Mandrillus leucophaeus (drill): 105551998
Help
Entry
105551998 CDS
T08763
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu00310
Lysine degradation
mleu01100
Metabolic pathways
mleu05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
105551998 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
105551998 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mleu03036
]
105551998 (DOT1L)
Enzymes [BR:
mleu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
105551998 (DOT1L)
Chromosome and associated proteins [BR:
mleu03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
105551998 (DOT1L)
HMT complexes
Dot1-containing complex
105551998 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
105551998
NCBI-ProteinID:
XP_011852865
Ensembl:
ENSMLEG00000039660
LinkDB
All DBs
Position
Unknown
AA seq
1487 aa
AA seq
DB search
MLAGCVGHPALQRDGRPGLMLLLLLVWGLGVALLERPWDKHHDAAHEIIETIRWVCEEIP
DLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRH
ILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQV
VLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWR
ERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGT
IMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRES
KSNAATPTKGPEGKLAGPTDAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGR
KRGRPKKMSTANPERKPKKNQTALDVLHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQR
HSPNPLLVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNTQLLGAA
QQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDN
RALRSQSLQLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEK
SQRQQELLQLKSCVPPDDALSLHLRGKGALGRELEPDASRLHLELDCAKFSLPHLSSMSP
ELSMNGQAAGYELCSALSRPSSKQNTPQYLASPLDQEVVPCTPSHGGRPRLEKLSGLAAP
DYTRLSPAKIVLRRHLSQDHTVPGRPAASELHPRAEHTKENGLPYQSPSVPGSMKLSPQD
PRPLSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVV
LPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGAL
AGSPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSS
PRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTIAAGAGSARQSPSSKHSPLTA
SARGDCVPSHGQDSRKRGRRKRASTGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNS
MVSNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEP
GSEDEPSSARIERKIATISLESKSPPKTLENGGGLAGRKPTPASEPVNNSKWKSTFSPIS
DIGLAKSADSPLQASSTLSQNSLFTFRPALEEPPADAKLATHPRKGFPGSLSGADGLSPS
TNPANGCTFGGGLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKEASDANPFLS
KRQLDGLAGLKGEGSRSKEAGEGAFLPPTSAASLPPANASLSIKLTSLPHKGARPSFTVH
HQPLPRLALAQAAPGIPQASATGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
4464 nt
NT seq
+upstream
nt +downstream
nt
atgctggctggctgtgtgggccatcccgcgcttcagagggatggacggccaggcctcatg
ctgttgctgctcctcgtctggggcttaggggtggccttgctggagaggccatgggacaaa
catcacgatgctgctcatgaaatcatcgagaccatccgatgggtctgtgaagaaatcccg
gatctcaagctcgctatggagaattacgttttaattgactatgacaccaaaagcttcgag
agcatgcagaggctctgcgacaagtacaaccgcgccatcgatagcatccaccagctgtgg
aagggcaccacgcagcccatgaagctgaacacgcggccgtccactgggctcctgcgccac
atcctgcagcaggtctacaaccactcagtgactgaccccgagaagctcaacaactacgag
cccttctcccctgaggtgtacggggagacctccttcgacctggtggcccagatgatcgac
gagatcaagatgaccgacgacgacctgtttgtggacttggggagcggtgtgggccaggtt
gtgctccaggtcgctgctgccaccaactgcaaacatcactatggcgtcgagaaagcggac
atcccggccaagtatgcggagaccatggaccgcgagttcaggaagtggatgaaatggtat
ggaaaaaagcatgcagaatacacattggagagaggcgatttcctctcagaagagtggagg
gagcgaatcgccaacacgagtgttatatttgtgaataattttgcctttggtcctgaggtg
gatcaccagctgaaggagcggtttgcaaacatgaaggaaggtggcagaatcgtgtcctcg
aaaccctttgcacctctgaacttcagaataaacagtagaaacttgagtgacatcggcacc
atcatgcgcgtggtggagctgtcgcctctgaagggctcggtgtcatggacggggaagcca
gtctcctactacctgcacactatcgaccgcaccatacttgaaaactatttttctagtctg
