KEGG   Mandrillus leucophaeus (drill): 105545564
Entry
105545564         CDS       T08763                                 
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu00260  Glycine, serine and threonine metabolism
mleu00630  Glyoxylate and dicarboxylate metabolism
mleu00670  One carbon pool by folate
mleu01100  Metabolic pathways
mleu01200  Carbon metabolism
mleu01230  Biosynthesis of amino acids
mleu01240  Biosynthesis of cofactors
mleu01523  Antifolate resistance
mleu04981  Folate transport and metabolism
Module
mleu_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    105545564 (SHMT2)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    105545564 (SHMT2)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    105545564 (SHMT2)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    105545564 (SHMT2)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    105545564 (SHMT2)
Enzymes [BR:mleu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     105545564 (SHMT2)
SSDB
Motif
Pfam: SHMT
Other DBs
NCBI-GeneID: 105545564
NCBI-ProteinID: XP_011843927
Ensembl: ENSMLEG00000031792
LinkDB
Position
Unknown
AA seq 513 aa
MSGVLGLASQAEPFRPALSPADDATEPHCLHQTGVPAAVRAGRRWNGLCRDGGSWSGWPF
GLSTARQPRLRLGKQTGAGQARRACRTAILRCGSCCRGRRTGSVVAWSSLPQRYYGGAEV
VDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGH
LTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARL
IDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIF
YRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYS
LQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNT
CPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKTKTGKLQDFKSF
LLKDSETSQRLADLRQRVEQFARGFPMPGFDEH
NT seq 1542 nt   +upstreamnt  +downstreamnt
atgagtggagttctcggcctggcctcacaagctgagccttttcggccagctctgagccct
gcagatgatgcaaccgagcctcactgcttgcatcagacaggggtcccggcggcagtgagg
gctggaaggaggtggaacggcctctgcagagatgggggcagctggtcaggatggccattc
gggctcagcacagcaaggcagcccagactcagactggggaagcaaacaggggctggacag
gccaggagagcctgtcggacagcgatcctgagatgtgggagttgctgcagagggagaagg
acaggcagtgtcgtggcctggagctcattgcctcagagatattatgggggagcagaggtg
gtggatgaaattgagctgctgtgccagcgccgggccttggaagcctttgacctggatcct
gcacagtggggagtcaatgtccagccctactctgggtccccagccaacctggctgtctat
acagcccttctgcaacctcatgaccggatcatggggctggacctgcccgatgggggccat
ctcacccacggctacatgtctgacgtcaagcggatatcagccacgtccatcttcttcgag
tctatgccctataagctcaatcccaaaactggcctcattgactatgaccagctggcactg
actgctcgacttttccgaccgcggctcatcatagctggcaccagcgcctatgctcgcctc
attgactatgcccgcatgagagaggtgtgtgatgaagtcaaagcacacctactggcagac
atggctcacatcagtggcctggtggctgccaaggtgattccctcgcctttcaagcacgcg
gacatcgtcaccaccactactcacaagactcttcgaggggccaggtcagggctcatcttt
taccggaaaggggtgaaggctgtggaccccaagactggccgggagatcccttacacattt
gaggaccgaatcaactttgctgtgttcccatccctgcaggggggcccccacaatcatgcc
attgctgcagtagctgtggccctaaagcaggcttgcacccccatgttccgggagtactcc
ctgcaggttctgaagaatgctcgggccatggcggatgccctgctagagcgaggctactca
ctagtatcaggtggtactgacaatcacctggtgctggtggacctgcggcccaagggcctg
gatggagctcgggctgagcgggtgctggagcttgtatccatcactgccaacaagaacacc
tgtcctggagaccgaagtgccatcacaccggggggcctgcggcttggggccccggccttg
acttctcgacagttccgtgaggatgacttccggagagttgtggactttatagatgaaggg
gtcaacattggcttagaggtgaagaccaagactggcaagctccaagatttcaaatccttc
ctgctcaaggactcagaaacaagtcagcgtctggccgacctcaggcaacgggtggagcag
tttgccaggggcttccccatgcctggttttgatgagcattga

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