Mandrillus leucophaeus (drill): 105552048 Help Entry 105552048         CDS       T08763                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu00220   Arginine biosynthesis mleu00330   Arginine and proline metabolism mleu01100   Metabolic pathways mleu04020   Calcium signaling pathway mleu04066   HIF-1 signaling pathway mleu04146   Peroxisome mleu04371   Apelin signaling pathway mleu04926   Relaxin signaling pathway mleu05010   Alzheimer disease mleu05014   Amyotrophic lateral sclerosis mleu05022   Pathways of neurodegeneration - multiple diseases mleu05133   Pertussis mleu05140   Leishmaniasis mleu05142   Chagas disease mleu05145   Toxoplasmosis mleu05146   Amoebiasis mleu05152   Tuberculosis mleu05200   Pathways in cancer mleu05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:mleu00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     105552048 (NOS2)    00330 Arginine and proline metabolism     105552048 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     105552048 (NOS2)    04066 HIF-1 signaling pathway     105552048 (NOS2)    04020 Calcium signaling pathway     105552048 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     105552048 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     105552048 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105552048 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     105552048 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     105552048 (NOS2)    05152 Tuberculosis     105552048 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     105552048 (NOS2)    05145 Toxoplasmosis     105552048 (NOS2)    05140 Leishmaniasis     105552048 (NOS2)    05142 Chagas disease     105552048 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     105552048 (NOS2)    05014 Amyotrophic lateral sclerosis     105552048 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     105552048 (NOS2) Enzymes [BR:mleu01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      105552048 (NOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  105552048 NCBI-ProteinID:  XP_011852935 Ensembl:  ENSMLEG00000038144 UniProt:  A0A2K5ZJB0 LinkDB All DBs Position Unknown AA seq 1147 aa AA seqDB search MACPWKFLFKTKFHQYTMTGGKDINNNMEKAACATSSLVTQDDLQYHSLSKQQNESPQPL VGTGKKSPESLVKPDATPLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIM TPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARNCSTAREMFEHICRHVRYSTNNGNI RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYG RFDVVPLVLQADGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVG GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINI AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEM LNYVLSPFYYYQVEAWKTHVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVT ILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYSLSCLEEERLLLVVTSTFGNGDCPG NGEKLKKSLFMMKELTNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPVGEGD ELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSSVTWDPHHYRLVQDSQPLDL SKALSNVHAKNVFTMRLKSRQNLQSLTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQ PALVQGILERVVDGPAPHQTVRLEALDESGSYWVSDKRLPPCSLRQALTYFLDITTPPTQ LLLQKLAQVATEATERQRLEALCQPSEYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQL PILKPRFYSISSSRDHTPTEIHLTVAVVTYHTQDGQGPLHHGVCSTWLNSLKPQDPVPCF IRNASGFHLPEDPSHPCILVGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPD EDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLQGHLYVCG DVRMAWDVAHTLKQLVAAKLNLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDGAAV QPRSLAM NT seq 3444 nt NT seq  +upstreamnt  +downstreamnt