aaaaacccaaaactcagggaggaacaggaggcagcccggcgccgccagcagcgcgagagc
aagagcaacgcggccacgcccaccaagggccccgagggcaagctggctggccccaccgat
gcccccatggactctggtgctgaggaagagaaggcaggagcagccaccgtgaagaagcca
tctccctccaaagcccgcaagaagaagctcaacaagaaggggaggaagatggctggccgc
aagcgcgggcgccccaagaagatgagcactgcgaaccccgagcggaagcccaagaagaac
caaactgcactggatgtcctgcacgctcagaccgtgtctcagacggcagcctcctcgccc
caggatgcctacaggtcccctcacagcccgttctaccagctacctccgagcgtgcagcgt
cactcccccaacccgctgctggtggcgcccaccccgcccgcgttgcagaagctgctagag
tctttcaagatccagtacctgcagttcctggcatacacaaagaccccccagtacaaggcc
agcctacaggagctgctgggccaggagaaggagaagaacacccagctcctgggcgcggct
cagcagctcctcagccactgccaggcccagaaggaggagatcaggaggctgttccagcaa
aaattggatgagctgggcgtgaaggcgctgacctacaacgacctgattcaggcgcagaag
gagatctccgcccacaaccagcagctgcgggagcagtcggagcagctggagcaggacaac
cgtgcgctgcgcagccagagcttgcagctgctcaaggctcgctgcgaggagctgcagctg
gactgggccacgctgtccctggagaagctgctgaaggagaagcaggccctgaagagccag
atctcagagaagcagaggcactgcctggagctgcagatcagcatcgtggagctggagaag
agccagcggcagcaggagctcctgcagctcaagtcctgtgtgccgcctgatgacgccctg
tctctgcacctacgcgggaagggtgccctgggccgcgagctggagcctgacgccagccgg
ctgcacctggagctggactgcgccaagttctcgctgcctcacttgagcagcatgagcccg
gagctctccatgaacggccaggctgccggctatgagctctgcagcgcgctgagccggccc
tcatccaagcagaacacgccccagtacctggcctcacccctcgaccaggaggtggtgccc
tgcacacccagccatggcggccggccgcgcctggagaagctgtctggcctggctgcaccc
gactacaccaggctgtccccggccaagattgtgctgaggcggcacctgagccaggaccac
acggtgcccggcaggccggccgccagtgagctgcacccgagagctgagcacaccaaggag
aacggccttccctaccagagccccagcgtgcctggcagcatgaagctgagtccccaggac
ccgcggcccctgtcacctggggccttgcagcttgctggagagaagagcagtgagaagggc
ctgagagagcgcgcctacggcagcagcggggagctcatcaccagcctgcccatcagcatc
ccgctcagcaccgtgcagcccaacaagctcccggtcagcatccccctggccagcgtggtg
ctgcccagccgcgctgagagggcgaggagcacccccagtcccgtgctgcagccccgcgac
ccctcgtccacacttgaaaagcagattggtgctaatgcccacggcgctgggagcagaagc
cttgccctggcccccgcaggcttctcctatgctggctcggtggccatcagcggggccttg
gcgggcagcccggcctccctcacacctggagccgagccggccaccttggatgagtcctcc
agctctgggagcctttttgccaccgtggggtcccgcagctccacaccacagcaccccctg
ctgctggcacagccccggaactcgctcccggcctctcccgcccaccagctctcctccagt
ccccggcttggtggggctgcccagggcccgctccccgaggccagcaagggggacttgccc
tcagactccggtttctcagatcctgagagtgaggccaagaggaggatcgtgttcaccatc
gccgcgggcgcgggcagtgccagacagtcgccctccagcaagcacagccccctgaccgcc
agcgcccgtggggactgcgtgccgagccacgggcaggacagccgcaagcgtgggcggcgg
aagcgagcatcgacggggacgcccagcttgagcgcaggcgtgtcccccaagcgccgagcc
ctgccgtccgtcgctggccttttcacacaaccttcggggtctcccctcaacctcaactcc
atggtcagtaacatcaaccagcccctggagattacagccatctcgtcccccgagacctcc
ctgaagagctcccctgtgccctaccaggaccacgaccagccccccgtgctcaagaaggag
cggcctctgagccagaccaatggggcacactactccccgctcacctcggacgaggagcca
ggctctgaggatgagcccagcagcgcccgaattgagagaaaaattgcaacaatctcctta
gaaagcaaatctcccccgaaaaccttggaaaatggtggtggcttggcgggaaggaagccc
acgcccgcgagcgagccggtcaacaacagcaagtggaagtctactttctcgcccatctcc
gacatcggcctggccaagtctgcagacagcccgctgcaggccagctccaccctcagccag
aactccctgttcacgttccggcccgccctggaggagccccctgccgatgccaagctggcc
acccaccccaggaaaggctttcctggctctctgtcgggggctgacggactcagcccgagc
accaaccctgccaacggctgcacctttggcgggggcctggccgcggacctgagtttacac
agcttcagcgatggtgcttctcttccccacaagggccccgaggcggccggcctgagctcc
ccgctgagcttcccctcgcagcgtggcaaggaggcctcggacgccaaccctttcctgagc
aagaggcagctggatggcctggctgggctgaagggcgagggcagccgcagcaaggaggca
ggggagggcgctttcttgccccccacctctgctgcctctctgccgcctgctaacgcctct
ttgtctatcaagctcacctccctcccgcacaagggcgcccgcccctccttcacggtgcac
caccagcccctgccccggctggccctggcccaggccgcgcccgggatcccgcaggccagc
gccacggggccgtccgcggtgtgggtgtccctcggcatgccgcctccctatgccgcgcac
ctttcgggggttaagccgcgataa
DBGET
integrated database retrieval system
