Mandrillus leucophaeus (drill): 105549798
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Entry
105549798 CDS
T08763
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu04217
Necroptosis
mleu04380
Osteoclast differentiation
mleu04620
Toll-like receptor signaling pathway
mleu04621
NOD-like receptor signaling pathway
mleu04630
JAK-STAT signaling pathway
mleu04658
Th1 and Th2 cell differentiation
mleu04659
Th17 cell differentiation
mleu05145
Toxoplasmosis
mleu05160
Hepatitis C
mleu05161
Hepatitis B
mleu05162
Measles
mleu05164
Influenza A
mleu05165
Human papillomavirus infection
mleu05167
Kaposi sarcoma-associated herpesvirus infection
mleu05168
Herpes simplex virus 1 infection
mleu05169
Epstein-Barr virus infection
mleu05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
105549798 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
105549798 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
105549798 (TYK2)
04621 NOD-like receptor signaling pathway
105549798 (TYK2)
04658 Th1 and Th2 cell differentiation
105549798 (TYK2)
04659 Th17 cell differentiation
105549798 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
105549798 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
105549798 (TYK2)
05160 Hepatitis C
105549798 (TYK2)
05171 Coronavirus disease - COVID-19
105549798 (TYK2)
05164 Influenza A
105549798 (TYK2)
05162 Measles
105549798 (TYK2)
05168 Herpes simplex virus 1 infection
105549798 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
105549798 (TYK2)
05169 Epstein-Barr virus infection
105549798 (TYK2)
05165 Human papillomavirus infection
105549798 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
105549798 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mleu01001
]
105549798 (TYK2)
Enzymes [BR:
mleu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
105549798 (TYK2)
Protein kinases [BR:
mleu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
105549798 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
105549798
NCBI-ProteinID:
XP_011849840
Ensembl:
ENSMLEG00000028554
UniProt:
A0A2K5XZM0
LinkDB
All DBs
Position
Unknown
AA seq
1187 aa
AA seq
DB search
MPLRHRGTTRGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI
AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRMRFYFRNWHGMNPQEP
AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHFK
NESLGMAFLHLCHLALRRGVPLEEVAKKTSFKDCIPLSFRRQIRQHSALTRLRLRNVFRR
FLQDFQPDRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGEAP
TDPGPESAAGPPTHEVLVTGTGGIQWWPVQEEVNKEEGSSGGSGRNPQASLSGKKAKAHK
AIGQPADRLREPLWAYFCDFRDITHVVLKECCVSIHRQDNKCLELSLPSRAAALSFVSLV
DGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVQAKLRPEDGLYLIQWSTSHP
YRLILTVAQCSQAPDGTQSLRLRKFPIEQQAGAFVLEGWGRSFPSVRELGAALQGCLLRA
GDDCFSLRRCCLPQPGETSNLIIMRGARASTRTLNLSQLSFHRVDQKEITQLSHLGQGTR
TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS
LMSQVSHVHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS
ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWMA
PECLPGGPNSLSIAMDKWGFGATLLEICFDGEAPLQSRSSSEKEHFYQRQHRLPEPSCPE
LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLIVNPDSSASDPTVFHKRYLKKI
RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIEILRTLYHEHIV
KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYI
HRDLAARNVLLDNDKLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY
ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGITQGQMTVLRLTELLERGERLPRPDKC
PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC
NT seq
3564 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgcgccatcgggggacgaccaggggcagcaagcccgttggggatggagcccag
cccatggctgccatgggaggcctgaaggtgcttctgcactgggctggtccaggcggcgga
