactaatgtcatttgaagggtttgcaaggtttctgatggataaagaaaat
tttgcctcaaaaaacgatgagtcacaggagaacattaaagaactgcagctacccctctca
tactattacatcgaatcatcgcacaatacctacctcacgggccatcagctcaaaggagaa
tcctcggtagaactctacagccaggtcctcttgcaaggctgtcgaagtgtagaattggac
tgctgggacggagacgatgggatgcccatcatttatcatggacatacactgacaaccaag
atccccttcaaggaagtggttgaagccattgatcgcagtgcgttcatcaactctgacctg
ccaatcatcatatcaattgagaaccactgttcattgcctcagcaacgaaaaatggcagaa
attttcaagactgtgtttggagaaaagctggtggctaaattcttatttgagactgatttc
tcagatgatccaatgcttccttcacctgaccaactcagaaggaaagtgcttcttaaaaac
aagaaactaaaagcccatcagacgccagtggatatcttaaagcaaaaggctcatcagtta
gcatctatgcaagcgcaggcttataatggtgggaatgccaaccccccacctgccaataat
gaggaagaggaagatgaggaggacgaatatgattatgactatgaatccctttctgatgac
aacattctggaagacagacctgaaaataaatcatgtaatgacaagcttcagtttgagtat
agtgaagaaatccccaagaggataaagaaggcagataactctgcttgcaacaaaggaaag
gtttatgatatggaactgggagaagaattttatcttgatcagaataaaaaggaaagcaga
cagattgcaccagagctttctgaccttgtaatctattgtcaagcagtaaaatttccagga
ctgtcaactctaaatgcatctggctctaacagaggaaaggaaaggaaaagcaggaagtcc
atttttggcaacaatccgggcagaatgagcccaggggagacagcatcatttaacaaaaca
tctggaaaaagttcctgtgaaggcattcgacagacctgggaggaatcttcttcccctctc
aacccaaccacgtccctcagtgctatcattagaactcctaaatgttatcatatctcgtcg
ctgaatgaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcac
accgcctgtcagctgctgagaacttaccctgctgccacccgcatcgactcctccaacccg
aaccccatcatgttctggctccatgggatacagctcgtggcactcaactaccagaccgat
gatctccctttacatttaaatgctgcaatgtttgaggcaaatggtggttgtggttatgtt
ttgaaacctccggttctgtgggacaagaactgcccgatgtatcagaagttttctccactg
gaaagagatctggacagcatggatcctgtagtctattctttaactattgtctctggtcag
aatgtgtgccccagtaacagcacgggaagcccgtgcattgaagtcgatgtcctgggcatg
cctctggacagctgccatttccgcacgaagcccatccatcgaaacaccctgaaccccatg
tggaacgagcagtttctgttccgcgttcacttcgaagatctcgtatttcttcgttttgca
gttgtggaaaacaacagttcagtggtaactgctcagagaatcattccactgaaagcttta
aaacgaggctatcgacatcttcagctgcgaaaccttcacaatgaagtcttggaaatctct
agtttattcattaacagcagaaggatggaagaaaattcctctggcagtaccatgtcagcc
tcttcgatgtttaatacagaagaaagaaaatgtttgcagactcacagagtcacggtgcat
ggggtcccagggccagagccctttactgttttcactattaatggaggcaccaaggcaaag
cagcttctgcagcaaattctgacaactgaacaaggcatcaaacctgttaccacagactat
tttttgatggaagaaaaatattttatatctaaagaaaagaatgaatgcaggaaacaacca
ttccagagagccattggtccagaagaggagatcgtgcaaattttaagcagctggtttcca
gaagagggatatgtgggcaggattgtcttaaaaacccagcaggaaaacctagaagagaaa
aacattgttcaagatgacaaagaggtgatcttgagctcagaggaggagagtttctttgtc
caagtgcatgatgtttctccagagcaacctcgaacagtcatcaaagcaccccgcgtcagc
accgcacaggatgtcattcagcagaccttatgcaaagccaaatattcctacagcatcctg
agcaaccccaatccgagtgactatgtgcttctggaagaggtggtgaaagacactaccaac
aagaagtctaccacacccaagtcctctcagcgggtccttctggatcaggagtgtgtgttt
caagcccaaagcaagtggaaaggtgcaggaaaattcatccttaagctaaaggagcaggtg
caggcatctcgagaagacaaaaagaaaagcatttcttttgcaagtgaactcaagaagctc
accaagtcaactaaacagccccgaggacttacatcaccttctcagctcttgacctcagaa
agtatccaaaccaaggaggagaaacctgtgggtggcttgtcctccagtgacacaatggat
taccgacagtga
DBGET
integrated database retrieval system
