| Entry |
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| Symbol |
ABCC4
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| Name |
(RefSeq) multidrug resistance-associated protein 4
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| KO |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
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| Organism |
mleu Mandrillus leucophaeus (drill)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:mleu00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
105551428 (ABCC4)
09132 Signal transduction
04024 cAMP signaling pathway
105551428 (ABCC4)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
105551428 (ABCC4)
04981 Folate transport and metabolism
105551428 (ABCC4)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105551428 (ABCC4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:mleu02000]
105551428 (ABCC4)
Transporters [BR:mleu02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
105551428 (ABCC4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1369 aa
MAPAFGPEKGKAPRGRSGGARDSCLPVSPNPCPRGRFCVAGAGTADASLLHLLGRRQDSD
SEFREVSLGWLNPLFKIGHKRRLEEDDMYSVLPEDRSQHLGEELQGFWDKEVLRAENDAQ
KPSLTRAIIKCYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYA
YATVLTVCTLILAILHHLYFYHVQCAGMRLRIAMCHMIYRKALRLSNMAMGKTTTGQIVN
LLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPFQSCFGK
LFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSDLVTNLRKKEISKILRSSYL
RGMNLASFFSASKIIVFVTFTTYVLLGNVITASRVFVAVTLYGAVRLTVTLFFPAAIEKV
SEAIISIRRIQNFLLLDEILQRNRQPPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVR
PGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRVAYVSQQPWVFSGTVRSNILFG
KKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIY
LLDDPLSAVDAEVSRHLFELCICQTLHEKITILVTHQLQYLKAASQILILKDGKMVQKGT
YTEFLKSGIDFGSLLKKDNEESEQLPVPETPTLRNRTFSESSVWSQQSSRPSLKDGAVET
QDTENVPVTLSDENRSEGKVGFQAYKNYFRAGAHWIVIIFLILLNTAAQVAYVLQDWWLS
YWANQQITLNVTVNGGGNVTKKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQT
LHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTVLDFIQTLLQVVSVVSV
AVAVIPWIAIPLVPLGIVFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRA
YKAEGRCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIVVAFGSLILAKTLDA
GQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPPPTWP
HEGVIIFDNVNFMYSLDGPLVLKHLTALIKSREKVGIVGRTGAGKSSLISALFRLSEPEG
KIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLK
ETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQ
KKIREKFAHCTVLTIAHRLNTIIDSDRIMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQL
GKAEAAALTETAKQVYFKRNYPHIGHTDHMVTNTSNGQPSTLTIFETAL |
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| NT seq |
4110 nt +upstreamnt +downstreamnt
atggcacccgcgtttggtcctgagaagggcaaggcgcccagggggcggtctggtggagca
cgagacagctgtctcccagtctccccaaatccgtgcccgagggggcgtttctgcgtcgca
ggggcgggcacagccgacgcctccctgctccaccttctgggtcggcgccaagactcggat
agtgaatttcgggaagtttcactcgggtggctcaatcccttgtttaagattggccataaa
cggagattagaggaagatgatatgtattcagtgctaccagaagaccgctcacagcacctt
ggagaggagttgcaagggttctgggataaagaagttttaagagctgagaatgacgcacag
aagccttctttaacaagagcaatcataaagtgttactggaaatcttatttagttttggga
atttttacattaattgaggaaagtgccaaagtaatccagcccatatttttgggaaaaatt
attaattattttgaaaattacgatcccatggattccgtggctttgaacacagcatacgcc
tatgccacggtgctgactgtttgcacgctcattttggccatactgcatcacttatatttt
tatcacgttcagtgtgctgggatgaggttacgaatagccatgtgccatatgatttatcgg
aaggcacttcgtcttagtaacatggccatggggaagacaaccacaggccagatagtcaat
ctgctgtccaatgatgtcaacaagtttgaccaggtgacagtgttcttacacttcctgtgg
