KEGG   Mandrillus leucophaeus (drill): 105549624
Entry
105549624         CDS       T08763                                 
Symbol
EIF2S1
Name
(RefSeq) eukaryotic translation initiation factor 2 subunit 1
  KO
K03237  translation initiation factor 2 subunit 1
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu04137  Mitophagy - animal
mleu04140  Autophagy - animal
mleu04141  Protein processing in endoplasmic reticulum
mleu04156  Integrated stress response (ISR) signaling pathway
mleu04210  Apoptosis
mleu04932  Non-alcoholic fatty liver disease
mleu05010  Alzheimer disease
mleu05012  Parkinson disease
mleu05014  Amyotrophic lateral sclerosis
mleu05020  Prion disease
mleu05022  Pathways of neurodegeneration - multiple diseases
mleu05160  Hepatitis C
mleu05162  Measles
mleu05164  Influenza A
mleu05168  Herpes simplex virus 1 infection
mleu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    105549624 (EIF2S1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105549624 (EIF2S1)
   04137 Mitophagy - animal
    105549624 (EIF2S1)
  09143 Cell growth and death
   04210 Apoptosis
    105549624 (EIF2S1)
   04156 Integrated stress response (ISR) signaling pathway
    105549624 (EIF2S1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    105549624 (EIF2S1)
   05164 Influenza A
    105549624 (EIF2S1)
   05162 Measles
    105549624 (EIF2S1)
   05168 Herpes simplex virus 1 infection
    105549624 (EIF2S1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105549624 (EIF2S1)
   05012 Parkinson disease
    105549624 (EIF2S1)
   05014 Amyotrophic lateral sclerosis
    105549624 (EIF2S1)
   05020 Prion disease
    105549624 (EIF2S1)
   05022 Pathways of neurodegeneration - multiple diseases
    105549624 (EIF2S1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105549624 (EIF2S1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    105549624 (EIF2S1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:mleu03012]
    105549624 (EIF2S1)
   04131 Membrane trafficking [BR:mleu04131]
    105549624 (EIF2S1)
Translation factors [BR:mleu03012]
 Eukaryotic type
  Initiation factors
   eIF-2
    105549624 (EIF2S1)
Membrane trafficking [BR:mleu04131]
 Autophagy
  ER-phagy
   ER stress-related proteins
    105549624 (EIF2S1)
SSDB
Motif
Pfam: EIF_2_alpha S1
Other DBs
NCBI-GeneID: 105549624
NCBI-ProteinID: XP_011849624
Ensembl: ENSMLEG00000041672
UniProt: A0A2K6A4S2
LinkDB
Position
Unknown
AA seq 315 aa
MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN
KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE
YTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNI
NRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTT
TLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEV
DGDDDAEEMEAKAED
NT seq 948 nt   +upstreamnt  +downstreamnt
atgccgggtctaagttgtagattttatcaacacaaatttcctgaggtggaagatgtagtg
atggtgaatgtcagatccattgctgaaatgggggcttatgtcagcttgctggaatacaac
aacattgaaggcatgattcttcttagtgaattatccagaaggcgtatccgttctatcaac
aaactcatccgaattggcaggaatgagtgtgtggttgtcattagggtggacaaagaaaaa
ggatatattgatttgtcaaaaagaagagtttctccagaggaagcaatcaaatgtgaagac
aaattcacaaaatcgaaaactgtttatagcattcttcgtcatgttgctgaggtgttagaa
tacaccaaggatgagcagctggaaagcctattccagaggactgcctgggtctttgatgac
aagtacaagagacctggatatggtgcctatgatgcatttaagcatgcagtctcagaccca
tctattttggatagtttagatttgaatgaagatgaacgggaagtactcattaataatatt
aataggcgcttaaccccacaggctgtcaaaattcgagcagatattgaagtggcttgttat
ggttatgaaggcattgatgctgtaaaagaagccctaagagcaggtttgaattgttctaca
gaaaacatgcccattaagattaatctaatagctcctcctcggtatgtaatgactacgaca
accctggagagaacagaaggcctttctgtcctcagtcaagctatggctgttatcaaagaa
aagattgaggaaaagaggggtgtgttcaatgttcaaatggagcccaaagtggtcacagat
acagatgagactgaacttgcgaggcagatggagaggcttgaaagagaaaatgccgaagtg
gatggagatgatgatgcagaagaaatggaagccaaagctgaagattaa

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