gagccctgggtcacttttagcgagtcatcgctgacagctgaggaagtctgcatccacatc
gcacataaagtcggtatcactcctccttgtttcaatctcttcgccctcttcgatgctcag
gcccaagtctggttgcccccaaaccacatcctagagatccccagagacgcaagcctgatg
ctgtatttccgcatgaggttttatttccggaactggcatggcatgaatcctcaggagccg
gctgtgtaccgttgtgggcccccaggaaccgaggcatcctcagatcagacagcacagggg
atgcaacttctggacccagcctcatttgagtacctctttgagcagggcaagcatgagttt
gtgaatgacgtggcatcactgtgggagctatcgagcgaggaggagatccaccactttaag
aatgagagcctgggcatggcctttctgcacctctgtcacctcgctctccgccgtggtgtc
cccctggaggaggtggccaagaagaccagcttcaaggactgtatcccgctctccttccgt
cggcagatccggcagcacagcgccctgacccggctgcgccttcggaacgtcttccgcagg
ttcctgcaggacttccagccggacagactctcccagcagatggtcatggtcaaatacctg
gccacactcgaacggctggcaccccgctttggcacagagcgtgtgcccgtgtgccacctg
aggctgctggcccaggcagagggggagccctgctacatccgggacagtggagaggcccct
acagaccctggccctgagtctgctgctggacccccaacccatgaggtgctggtgacaggc
actggtggcatccagtggtggccagtacaggaggaggtgaacaaggaggagggttctagt
ggcggcagcggcaggaacccccaagccagcctgtctgggaagaaggccaaggctcacaag
gcaatcggccagccggcggacaggctgcgggagccactgtgggcctacttctgcgacttc
cgggacatcacccacgtggtgctgaaagagtgctgtgtcagcatccaccggcaggacaac
aagtgtctggagctgagcctgccttcccgggctgcggcgctgtccttcgtgtcgctggtg
gacggctatttccgcctgacggccgactccagccactacctgtgccacgaggtggctccc
ccacggctggtgatgagcatccaggatgggatccacggacccctgctggagccgtttgtg
caggccaagctgcggcccgaggacggcctgtacctcattcagtggagcaccagccacccc
taccgcctgatcctcacagtggcccagtgtagccaggcaccagacggcacacagagcttg
cggctccggaagttccccattgaacagcaggccggggcctttgtgctggagggctggggc
cggtccttccccagcgttcgggaacttggggccgccttgcagggctgcttgctgagggcc
ggggacgactgcttctctctgcgtcgctgttgcctgccccaaccaggagaaacctccaac
ctcatcatcatgcggggggctcgggccagcaccaggacactcaacctcagccagctcagc
ttccaccgggttgaccagaaggagatcacccagctgtcccacttgggccagggcacaagg
accaacgtgtacgagggccgcctgcgagtggagggcagtggggaccctgaggagggcaag
atggacgacgaggaccccctcgtgccaggaagggaccgtgggcaggagctacgagtggtg
ctcaaagtgctggacccgagtcaccatgacatcgccctggccttctatgagacagccagc
ctcatgagccaggtctcccacgtgcacctggccttcgtgcacggcgtctgtgtgcgcggc
cctgaaaatatcatggtgacagagtacgtggagcacggacccctggacgtgtggctgcgg
agggagcggggccatgtgcccatggcttggaagatggtggtggcccagcagctagccagc
gccctcagctacctggagaacaagaacctggtacatggtaatgtgtgtggccggaacatc
ctgctggctcggctggggctggcagagggcacgagccccttcatcaagctgagtgatccc
ggcgtgggcctcggcgccctctccagggaggagcgagtggagcggatcccctggatggcc
cccgaatgcctcccaggtgggcccaacagcctaagcattgccatggacaagtgggggttt
ggtgccaccctcctggagatctgctttgatggcgaggccccactgcagagccgcagctcc
tccgagaaggagcatttctaccagaggcagcaccggctgcccgagccctcctgcccagag
ctggccacactcaccagccagtgtctgacctatgagccaacccagaggccttcattccgc
accatcctgcgtgacctcacccggctgcagccccacaatcttgctgatgtcttgattgtg
aacccggactcatcggcgtcagaccctacggttttccacaagcgctatttgaaaaagatc
cgagatctgggcgagggtcacttcggcaaggtcagtttgtactgctacgatccgaccaac
gacggcactggcgagatggtggcggtgaaagcccttaaggcagactgcggcccccagcac
cgctcgggctggaagcaggagattgagattctgcgcacgctctatcacgagcacatcgtc
aagtacaagggctgctgcgaggaccaaggcgagaagtcgctgcagctggtcatggagtac
gtgcccctgggcagcctccgagactacctgccccggcacagcgtcgggctggcccagctg
ctgctcttcgcccagcagatctgcgagggcatggcctatctgcacgcgcagcactacatc
caccgagacctagccgcgcgcaacgtgctgctggacaacgacaagctggtcaagatcggg
gactttggcctagccaaggccgtgcccgaaggccacgagtactaccgcgtgcgcgaggat
ggggacagccccgtgttctggtatgccccagagtgcctgaaagagtataagttctactat
gcgtccgatgtctggtccttcggggtgaccctgtatgagctgctgacgcactgtgactcc
agccagagcccccccacgaaattccttgagctcataggcatcacccagggtcagatgaca
gttctgagactcaccgagttgctggaacgaggggagaggctgccacgacccgacaaatgt
ccctgtgaggtctatcatctcatgaagaactgctgggagacagaggcgtccttccgccca
actttcgagaacctcatacccatcctgaagacagtccatgagaagtaccaaggccaggcc
ccttccgtgttcagtgtgtgctga
DBGET
integrated database retrieval system