gcagggccactgcaggcgatcgcagtgactgccctactctggatggagataggaatatcg
tgccttgctgggatggcagttctaattattctcctgcccttccaaagctgtttcgggaag
ttgttctcatcactgaggagtaaaactgcaactttcacggatgccaggatcaggaccatg
aatgaagttataactggcataaggataataaaaatgtacgcctgggaaaagtcattttca
gatcttgttaccaatttgagaaagaaggagatttccaagattctgagaagttcctacctc
agagggatgaatttggcctcatttttcagtgcaagcaaaatcatcgtgtttgtgaccttc
accacctatgtgctccttggcaacgtgatcacagccagccgcgtgttcgtggccgtgaca
ctgtacggggctgtgcggctgacggtcaccctcttcttccctgcagccattgagaaggtg
tcagaggcaatcatcagcatccgaagaatccagaactttttgctacttgatgagatattg
cagcgtaaccgtcagccaccgtcagatggtaaaaagatggtgcatgtgcaggactttact
gctttttgggataaggcatcagagaccccaactctacaaggcctttcctttactgtcaga
cctggtgaattgttagctgtggtcggccccgtgggagcagggaagtcatcactgttaagt
gctgtgctcggggaattggcccccagtcacgggctggtcagcgtgcatggaagagttgct
tatgtgtctcagcagccctgggtgttctcgggaactgtgaggagtaatattttatttggg
aagaaatatgaaaaggaacgatatgaaaaagtcataaaggcttgtgctctgaaaaaggat
ttacagctgttggaggatggtgatctgactgtgataggagatcggggaaccacgctgagt
ggagggcagaaagcgcgggtaaaccttgcaagagcagtgtatcaagatgctgacatctat
ctcctggacgatcctctcagcgcagtcgatgcggaagttagcaggcacttgttcgaactg
tgtatttgtcaaactttgcatgagaagatcacaattttagtgactcatcagttgcagtac
ctcaaagctgcaagtcagattctgatattgaaagatggtaaaatggtgcagaaggggact
tacactgagttcctaaaatctggtatagattttggctcccttttgaagaaggacaacgag
gaaagcgaacaacttccagttccagaaactcccacgctgaggaatcgcaccttctcagag
tcttcggtttggtctcagcaatcttctagaccctccttgaaagatggtgctgtggagacc
caagatacggagaatgtcccagttacactctcagacgagaaccgttctgaaggaaaagtt
ggttttcaggcctataagaattacttcagagctggtgctcactggattgtcatcattttc
cttattctcctaaacactgcagctcaggttgcctatgttcttcaagattggtggctttcg
tactgggcaaaccaacaaattacgctaaatgtcactgtaaatggaggaggaaatgtaacc
aagaagctagatcttaactggtacttaggaatttattcaggtttaactgtagctaccgtt
ctttttggcatagcaagatctctattggtattctacgtccttgttaattcttcacaaact
ttgcacaacaaaatgtttgagtcaattctgaaagctccggtattattctttgatagaaat
ccaataggaagaattttaaatcgtttctccaaagacattggacacttggatgatttactg
ccactgacggttttagatttcatccagacattgctacaagtggttagtgtggtctctgtg
gctgtggctgtgattccttggatcgcaatacccttggttccccttggaatcgttttcatt
tttcttcggcgatattttttggaaacatcaagagatgtgaagcgcctggaatctacaact
cggagcccagtgttttcccacttatcatcttctctccagggcctctggaccatccgggca
tacaaagcagaagggaggtgtcaggaactgtttgatgcacaccaggatttacactcagag
gcttggttcttgtttttgacaacatcccgctggttcgccgtccgtctggatgccatctgt
gccatgtttgtcatcgtcgttgcctttgggtccctgattctggcaaaaactctggatgcc
gggcaggtgggcttggcgctgtcctatgccctcacactcatggggatgtttcagtggtgt
gttcgacaaagtgccgaagttgagaatatgatgatctcagtagaaagagtgattgaatac
acagaccttgaaaaagaagcaccttgggaatatcagaaacgcccgccaccgacctggccc
catgaaggagtgatcatctttgacaatgtgaacttcatgtacagtctagatgggcctctg
gtactgaagcatctgacagcactcattaaatcacgagaaaaggttggcattgtgggaaga
accggagctggaaaaagttccctcatctcggccctttttagactgtcagaacccgaaggt
aaaatttggattgataagatcttgacaactgaaattggacttcacgatttaaggaagaaa
atgtcaatcatacctcaggaacctgttttgttcactggaacaatgaggaaaaacctggat
cccttcaatgagcacacggatgaggaactgtggaatgccttacaagaggtacaacttaaa
gaaaccattgaagatcttcctggtaaaatggatactgaattagcagaatcaggatccaat
tttagtgtcggacaaagacaactggtatgccttgccagggcaattctcaggaaaaatcag
atattgattattgatgaagcgacggcaaatgtggatccaagaactgatgagttaatacaa
aagaaaatccgggagaaatttgcccactgcaccgtgctaaccattgcacacagattgaac
accattattgacagcgacaggataatggttttagattcaggaagactgaaagaatatgat
gagccatatgttttgctacaaaataaagagagcctattttacaagatggtgcaacaactg
ggcaaggcagaagccgcggccctcactgaaacagcaaaacaggtatacttcaaaagaaat
tatccacatatcggtcacactgaccatatggttacaaacacttccaatggacagccctca
accttaactattttcgagacagcactatga |
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