atggcctgtccttggaaatttctgttcaagaccaaattccaccagtatacaatgactggg ggaaaagacatcaacaacaacatggagaaagccgcctgtgccacctccagtctagtgaca caggatgaccttcagtatcacagcctcagcaagcagcagaatgagtccccgcagcccctc gtggggacaggaaagaagtctccagaatctctggtcaagccggatgcaaccccattgtcc tccccacggcacgtgaggatcaaaaactggggcagcgggatgactttccaggacacactt caccacaaggccaaagggattttgacttgcaggtccaaatcttgcttggggtccattatg actcccaaaagtttgaccagaggacccagggacaagcctacccctccagatgagcttcta cctcaagctatcgaatttgtcaaccaatattacggctccttcaaagaggcaaaaatagag gaacatctggccagggtggaagcggtaacaaaggagatagaaacaacaggaacctaccaa ctgacgggagatgagctcatcttcgccaccaagcaggcctggcgcaatgccccacgctgc attgggaggatccagtggtccaacctgcaggtcttcgatgcccgcaactgttccaccgcc cgggaaatgtttgaacacatctgcagacacgtgcgttactccaccaacaatggcaacatc aggtcggccatcaccgtgttcccccagcggagcgatggtaagcacgacttccgggtgtgg aatgctcagctcatccgctacgcgggctaccagatgccagatggcagcatcagaggggat cctgccaacgtggaattcactcagctgtgcatcgacctgggctggaagcccaagtatggc cgcttcgatgtggtccccctggtcctacaggctgacggccgtgaccctgagctcttcgaa atcccacctgaccttgtgcttgaggtggccatggaacatcccaaatatgagtggtttcgg gaactggagctaaagtggtacgccctgcctgcagtggccaacatgctgctcgaggtgggc ggcctggagttcccagggtgccccttcaatggctggtacatgggcacagagatcggagtc cgggacttctgtgacgtccaacgctacaacatcctggaggaagtgggcaggagaatgggc ttggaaacgcacaagctggcctcgctctggaaagaccaggctgtcgttgagatcaacatt gctgtgctccatagtttccagaagcaaaacgtgaccatcatggaccaccactcagctgca gaatccttcatgaagtacatgcaaaatgaataccggtcccgtgggggctgcccggcagac tggatttggctagtccctcccatgtctggaagcatcactcccgtgtttcaccaggagatg ctgaactacgtcctgtcccctttctactactatcaggtagaggcttggaaaacccatgtc tggcaggacgagaagcggagacccaagaggagagagattccgttgaaagtcttggtcaaa gctgtgctctttgcctgtatgctgatgcgcaagacgatggcgtcccgagtcagagtcact atcctctttgcgacagagacaggaaaatcagaggcgctggcctgggacctgggggccttg ttcagctgtgccttcaaccccaaggttgtctgcatggataagtacagtctgagctgcctg gaggaggagcggctgctgttggtggtgaccagtacgtttggcaatggagactgccccggc aatggagagaaactgaagaaatcgctcttcatgatgaaagagctcaccaacaaattcagg tatgccgtgtttggccttggctccagcatgtaccctcggttctgcgcctttgctcatgac atcgatcagaagctgtcccacctgggggcctctcagctcacccctgtgggagaaggggat gagctcagcgggcaggaggacgccttccgcagctgggccgtgcaaaccttcaaggcagcc tgtgagacgtttgatgtccgaggcaaacagcacattcagatccccaagctctacacctcc agtgtgacctgggacccacaccactacaggctcgtgcaggactcacagcctttggacctc agcaaagccctcagcaacgtgcacgccaagaacgtgttcaccatgaggctcaaatctcgg cagaatctacagagtctgacatccagccgtgccaccatcctggtggaactctcctgtgaa gacggccaaggcctgaactacttgccgggggagcacctcggggtttgcccaggcaaccag ccggccctggtccaaggcatcctggagcgagtggtggacggccccgcaccccaccagaca gtgcgcctggaggccctggacgagagtggcagctactgggtcagtgacaagaggctgccc ccctgctcgctcaggcaggccctcacctacttcctggatatcaccacccccccaacccag ctgctgctccaaaagctggcccaggtggccacagaagcgactgagagacagaggctggag gccctgtgccagccctcagagtacagcaagtggaagttcaccaacagccccacgttcctg gaggtgctggaggagttcccatccctgcgggtgtctgctggcttcctgctttcccagctc cccattctgaagcccaggttctactccatcagctcctcccgggatcacacgcccacggag atccacctgactgtggccgtggtcacgtaccacacccaagatggccagggtcccctgcac cacggcgtctgcagcacatggctcaacagcctgaagccccaagacccagtgccctgcttt atacgaaacgccagcggcttccacctccccgaggacccctcccatccttgcatcctggtc gggcctggcacaggcatcgcccccttccgcagtttctggcagcagcggctccatgactcc cagcacaagggagtgcggggaggccgcatgaccttggtgtttgggtgccgccgcccagat gaggaccacatctaccaggaggagatgctggagatggcccagaagggggtgctgcatgcg gtgcacacagcctattctcgcctgcctggcaagcccaaggtctatgttcaggacatcctg cggcagcagctggccagcgaggtgctccgtgtgctccagggccacctctatgtttgcggg gatgtgcgcatggcctgggatgtggcccacaccctgaagcagctggtggctgccaagctg aacttgaatgaggagcaggtcgaggactatttctttcagctcaagagccagaagcgctat catgaagatatctttggtgctgtatttccctacgaggcgaagaaggacggggcggcagtg cagcccaggagcctggcgatgtaa

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