Mandrillus leucophaeus (drill): 105551275
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Entry
105551275 CDS
T08763
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu00230
Purine metabolism
mleu01100
Metabolic pathways
mleu04927
Cortisol synthesis and secretion
mleu04934
Cushing syndrome
mleu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
105551275 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
105551275 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
105551275 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
105551275 (PDE8A)
Enzymes [BR:
mleu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
105551275 (PDE8A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS
PAS_9
PDE8_3rd
PAS_4
PAS_3
PAS_8
DUF5894
Sina_ZnF
Motif
Other DBs
NCBI-GeneID:
105551275
NCBI-ProteinID:
XP_011851841
Ensembl:
ENSMLEG00000041431
LinkDB
All DBs
Position
Unknown
AA seq
757 aa
AA seq
DB search
MRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACFLDKHHDIIIIDH
RNPRQLDAEALCRSIRSSKLSENTVIVGVVRRVDREELSVMPFIAAGFTRRYVENPNIMA
CYNELLQLEFGEVRSQLKLRACNSVFTALENSEDAIEITSEDRVIQYANPAFETTMGYQS
GELIGKELGEVPINEKKADLLDTINSCIRIGKEWQGIYYAKKKNGDNIQQNVKIIPVIGQ
GGKIRHYVSIIRVCNGNNKAEKIPECVQSDTQTDNQTGKHKDRRKGSLDVKAVASRTTEV
SSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVLEILRTTELYSPQF
GAKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKNTQTVSSNIITPISLDDVPPRIARAM
ENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSS
NPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGRTNSFLCNAG
SELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQGIIDMVLATEMTK
HFEHVNKFVNSINKPLATLEENGETDKNQEMINTMLRTPENRTLIKRMLIKCADVSNPCR
PLQYCIEWAARISEEYFSQTDEEKQQDLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDA
WDAFLDLPDLMQHLDNNFKYWKGLDEMKLRSLRPPPE
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgagatttcatcaagatcaacttcaggtacttttagtgtttaccaaagaagataaccaa
tgtaatggattctgcagggcatgtgaaaaagcagggtttaagtgtacagttaccaaggag
gctcaggctgtccttgcctgtttcctggacaaacatcatgacattatcatcatagaccac
agaaatcctcgacaactggatgcagaggcactgtgcaggtctatcagatcatcaaaactc
tcagaaaacacagttattgttggtgtagtacgcagggtggatagagaagagttgtccgta
atgcctttcattgctgctggatttacaaggaggtatgtggaaaaccccaacatcatggcc
tgctacaatgaactgctccagctggagtttggagaggtgcgatcacaactgaaactcagg
gcttgtaactctgtattcactgcattagaaaacagtgaagatgcaattgaaattacaagt
gaagaccgtgttatacagtatgcaaatcctgcatttgaaacaacaatgggctatcagtca
ggtgaattaatagggaaggagttaggagaagtgcctataaatgaaaaaaaggctgacttg
ctcgatactataaattcatgcatcaggataggcaaggagtggcaaggaatttactatgcc
aaaaagaaaaacggagataatatacaacaaaatgtgaagataatacctgtcattggacag
ggaggaaaaattagacactatgtgtccattatcagagtgtgcaatggcaacaataaggct
gagaaaatacccgaatgtgttcagtctgacactcaaacagataatcagacaggcaaacat
aaagacagaagaaaaggctcactagacgtcaaagctgttgcctcccgtacaactgaagtt
tccagccagagacgacactcttctatggcccggatacattccatgacgattgaggcaccc
atcaccaaggtaatcaatattatcaatgctgcccaggaaagtagtcccatgcctgtgacc
gaagccctagaccgtgtgctggaaattctaagaaccactgagttatattcaccacagttt
ggtgctaaggatgatgatccccatgccaatgaccttgttgggggcttaatgtctgatggt
ttgcgaagactatcagggaatgaatatgttctttcaacaaaaaacactcaaacggtttca
agcaatataatcactcccatctcccttgatgatgtcccaccacggatagctcgggccatg
gaaaatgaggaatactgggactttgatatttttgaactggaggctgccacccacaatagg
cctttgatttatcttggtctcaaaatgtttgctcgctttggaatctgtgaattcttacac
tgctctgagtcaacactaagatcatggttacaaattatcgaagccaattatcattcttcc
aatccctaccacaattctacacattctgctgatgtgcttcatgccactgcctattttctc
tccaaggagaggataaaggaaactttagatccaattgatgaggtcgctgcactcattgca
gccaccattcatgatgtggatcaccctgggagaaccaactccttcctgtgtaatgctgga
agtgagctggccattttgtacaatgacactgctgtgctggagagccaccatgcggccttg
gccttccagctgaccactggagatgataaatgcaatatatttaaaaacatggagaggaat
gactatcggacactgcgccagggaattatcgacatggtcttagccacggaaatgacaaag
cactttgagcatgtcaacaaatttgtcaacagcatcaacaaacccttggcaacgctagaa
gaaaatggggaaactgataaaaatcaggaaatgataaacactatgcttaggactccagag
aaccggactctaatcaaacgaatgctgattaaatgtgctgatgtgtccaatccctgccga
cccctgcagtactgcatcgagtgggctgcacgcatttcagaagaatatttttcgcagact
gatgaagagaagcagcaggacttacctgtggtaatgccagtttttgacagaaatacctgc
agcatccccaaatcccaaatctctttcattgattacttcatcacagacatgtttgatgcc
tgggatgcctttctagacctgcctgatttaatgcagcatcttgacaacaactttaaatac
tggaaaggattggacgaaatgaagctgcggagcctccgaccacctcctgaatag
DBGET
integrated database retrieval system
