KEGG   Mandrillus leucophaeus (drill): 105549398
Entry
105549398         CDS       T08763                                 
Symbol
NDUFS1
Name
(RefSeq) LOW QUALITY PROTEIN: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
  KO
K03934  NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu00190  Oxidative phosphorylation
mleu01100  Metabolic pathways
mleu04714  Thermogenesis
mleu04723  Retrograde endocannabinoid signaling
mleu04932  Non-alcoholic fatty liver disease
mleu05010  Alzheimer disease
mleu05012  Parkinson disease
mleu05014  Amyotrophic lateral sclerosis
mleu05016  Huntington disease
mleu05020  Prion disease
mleu05022  Pathways of neurodegeneration - multiple diseases
mleu05208  Chemical carcinogenesis - reactive oxygen species
mleu05415  Diabetic cardiomyopathy
Module
mleu_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    105549398 (NDUFS1)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    105549398 (NDUFS1)
  09159 Environmental adaptation
   04714 Thermogenesis
    105549398 (NDUFS1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    105549398 (NDUFS1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105549398 (NDUFS1)
   05012 Parkinson disease
    105549398 (NDUFS1)
   05014 Amyotrophic lateral sclerosis
    105549398 (NDUFS1)
   05016 Huntington disease
    105549398 (NDUFS1)
   05020 Prion disease
    105549398 (NDUFS1)
   05022 Pathways of neurodegeneration - multiple diseases
    105549398 (NDUFS1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    105549398 (NDUFS1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    105549398 (NDUFS1)
Enzymes [BR:mleu01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     105549398 (NDUFS1)
SSDB
Motif
Pfam: Molybdopterin Fer4_Nqo3 Fer4_NDSU1 Fer2_4 NADH-G_4Fe-4S_3 NADH_dhqG_C Fer2
Other DBs
NCBI-GeneID: 105549398
NCBI-ProteinID: XP_011849307
LinkDB
Position
Unknown
AA seq 675 aa
MRIRGPSGALARINMLRIPVRKALVGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPG
TTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNS
EKSRKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGNDRSRFLEGKRAVEDKNIG
PLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDIC
PVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWI
SDKTRFAYDGLKRQRLTEPMIRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAIAGGLV
DAEALVALKDLLNRVDSDTLCTEEVFPTAGAGXEIRIFVLQSYYGLKQRLKIVLKEAKKP
MVVLGSSALQRNDGAAILAAVSSIAQKIRMTSGVTGDWKVMNILHRIASQVAALDLGYKP
GVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEK
SATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPN
LVRYDDIEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVK
AVTEGAQAVEEPSIC
NT seq 2028 nt   +upstreamnt  +downstreamnt
atgaggatcagggggccctcgggagcgctggcccgaatcaatatgttgaggatacctgta
agaaaggccttagtaggcctttctaaatctcctaaaggatgtgttcgaacaactgccaca
gcagcaagcaacttgattgaagtatttgttgatggtcagtctgtcatggtggaaccggga
acgaccgtcctccaagcttgtgagaaggttggcatgcagatccctcgattctgttatcat
gaaaggttgtctgttgctggaaactgcaggatgtgccttgttgaaattgagaaagccccc
aaggttgtagctgcttgtgccatgccagtaatgaagggctggaatatcctaacaaactca
gaaaaatccaggaaagccagggaaggtgtgatggagttcttattagcaaatcacccactg
gactgtcctatttgtgaccagggaggtgaatgtgatctgcaggaccagtccatgatgttt
ggaaatgataggagccgatttttagaggggaagcgtgctgtggaagacaagaacattggg
ccattggtaaagaccatcatgacaagatgtatacagtgtactcgctgcatcaggtttgca
agtgagattgcaggagtagatgatttgggaacaacaggcagaggaaatgatatgcaagtt
ggcacatacattgaaaagatgttcatgtctgaactgtctgggaatatcattgatatctgc
cctgtaggtgccctaacctctaagccctatgcctttactgcccggccttgggaaacaaga
aagacagaatccattgatgtaatggatgcagttggaagtaatattgtggttagcacaaga
actggagaagtgatgaggattttgccacgtatgcatgaggacatcaatgaagagtggatc
tctgataaaaccagatttgcctatgatgggctaaaacgtcaaagacttaccgagccgatg
atcagaaatgaaaaagggcttttaacctatacttcttgggaggatgcactctctcgtgta
gctggaatgttgcagagttttcaaggcaaagatgtggcagcaattgcaggtggcttggtg
gatgctgaagccctagtagctctcaaagatttacttaatagagtggactctgacacctta
tgcactgaagaggtcttccccactgcaggagctgggtgagaaatacgaatttttgtcctt
cagagttactatggtttaaaacaaaggcttaaaattgtcctaaaggaggctaaaaaacca
atggtggttttaggcagttctgcactccaaagaaatgatggagcagcaattcttgcagct
gtctctagcattgcacaaaagattcggatgactagtggtgttactggcgattggaaagtt
atgaatatccttcataggattgcaagtcaagtagctgctttggaccttggctataaacct
ggggtggaagcaattcggaagaaccctcccaaggtgctgtttctcctgggagcagatgga
ggctgtatcacacgacaggatttgccaaaggattgtttcattatttatcaaggacatcat
ggtgatgttggggctcccatagctgatgttattctcccaggagctgcttacacagagaag
tctgctacatatgtcaacactgagggtagagctcagcagactaaggtagcagtgacacct
cctggcttggcaagagaagactggaaaattataagagcactctctgagattgctggaata
actcttccatatgatactctggatcaagtaaggaacagattggaagaagtctctcctaat
cttgttcgatatgatgatattgaaggggctaattacttccagcaagcaaatgagctctca
aagctagtgaaccagcagcttcttgctgacccacttgttccacctcagctaactataaaa
gacttctacatgacagattcaattagcagagcctcacagacaatggccaaatgtgtcaaa
gctgtcacagagggtgcccaggcagtagaggaaccatccatatgctga

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