Mandrillus leucophaeus (drill): 105553148
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Entry
105553148 CDS
T08763
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu00230
Purine metabolism
mleu00670
One carbon pool by folate
mleu01100
Metabolic pathways
mleu01523
Antifolate resistance
Module
mleu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
105553148 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
105553148 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105553148 (GART)
Enzymes [BR:
mleu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
105553148 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
105553148 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
105553148 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
Dala_Dala_lig_C
ATP-grasp_4
ATP-grasp_3
Sacchrp_dh_NADP
ATP-grasp_5
RimK
GAE_BBS1
Motif
Other DBs
NCBI-GeneID:
105553148
NCBI-ProteinID:
XP_011854508
Ensembl:
ENSMLEG00000033385
UniProt:
A0A2K5YSE5
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNNAISISDHTALAQ
FCKEEKIEFVVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWKAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFSEA
QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLVSALEEAKKGLAAIKFEGAIYRKD
IGFRAIAFLQQPRGLTYKESGVDIAAGNTLVKKIQPLAEATSRSGCKVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSFLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPKVFSWLQQEG
QLSEEEMARTFNCGVGAALVVSKEQTAQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
LIESMQINGSVLKNGSLKNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDNAIDLVLEEFSIDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVATLSERVKVAEHKTFPAALQLVASGTVQLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttataattggcagtggaggaagggaacatacgctggcctggaaa
cttgcacagtctcatcatgtcaaacaagtgttggttgccccaggaaatgcaggcactgcc
tgctctgaaaagatttcaaataacgccatctcaatcagtgaccacactgcccttgctcaa
ttctgcaaagaggagaaaattgaattcgtagttgttggaccagaagcacctctggctgct
gggattgttgggaacctgacgtctgcaggagtgcgatgctttggcccaacagcagaagcg
gctcagttagagtccagcaaaaggtttgccaaagagtttatggacagacatggaatccca
actgcgcaatggaaggctttcaccaaacctgaagaggcctgcagcttcattatgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcggctggaaaaggggtgattgtt
gcaaagagcaaagaagaggcctgcaaagctgtacaagagatcatgcaggagaaagccttt
ggagcagccggagaaacaattgtcattgaagaacttcttgacggagaagaagtgtcttgt
ctgtgcttcactgatggcaagactgtggcccccatgccaccggcgcaggaccataagcga
ttactggagggagatggcggccctaacacagggggaatgggagcctattgtccggcccct
caggtttctaatgatctattactaaaaattaaagatactgttcttcagaggacagtggat
ggcatgcagcaagagggtactccatatacaggtattctctatgctggaataatgctgacc
aaggatggcccaaaagttctagagtttaattgccgttttggtgatccagagtgccaagta
atcctcccacttcttaaaagtgatctttatgaagtgattcagtccaccttagatggactg
ctctgcacatctctgcctgtttggctagaaaaccacaccgccctaactgttgtcatggcc
agtaaaggttatcctggagactacaccaagggtgtagagataacagggttttccgaggct
caagctctaggactggaggtgttccacgcaggcactgcccttaaaaatggcaaagtagta
actcatgggggtagagttcttgcagtcacagccatccgggaaaatctcgtatcagctctc
gaggaagccaagaaaggactagcagctataaagtttgagggagcaatttataggaaagac
attggctttcgtgccatagctttcctccagcagcccaggggtttgacttacaaggaatct
ggagtagacattgcagctggaaatacgctggtcaagaaaattcagcctttagcggaagcc
acttccagatcaggctgtaaagttgatcttggaggttttgctggtctttttgatttaaaa
gcagctggtttcaaagatccccttctggcctctggaacagatggcgttggaactaaacta
aagattgcccagctgtgcaacaaacatgataccattggtcaagatttggtagcaatgtgt
gttaatgatattctggcacaaggagcagagcccctcttcttccttgattacttttcctgt
ggaaaacttgacctcagtgtaactgaagccgttgttgctggaattgctaaagcttgtgga
aaagctggatgtgctcttcttggaggtgaaacagcagaaatgcctgacatgtatccccct
ggagagtatgacctagctgggtttgccgttggtgccatggagcgagatcagaaactccct
cacctggaaagaatcaccgagggtgatgttgttgttggaatagcttcatctggtcttcat
agcaatggatttagccttgtgaggaagatcgtggcaaaatctttcctccagtactcctct
ccagcacctgatggttgtggtgaccagactttaggggacttacttctcacgccaaccaga
atctacagccattcactgttacctgtcctacgttcaggacatgtcaaagcgtttgcccat
attactggtggaggattactagagaacatccccagagtcctccctgagaaacttggggta
gatttagatgcccagacctggaggatccccaaagtcttctcatggttacagcaggaagga
caactctctgaggaagagatggccagaacatttaactgtggggttggcgctgcccttgtg
gtatcaaaggagcagacagcgcagattctgagggatatccagcagcacaaggaagaagcc
tgggtgattggcagtgtggttgcacgagccgaaggttctccacgtgtgaaagtcaagaat
ctgattgaaagcatgcaaataaatgggtcagtgttgaagaatggctccctgaaaaatcat
ttctcttttgaaaaaaaaaaggccagagtggctgtcttaatatctggaacaggatcgaac
ctgcaagcacttatagacagtactcgggaaccaaatagctctgcacaaattgatgttgtt
atctccaacaaagccgcagtagctgggttagataaagcggaaagagctggtattcccact
agagtaattaatcataaactgtataaaaatcgtgtagaatttgacaatgcaattgaccta
gtccttgaagagttctccatagacatagtctgtcttgcgggattcatgagaattctttct
ggcccctttgtccgaaagtggaatggaaaaatgctcaatatccacccatccttgctccct
tcttttaagggttcgaatgcccatgagcaagccctggaaaccggagtcacagttactggg
tgtactgtacactttgtagctgaagatgtagatgctggacaaattattttgcaagaagct
gttcccgtgaagaggggtgatactgttgcaactctttctgaaagagtaaaagtagcagaa
cataaaacatttcctgcagccctccagttggtggccagtggaactgtacagcttggagaa
aatggcaagatctgttgggttaaagaggaatga
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